4rzf - Revision history

OCA at 12:57, 1 March 2024

OCA — Fri, 01 Mar 2024 12:57:18 GMT

←Older revision		Revision as of 12:57, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RZF FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RZF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.99Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [https://pdbe.org/4rzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [https://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [https://pdbe.org/4rzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [https://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>		[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Sepsis, a hyperinflammatory response that can result in multiple organ dysfunctions, is a leading cause of mortality from infection. Here, we show that orphan nuclear receptor Nur77 (also known as TR3) can enhance resistance to lipopolysaccharide (LPS)-induced sepsis in mice by inhibiting NF-kappaB activity and suppressing aberrant cytokine production. Nur77 directly associates with p65 to block its binding to the kappaB element. However, this function of Nur77 is countered by the LPS-activated p38alpha phosphorylation of Nur77. Dampening the interaction between Nur77 and p38alpha would favor Nur77 suppression of the hyperinflammatory response. A compound, n-pentyl 2-[3,5-dihydroxy-2-(1-nonanoyl) phenyl]acetate, screened from a Nur77-biased library, blocked the Nur77-p38alpha interaction by targeting the ligand-binding domain of Nur77 and restored the suppression of the hyperinflammatory response through Nur77 inhibition of NF-kappaB. This study associates the nuclear receptor with immune homeostasis and implicates a new therapeutic strategy to treat hyperinflammatory responses by targeting a p38alpha substrate to modulate p38alpha-regulated functions.
-
-	Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.,Li L, Liu Y, Chen HZ, Li FW, Wu JF, Zhang HK, He JP, Xing YZ, Chen Y, Wang WJ, Tian XY, Li AZ, Zhang Q, Huang PQ, Han J, Lin T, Wu Q Nat Chem Biol. 2015 May;11(5):339-46. doi: 10.1038/nchembio.1788. Epub 2015 Mar, 30. PMID:25822914<ref>PMID:25822914</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4rzf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:35, 15 March 2023

OCA — Wed, 15 Mar 2023 10:35:26 GMT

←Older revision		Revision as of 10:35, 15 March 2023
Line 1:		Line 1:

	==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant==		==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant==
-	<StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>	+	<StructureSection load='4rzf' size='340' side='right'caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4RZF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RZF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rze\|4rze]], [[4rzg\|4rzg]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [https://pdbe.org/4rzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [https://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [~~http~~://pdbe.org/4rzf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>	+	[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: Chen, H]]	+	[[Category: Large Structures]]
-	[[Category: Li, A]]	+	[[Category: Chen H]]
-	[[Category: Li, F]]	+	[[Category: Li A]]
-	[[Category: Li, L]]	+	[[Category: Li F]]
-	[[Category: Lin, T]]	+	[[Category: Li L]]
-	[[Category: Liu, Y]]	+	[[Category: Lin T]]
-	[[Category: Tian, X]]	+	[[Category: Liu Y]]
-	[[Category: Wu, Q]]	+	[[Category: Tian X]]
-	~~[[Category: Transcription~~]]	+	[[Category: Wu Q]]

OCA at 09:12, 22 November 2017

OCA — Wed, 22 Nov 2017 09:12:40 GMT

←Older revision		Revision as of 09:12, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>		<StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rze\|4rze]], [[4rzg\|4rzg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rze\|4rze]], [[4rzg\|4rzg]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [http://pdbe.org/4rzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [http://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [http://pdbe.org/4rzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [http://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>
	</table>		</table>
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Chen, H]]		[[Category: Chen, H]]
	[[Category: Li, A]]		[[Category: Li, A]]

OCA at 01:44, 10 March 2017

OCA — Fri, 10 Mar 2017 01:44:57 GMT

←Older revision		Revision as of 01:44, 10 March 2017
Line 1:		Line 1:
		+
	==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant==		==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant==
	<StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>		<StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rze\|4rze]], [[4rzg\|4rzg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rze\|4rze]], [[4rzg\|4rzg]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [http://www.ebi.ac.uk/pdbsum/4rzf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [http://pdbe.org/4rzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [http://www.ebi.ac.uk/pdbsum/4rzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rzf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4rzf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:30, 22 April 2015

OCA — Wed, 22 Apr 2015 06:30:27 GMT

←Older revision		Revision as of 06:30, 22 April 2015
Line 9:		Line 9:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>		[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sepsis, a hyperinflammatory response that can result in multiple organ dysfunctions, is a leading cause of mortality from infection. Here, we show that orphan nuclear receptor Nur77 (also known as TR3) can enhance resistance to lipopolysaccharide (LPS)-induced sepsis in mice by inhibiting NF-kappaB activity and suppressing aberrant cytokine production. Nur77 directly associates with p65 to block its binding to the kappaB element. However, this function of Nur77 is countered by the LPS-activated p38alpha phosphorylation of Nur77. Dampening the interaction between Nur77 and p38alpha would favor Nur77 suppression of the hyperinflammatory response. A compound, n-pentyl 2-[3,5-dihydroxy-2-(1-nonanoyl) phenyl]acetate, screened from a Nur77-biased library, blocked the Nur77-p38alpha interaction by targeting the ligand-binding domain of Nur77 and restored the suppression of the hyperinflammatory response through Nur77 inhibition of NF-kappaB. This study associates the nuclear receptor with immune homeostasis and implicates a new therapeutic strategy to treat hyperinflammatory responses by targeting a p38alpha substrate to modulate p38alpha-regulated functions.
		+
		+	Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.,Li L, Liu Y, Chen HZ, Li FW, Wu JF, Zhang HK, He JP, Xing YZ, Chen Y, Wang WJ, Tian XY, Li AZ, Zhang Q, Huang PQ, Han J, Lin T, Wu Q Nat Chem Biol. 2015 May;11(5):339-46. doi: 10.1038/nchembio.1788. Epub 2015 Mar, 30. PMID:25822914<ref>PMID:25822914</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:14, 18 March 2015

OCA — Wed, 18 Mar 2015 12:14:11 GMT

←Older revision		Revision as of 12:14, 18 March 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant==
-		+	<StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution\|resolution]] 1.99Å' scene=''>
-	~~The entry~~ 4rzf is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZF FirstGlance]. <br>
-	~~Authors~~: ~~Fengwei, L~~.~~, Xuyang, T~~.~~, Anzhong, L~~.~~, Li, L~~.~~, Yuan, L~~.~~, Hangzi, C~~.~~, Qiao, W~~.~~, Tianwei, L~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4rze\|4rze]], [[4rzg\|4rzg]]</td></tr>
-	~~Description: Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [http://www.ebi.ac.uk/pdbsum/4rzf PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Fengwei~~, L]]	+	== Function ==
-	[[~~Category~~: ~~Xuyang~~, T]]	+	[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
-	[[~~Category~~: ~~Yuan, L~~]]	+	== References ==
-	[[Category: ~~Anzhong~~, L]]	+	<references/>
-	[[Category: ~~Tianwei~~, L]]	+	__TOC__
-	[[Category: ~~Hangzi~~, C]]	+	</StructureSection>
		+	[[Category: Chen, H]]
		+	[[Category: Li, A]]
		+	[[Category: Li, F]]
	[[Category: Li, L]]		[[Category: Li, L]]
-	[[Category: ~~Qiao~~, W]]	+	[[Category: Lin, T]]
		+	[[Category: Liu, Y]]
		+	[[Category: Tian, X]]
		+	[[Category: Wu, Q]]
		+	[[Category: Transcription]]

OCA at 14:06, 21 January 2015

OCA — Wed, 21 Jan 2015 14:06:56 GMT

←Older revision		Revision as of 14:06, 21 January 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4rzf is ON HOLD	+	The entry 4rzf is ON HOLD until Paper Publication

	Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L.		Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L.

OCA: Protected "4rzf" [edit=sysop:move=sysop]

OCA — Wed, 31 Dec 2014 12:17:08 GMT

Protected "4rzf" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:17, 31 December 2014

OCA: New page: '''Unreleased structure''' The entry 4rzf is ON HOLD Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L. Description: Crystal Structure A...

OCA — Wed, 31 Dec 2014 12:17:07 GMT

New page: '''Unreleased structure''' The entry 4rzf is ON HOLD Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L. Description: Crystal Structure A...

New page

'''Unreleased structure'''

The entry 4rzf is ON HOLD

Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L.

Description: Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant
[[Category: Unreleased Structures]]
[[Category: Fengwei, L]]
[[Category: Xuyang, T]]
[[Category: Yuan, L]]
[[Category: Anzhong, L]]
[[Category: Tianwei, L]]
[[Category: Hangzi, C]]
[[Category: Li, L]]
[[Category: Qiao, W]]