4s3l - Revision history

OCA at 10:42, 15 March 2023

OCA — Wed, 15 Mar 2023 10:42:58 GMT

←Older revision		Revision as of 10:42, 15 March 2023
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	<StructureSection load='4s3l' size='340' side='right'caption='[[4s3l]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='4s3l' size='340' side='right'caption='[[4s3l]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strzt Strzt~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4S3L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_Taiwan19F-14 Streptococcus pneumoniae Taiwan19F-14]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S3L FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pitB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487213 STRZT])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [https://pdbe.org/4s3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [https://www.ebi.ac.uk/pdbsum/4s3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s3l ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [~~http~~://pdbe.org/4s3l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4s3l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4s3l ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B3FNT1_STREE B3FNT1_STREE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
-	*[[Pilin\|Pilin]]	+	*[[Pilin 3D structures\|Pilin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strzt~~]]	+	[[Category: Streptococcus pneumoniae Taiwan19F-14]]
-	[[Category: Dessen, A]]	+	[[Category: Dessen A]]
-	[[Category: Guilmi~~, A M.Di~~]]	+	[[Category: Di Guilmi AM]]
-	[[Category: Shaik~~, M M]]~~	+	[[Category: Shaik MM]]
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Cnab]]~~	+
-	~~[[Category: Igg fold]]~~	+
-	~~[[Category: Igg-rev fold]]~~	+
-	~~[[Category: Major pilin]]~~	+
-	~~[[Category: Pilin protein]]~~	+
-	~~[[Category: Type ii pilus]]~~	+
-	~~[[Category: Virulence~~]]	+

OCA at 10:23, 1 May 2019

OCA — Wed, 01 May 2019 10:23:57 GMT

←Older revision		Revision as of 10:23, 1 May 2019
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		+
	==Crystal Structure of major pilin protein PitB from type II pilus of Streptococcus pneumoniae==		==Crystal Structure of major pilin protein PitB from type II pilus of Streptococcus pneumoniae==
-	<StructureSection load='4s3l' size='340' side='right' caption='[[4s3l]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='4s3l' size='340' side='right'caption='[[4s3l]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S3L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strzt Strzt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S3L FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://pdbe.org/4s3l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pitB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487213 STRZT])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://pdbe.org/4s3l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4s3l ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 4s3l" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4s3l" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Pilin\|Pilin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Strzt]]
	[[Category: Dessen, A]]		[[Category: Dessen, A]]
	[[Category: Guilmi, A M.Di]]		[[Category: Guilmi, A M.Di]]

OCA at 07:46, 7 October 2015

OCA — Wed, 07 Oct 2015 07:46:06 GMT

←Older revision		Revision as of 07:46, 7 October 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S3L FirstGlance]. <br>		<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S3L FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://pdbe.org/4s3l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4s3l" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:46, 26 August 2015

OCA — Wed, 26 Aug 2015 07:46:18 GMT

←Older revision		Revision as of 07:46, 26 August 2015
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	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pili are fibrous appendages expressed on the surface of a vast number of bacterial species, and their role in surface adhesion is important for processes such as infection, colonization, and biofilm formation. The human pathogen Streptococcus pneumoniae expresses two different types of pili, PI-1 and PI-2, both of which require the concerted action of structural proteins and sortases for their polymerization. The type PI-1 streptococcal pilus is a complex, well-studied structure, but the PI-2 type, present in a number of invasive pneumococcal serotypes, has to date remained less well understood. The PI-2 pilus consists of repeated units of a single protein, PitB, whose covalent association is catalyzed by cognate sortase SrtG-1 and partner protein SipA. Here we report the high-resolution crystal structures of PitB and SrtG1 and use molecular modeling to visualize a 'trapped' 1:1 complex between the two molecules. X-ray crystallography and electron microscopy reveal that the pneumococcal PI-2 backbone fiber is formed by PitB monomers associated in 'head-to-tail' fashion, and that short, flexible fibers can be formed even in the absence of coadjuvant proteins. These observations, obtained with a simple pilus biosynthetic system, are likely to be applicable to other fiber formation processes in a variety of Gram-positive organisms.
		+
		+	A structural snapshot of type II pilus formation in Streptococcus pneumoniae.,Shaik MM, Lombardi C, Maragno Trindade D, Fenel D, Schoehn G, Di Guilmi AM, Dessen A J Biol Chem. 2015 Jul 21. pii: jbc.M115.647834. PMID:26198632<ref>PMID:26198632</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:47, 29 July 2015

OCA — Wed, 29 Jul 2015 14:47:29 GMT

←Older revision		Revision as of 14:47, 29 July 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal Structure of major pilin protein PitB from type II pilus of Streptococcus pneumoniae==
-		+	<StructureSection load='4s3l' size='340' side='right' caption='[[4s3l]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~The entry~~ 4s3l is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4s3l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S3L FirstGlance]. <br>
-	~~Authors~~: ~~Shaik, M~~.M.~~, Dessen, A~~.~~, Di Guilmi, A~~.M.	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4s3l RCSB], [http://www.ebi.ac.uk/pdbsum/4s3l PDBsum]</span></td></tr>
-		+	</table>
-	~~Description~~: ~~Crystal Structure of major pilin protein PitB from type II pilus of Streptococcus pneumoniae~~	+	__TOC__
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</StructureSection>
	[[Category: Dessen, A]]		[[Category: Dessen, A]]
-	[[Category: Di Guilmi, A.M]]	+	[[Category: Guilmi, A M.Di]]
-	[[Category: Shaik, M.M]]	+	[[Category: Shaik, M M]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Cnab]]
		+	[[Category: Igg fold]]
		+	[[Category: Igg-rev fold]]
		+	[[Category: Major pilin]]
		+	[[Category: Pilin protein]]
		+	[[Category: Type ii pilus]]
		+	[[Category: Virulence]]

OCA: Protected "4s3l" [edit=sysop:move=sysop]

OCA — Wed, 18 Feb 2015 09:53:09 GMT

Protected "4s3l" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:53, 18 February 2015

OCA: New page: '''Unreleased structure''' The entry 4s3l is ON HOLD until Paper Publication Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M. Description: Crystal Structure of major pilin protein Pit...

OCA — Wed, 18 Feb 2015 09:53:08 GMT

New page: '''Unreleased structure''' The entry 4s3l is ON HOLD until Paper Publication Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M. Description: Crystal Structure of major pilin protein Pit...

New page

'''Unreleased structure'''

The entry 4s3l is ON HOLD until Paper Publication

Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M.

Description: Crystal Structure of major pilin protein PitB from type II pilus of Streptococcus pneumoniae
[[Category: Unreleased Structures]]
[[Category: Dessen, A]]
[[Category: Di Guilmi, A.M]]
[[Category: Shaik, M.M]]