4u3y - Revision history

OCA at 00:49, 28 December 2023

OCA — Thu, 28 Dec 2023 00:49:52 GMT

←Older revision		Revision as of 00:49, 28 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [https://pdbe.org/4u3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [https://www.ebi.ac.uk/pdbsum/4u3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [https://pdbe.org/4u3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [https://www.ebi.ac.uk/pdbsum/4u3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3y ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:00, 22 March 2023

OCA — Wed, 22 Mar 2023 08:00:53 GMT

←Older revision		Revision as of 08:00, 22 March 2023
Line 3:		Line 3:
	<StructureSection load='4u3y' size='340' side='right'caption='[[4u3y]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='4u3y' size='340' side='right'caption='[[4u3y]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4u3z\|4u3z]], [[4u40\|4u40]], [[4u41\|4u41]], [[4u42\|4u42]], [[4u43\|4u43]], [[4u44\|4u44]], [[4u45\|4u45]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [https://pdbe.org/4u3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [https://www.ebi.ac.uk/pdbsum/4u3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3y ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MAP4K4, HGK, KIAA0687, NIK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [~~http~~://pdbe.org/4u3y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4u3y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3y ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/M4K4_HUMAN M4K4_HUMAN]] Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.<ref>PMID:9890973</ref> <ref>PMID:21690388</ref>	+	[https://www.uniprot.org/uniprot/M4K4_HUMAN M4K4_HUMAN] Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.<ref>PMID:9890973</ref> <ref>PMID:21690388</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Non-specific serine/threonine protein kinase]]~~	+	[[Category: Coons M]]
-	[[Category: Coons, M]]	+	[[Category: Harris SF]]
-	[[Category: Harris~~, S F~~]]	+	[[Category: Wu P]]
-	[[Category: Wu, P]]	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 14:42, 10 May 2019

OCA — Fri, 10 May 2019 14:42:19 GMT

←Older revision		Revision as of 14:42, 10 May 2019
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		+
	==Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)==		==Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)==
-	<StructureSection load='4u3y' size='340' side='right' caption='[[4u3y]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='4u3y' size='340' side='right'caption='[[4u3y]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4u3z\|4u3z]], [[4u40\|4u40]], [[4u41\|4u41]], [[4u42\|4u42]], [[4u43\|4u43]], [[4u44\|4u44]], [[4u45\|4u45]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4u3z\|4u3z]], [[4u40\|4u40]], [[4u41\|4u41]], [[4u42\|4u42]], [[4u43\|4u43]], [[4u44\|4u44]], [[4u45\|4u45]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MAP4K4, HGK, KIAA0687, NIK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [http://pdbe.org/4u3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [http://www.ebi.ac.uk/pdbsum/4u3y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [http://pdbe.org/4u3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [http://www.ebi.ac.uk/pdbsum/4u3y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Coons, M]]		[[Category: Coons, M]]

OCA at 11:30, 7 January 2016

OCA — Thu, 07 Jan 2016 11:30:25 GMT

←Older revision		Revision as of 11:30, 7 January 2016
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)==
-		+	<StructureSection load='4u3y' size='340' side='right' caption='[[4u3y]], [[Resolution\|resolution]] 1.45Å' scene=''>
-	~~The entry~~ 4u3y is ~~ON HOLD until Jan 04 2017~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4u3y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3Y FirstGlance]. <br>
-	~~Authors~~: ~~Harris~~, ~~S.F.~~, Wu, P., ~~Coons~~, M.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4u3z\|4u3z]], [[4u40\|4u40]], [[4u41\|4u41]], [[4u42\|4u42]], [[4u43\|4u43]], [[4u44\|4u44]], [[4u45\|4u45]]</td></tr>
-	~~Description~~: ~~Apo Mitogen~~-~~activated~~ protein kinase ~~kinase kinase kinase 4 (MAP4K4)~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3y OCA], [http://pdbe.org/4u3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u3y RCSB], [http://www.ebi.ac.uk/pdbsum/4u3y PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Harris, S~~.F]]	+	</table>
-	[[Category: ~~Wu, P~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/M4K4_HUMAN M4K4_HUMAN]] Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.<ref>PMID:9890973</ref> <ref>PMID:21690388</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Coons, M]]		[[Category: Coons, M]]
		+	[[Category: Harris, S F]]
		+	[[Category: Wu, P]]
		+	[[Category: Kinase]]
		+	[[Category: Transferase]]

OCA at 10:17, 8 July 2015

OCA — Wed, 08 Jul 2015 10:17:18 GMT

←Older revision		Revision as of 10:17, 8 July 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4u3y is ON HOLD until ~~Paper Publication~~	+	The entry 4u3y is ON HOLD until Jan 04 2017

	Authors: Harris, S.F., Wu, P., Coons, M.		Authors: Harris, S.F., Wu, P., Coons, M.

OCA at 18:07, 24 December 2014

OCA — Wed, 24 Dec 2014 18:07:03 GMT

←Older revision		Revision as of 18:07, 24 December 2014
Line 6:		Line 6:

	Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)		Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)
		+	[[Category: Unreleased Structures]]
		+	[[Category: Harris, S.F]]
		+	[[Category: Wu, P]]
		+	[[Category: Coons, M]]

OCA at 06:53, 26 November 2014

OCA — Wed, 26 Nov 2014 06:53:23 GMT

←Older revision		Revision as of 06:53, 26 November 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4u3y is ON HOLD	+	The entry 4u3y is ON HOLD until Paper Publication

	Authors: Harris, S.F., Wu, P., Coons, M.		Authors: Harris, S.F., Wu, P., Coons, M.

	Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)		Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)

OCA: Protected "4u3y" [edit=sysop:move=sysop]

OCA — Wed, 30 Jul 2014 07:15:51 GMT

Protected "4u3y" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:15, 30 July 2014

OCA: New page: '''Unreleased structure''' The entry 4u3y is ON HOLD Authors: Harris, S.F., Wu, P., Coons, M. Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)

OCA — Wed, 30 Jul 2014 07:15:50 GMT

New page: '''Unreleased structure''' The entry 4u3y is ON HOLD Authors: Harris, S.F., Wu, P., Coons, M. Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)

New page

'''Unreleased structure'''

The entry 4u3y is ON HOLD

Authors: Harris, S.F., Wu, P., Coons, M.

Description: Apo Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)