4u93 - Revision history

OCA at 00:50, 28 December 2023

OCA — Thu, 28 Dec 2023 00:50:29 GMT

←Older revision		Revision as of 00:50, 28 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U93 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U93 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [https://pdbe.org/4u93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [https://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [https://pdbe.org/4u93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [https://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:10, 22 March 2023

OCA — Wed, 22 Mar 2023 08:10:00 GMT

←Older revision		Revision as of 08:10, 22 March 2023
Line 3:		Line 3:
	<StructureSection load='4u93' size='340' side='right'caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4u93' size='340' side='right'caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4U93 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U93 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [~~http~~://pdbe.org/4u93 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [https://pdbe.org/4u93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [https://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>	+	[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bellamacina~~, C R~~]]	+	[[Category: Bellamacina CR]]
-	[[Category: Bussiere, D]]	+	[[Category: Bussiere D]]
-	[[Category: Shafer~~, C M]]~~	+	[[Category: Shafer CM]]
-	~~[[Category: Atp-binding domain]]~~	+
-	~~[[Category: Chaperone~~]]	+

OCA at 10:45, 26 February 2020

OCA — Wed, 26 Feb 2020 10:45:43 GMT

←Older revision		Revision as of 10:45, 26 February 2020
Line 1:		Line 1:

	==Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990==		==Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990==
-	<StructureSection load='4u93' size='340' side='right' caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='4u93' size='340' side='right'caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4u93" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4u93" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Bellamacina, C R]]		[[Category: Bellamacina, C R]]
	[[Category: Bussiere, D]]		[[Category: Bussiere, D]]

OCA at 09:21, 22 November 2017

OCA — Wed, 22 Nov 2017 09:21:51 GMT

←Older revision		Revision as of 09:21, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4u93' size='340' side='right' caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4u93' size='340' side='right' caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://pdbe.org/4u93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://pdbe.org/4u93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4u93" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4u93" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Heat Shock Proteins\|Heat Shock Proteins]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Bellamacina, C R]]		[[Category: Bellamacina, C R]]
	[[Category: Bussiere, D]]		[[Category: Bussiere, D]]

OCA at 06:25, 26 July 2016

OCA — Tue, 26 Jul 2016 06:25:20 GMT

←Older revision		Revision as of 06:25, 26 July 2016
Line 1:		Line 1:
		+
	==Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990==		==Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990==
	<StructureSection load='4u93' size='340' side='right' caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4u93' size='340' side='right' caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://pdbe.org/4u93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u93 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4u93" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Heat Shock Proteins\|Heat Shock Proteins]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:51, 25 December 2014

OCA — Thu, 25 Dec 2014 06:51:54 GMT

←Older revision		Revision as of 06:51, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 12:43, 19 November 2014

OCA — Wed, 19 Nov 2014 12:43:25 GMT

←Older revision		Revision as of 12:43, 19 November 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990==
		+	<StructureSection load='4u93' size='340' side='right' caption='[[4u93]], [[Resolution\|resolution]] 1.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4u93]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U93 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=990:(7R)-2-AMINO-7-[4-FLUORO-2-(6-METHOXYPYRIDIN-2-YL)PHENYL]-4-METHYL-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE'>990</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u93 RCSB], [http://www.ebi.ac.uk/pdbsum/4u93 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Utilizing structure-based drug design, a novel dihydropyridopyrimidinone series which exhibited potent Hsp90 inhibition, good pharmacokinetics upon oral administration, and an excellent pharmacokinetic/pharmacodynamic relationship in vivo was developed from a commercial hit. The exploration of this series led to the selection of NVP-HSP990 as a development candidate.

-	~~The entry 4u93 is ON HOLD until Paper Publication~~	+	Design, Structure-Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990.,McBride CM, Levine B, Xia Y, Bellamacina C, Machajewski T, Gao Z, Renhowe P, Antonios-McCrea W, Barsanti P, Brinner K, Costales A, Doughan B, Lin X, Louie A, McKenna M, Mendenhall K, Poon D, Rico A, Wang M, Williams TE, Abrams T, Fong S, Hendrickson T, Lei D, Lin J, Menezes D, Pryer N, Taverna P, Xu Y, Zhou Y, Shafer CM J Med Chem. 2014 Nov 13;57(21):9124-9. doi: 10.1021/jm501107q. Epub 2014 Nov 4. PMID:25368984<ref>PMID:25368984</ref>

-	~~Authors~~: Bellamacina, C.R., Shafer, C.M~~., Bussiere, D.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal Structure of Hsp90-alpha N~~-domain ~~Bound to the Inhibitor NVP-HSP990~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bellamacina, C R]]
		+	[[Category: Bussiere, D]]
		+	[[Category: Shafer, C M]]
		+	[[Category: Atp-binding domain]]
		+	[[Category: Chaperone]]

OCA at 08:49, 24 September 2014

OCA — Wed, 24 Sep 2014 08:49:30 GMT

←Older revision		Revision as of 08:49, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4u93 is ON HOLD	+	The entry 4u93 is ON HOLD until Paper Publication

	Authors: Bellamacina, C.R., Shafer, C.M., Bussiere, D.		Authors: Bellamacina, C.R., Shafer, C.M., Bussiere, D.

	Description: Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990		Description: Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990

OCA: Protected "4u93" [edit=sysop:move=sysop]

OCA — Wed, 13 Aug 2014 08:08:49 GMT

Protected "4u93" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:08, 13 August 2014

OCA: New page: '''Unreleased structure''' The entry 4u93 is ON HOLD Authors: Bellamacina, C.R., Shafer, C.M., Bussiere, D. Description: Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibito...

OCA — Wed, 13 Aug 2014 08:08:47 GMT

New page: '''Unreleased structure''' The entry 4u93 is ON HOLD Authors: Bellamacina, C.R., Shafer, C.M., Bussiere, D. Description: Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibito...

New page

'''Unreleased structure'''

The entry 4u93 is ON HOLD

Authors: Bellamacina, C.R., Shafer, C.M., Bussiere, D.

Description: Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990