4uxg - Revision history

OCA at 10:38, 10 January 2024

OCA — Wed, 10 Jan 2024 10:38:01 GMT

←Older revision		Revision as of 10:38, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UXG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UXG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [https://pdbe.org/4uxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [https://www.ebi.ac.uk/pdbsum/4uxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uxg ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [https://pdbe.org/4uxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [https://www.ebi.ac.uk/pdbsum/4uxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uxg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:49, 29 March 2023

OCA — Wed, 29 Mar 2023 07:49:20 GMT

←Older revision		Revision as of 07:49, 29 March 2023
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	<StructureSection load='4uxg' size='340' side='right'caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='4uxg' size='340' side='right'caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4UXG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UXG FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uxe\|4uxe]], [[4uxf\|4uxf]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [https://pdbe.org/4uxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [https://www.ebi.ac.uk/pdbsum/4uxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uxg ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [~~http~~://pdbe.org/4uxg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4uxg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4uxg ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/FIBP_BPT4 FIBP_BPT4]] Structural component of the proximal-half of the long-tail fiber. The long-tail fibers of T4 are about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves.<ref>PMID:8709154</ref>	+	[https://www.uniprot.org/uniprot/FIBP_BPT4 FIBP_BPT4] Structural component of the proximal-half of the long-tail fiber. The long-tail fibers of T4 are about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves.<ref>PMID:8709154</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia virus T4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Alvira, S]]	+	[[Category: Alvira S]]
-	[[Category: Garcia-Doval, C]]	+	[[Category: Garcia-Doval C]]
-	[[Category: Granell, M]]	+	[[Category: Granell M]]
-	~~[[Category: Raaij, M J.van~~]]	+	[[Category: Singh AK]]
-	[[Category: Singh~~, A K~~]]	+	[[Category: Van Raaij MJ]]
-	[[Category: ~~Caudovirale]]~~	+
-	~~[[Category: Myoviridae]]~~	+
-	~~[[Category: Triple beta-helix]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 10:52, 26 February 2020

OCA — Wed, 26 Feb 2020 10:52:53 GMT

←Older revision		Revision as of 10:52, 26 February 2020
Line 1:		Line 1:

	==Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal==		==Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal==
-	<StructureSection load='4uxg' size='340' side='right' caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='4uxg' size='340' side='right'caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXG FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Alvira, S]]		[[Category: Alvira, S]]
	[[Category: Garcia-Doval, C]]		[[Category: Garcia-Doval, C]]

OCA at 16:35, 20 October 2017

OCA — Fri, 20 Oct 2017 16:35:35 GMT

←Older revision		Revision as of 16:35, 20 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal==		==Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal==
	<StructureSection load='4uxg' size='340' side='right' caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='4uxg' size='340' side='right' caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uxe\|4uxe]], [[4uxf\|4uxf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uxe\|4uxe]], [[4uxf\|4uxf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [http://pdbe.org/4uxg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [http://www.ebi.ac.uk/pdbsum/4uxg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [http://pdbe.org/4uxg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [http://www.ebi.ac.uk/pdbsum/4uxg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uxg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
-	~~The phage-proximal part of the long~~ tail ~~fibres~~ of bacteriophage T4 ~~consists of a trimer of~~ the ~~1289 amino~~-~~acid gene product 34 (gp34)~~. ~~Different~~ carboxy-terminal ~~parts~~ of gp34 ~~have been produced and crystallized. Crystals~~ of ~~gp34(726~~-1289~~) diffracting X~~-~~rays~~ to ~~2.9 A resolution,~~ crystals of gp34~~(781~~-~~1289) diffracting to 1~~.~~9 A resolution and crystals~~ of ~~gp34(894~~-~~1289) diffracting~~ to 3.~~0 and 2.0~~ A ~~resolution and belonging~~ to ~~different crystal forms were obtained. Native data were collected for gp34~~(~~726~~-~~1289~~) and ~~gp34~~(~~894~~-~~1289~~), while ~~single~~-~~wavelength anomalous diffraction data were collected for selenomethionine~~-~~containing gp34(781-1289)~~ and ~~gp34(894~~-~~1289)~~. ~~For~~ the ~~latter, high-quality anomalous signal was obtained~~.	+	Long tail fibers of bacteriophage T4 are formed by proteins gp34, gp35, gp36, and gp37, with gp34 located at the phage-proximal end and gp37 at the phage-distal, receptor-binding end. We have solved the structure of the carboxy-terminal region of gp34, consisting of amino acids 894-1289, by single-wavelength anomalous diffraction and extended the structure to amino acids 744-1289 using data collected from crystals containing longer gp34-fragments. The structure reveals three repeats of a mixed alpha-beta fibrous domain in residues 744 to 877. A triple-helical neck connects to an extended triple beta-helix domain (amino acids 900-1127) punctuated by two beta-prism domains. Next, a beta-prism domain decorated with short helices and extended beta-helices is present (residues 1146-1238), while the C-terminal end is capped with another short beta-helical region and three beta-hairpins. The structure provides insight into the stability of the fibrous gp34 protein.

-	~~Crystallization~~ of the ~~carboxy~~-~~terminal region~~ of the ~~bacteriophage~~ T4 ~~proximal long tail fibre protein gp34~~.,Granell M, Namura M, Alvira S, ~~Garcia-Doval C, Singh AK, Gutsche I~~, van Raaij MJ~~, Kanamaru S Acta Crystallogr F Struct Biol Commun~~. ~~2014 Jul~~;70(Pt 7):~~970-5~~. doi:, 10.~~1107~~/~~S2053230X14010449. Epub 2014 Jun 19~~. PMID:~~25005101~~<ref>PMID:~~25005101~~</ref>	+	Crystal Structure of the Carboxy-Terminal Region of the Bacteriophage T4 Proximal Long Tail Fiber Protein Gp34.,Granell M, Namura M, Alvira S, Kanamaru S, van Raaij MJ Viruses. 2017 Jun 30;9(7). pii: E168. doi: 10.3390/v9070168. PMID:28665339<ref>PMID:28665339</ref>

	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

OCA at 14:31, 30 September 2015

OCA — Wed, 30 Sep 2015 14:31:02 GMT

←Older revision		Revision as of 14:31, 30 September 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal==
		+	<StructureSection load='4uxg' size='340' side='right' caption='[[4uxg]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4uxg]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXG FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uxe\|4uxe]], [[4uxf\|4uxf]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxg OCA], [http://pdbe.org/4uxg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uxg RCSB], [http://www.ebi.ac.uk/pdbsum/4uxg PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FIBP_BPT4 FIBP_BPT4]] Structural component of the proximal-half of the long-tail fiber. The long-tail fibers of T4 are about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves.<ref>PMID:8709154</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The phage-proximal part of the long tail fibres of bacteriophage T4 consists of a trimer of the 1289 amino-acid gene product 34 (gp34). Different carboxy-terminal parts of gp34 have been produced and crystallized. Crystals of gp34(726-1289) diffracting X-rays to 2.9 A resolution, crystals of gp34(781-1289) diffracting to 1.9 A resolution and crystals of gp34(894-1289) diffracting to 3.0 and 2.0 A resolution and belonging to different crystal forms were obtained. Native data were collected for gp34(726-1289) and gp34(894-1289), while single-wavelength anomalous diffraction data were collected for selenomethionine-containing gp34(781-1289) and gp34(894-1289). For the latter, high-quality anomalous signal was obtained.

-	~~The entry 4uxg is ON HOLD until Paper Publication~~	+	Crystallization of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34.,Granell M, Namura M, Alvira S, Garcia-Doval C, Singh AK, Gutsche I, van Raaij MJ, Kanamaru S Acta Crystallogr F Struct Biol Commun. 2014 Jul;70(Pt 7):970-5. doi:, 10.1107/S2053230X14010449. Epub 2014 Jun 19. PMID:25005101<ref>PMID:25005101</ref>

-	~~Authors: Granell~~, M.~~, Alvira,~~ S.~~, Garcia-Doval, C., Singh, A.K., van Raaij, M.J~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34~~, ~~R32 native crystal~~	+	<div class="pdbe-citations 4uxg" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Alvira, S]]
		+	[[Category: Garcia-Doval, C]]
	[[Category: Granell, M]]		[[Category: Granell, M]]
-	[[Category: ~~Garcia-Doval~~, C]]	+	[[Category: Raaij, M J.van]]
-	[[Category: ~~Van Raaij~~, ~~M.J~~]]	+	[[Category: Singh, A K]]
-	[[Category: ~~Alvira, S~~]]	+	[[Category: Caudovirale]]
-	[[Category: ~~Singh, A.K~~]]	+	[[Category: Myoviridae]]
		+	[[Category: Triple beta-helix]]
		+	[[Category: Viral protein]]

OCA at 18:51, 24 December 2014

OCA — Wed, 24 Dec 2014 18:51:19 GMT

←Older revision		Revision as of 18:51, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal		Description: Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal
		+	[[Category: Unreleased Structures]]
		+	[[Category: Granell, M]]
		+	[[Category: Garcia-Doval, C]]
		+	[[Category: Van Raaij, M.J]]
		+	[[Category: Alvira, S]]
		+	[[Category: Singh, A.K]]

OCA: Protected "4uxg" [edit=sysop:move=sysop]

OCA — Thu, 04 Sep 2014 04:41:03 GMT

Protected "4uxg" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:41, 4 September 2014

OCA: New page: '''Unreleased structure''' The entry 4uxg is ON HOLD until Paper Publication Authors: Granell, M., Alvira, S., Garcia-Doval, C., Singh, A.K., van Raaij, M.J. Description: Crystal struc...

OCA — Thu, 04 Sep 2014 04:41:02 GMT

New page: '''Unreleased structure''' The entry 4uxg is ON HOLD until Paper Publication Authors: Granell, M., Alvira, S., Garcia-Doval, C., Singh, A.K., van Raaij, M.J. Description: Crystal struc...

New page

'''Unreleased structure'''

The entry 4uxg is ON HOLD until Paper Publication

Authors: Granell, M., Alvira, S., Garcia-Doval, C., Singh, A.K., van Raaij, M.J.

Description: Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, R32 native crystal