4w4m - Revision history

OCA at 00:51, 28 December 2023

OCA — Thu, 28 Dec 2023 00:51:14 GMT

←Older revision		Revision as of 00:51, 28 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4W4M FirstGlance]. <br>		<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4W4M FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [https://pdbe.org/4w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [https://www.ebi.ac.uk/pdbsum/4w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4w4m ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [https://pdbe.org/4w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [https://www.ebi.ac.uk/pdbsum/4w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4w4m ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:16, 29 March 2023

OCA — Wed, 29 Mar 2023 08:16:43 GMT

←Older revision		Revision as of 08:16, 29 March 2023
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	<StructureSection load='4w4m' size='340' side='right'caption='[[4w4m]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='4w4m' size='340' side='right'caption='[[4w4m]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Salty Salty~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4W4M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4W4M FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">prgK, STM2871 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [https://pdbe.org/4w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [https://www.ebi.ac.uk/pdbsum/4w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4w4m ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [~~http~~://pdbe.org/4w4m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4w4m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4w4m ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PRGK_SALTY PRGK_SALTY]] Required for invasion of epithelial cells. Could be involved in protein secretion.	+	[https://www.uniprot.org/uniprot/PRGK_SALTY PRGK_SALTY] Required for invasion of epithelial cells. Could be involved in protein secretion.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Salty~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-	[[Category: Bergeron~~, J R.C~~]]	+	[[Category: Bergeron JRC]]
-	[[Category: Strynadka~~, N C.J]]~~	+	[[Category: Strynadka NCJ]]
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Salmonella]]~~	+
-	~~[[Category: T3ss~~]]	+

OCA at 08:56, 23 May 2019

OCA — Thu, 23 May 2019 08:56:00 GMT

←Older revision		Revision as of 08:56, 23 May 2019
Line 1:		Line 1:
		+
	==Crystal structure of PrgK 19-92==		==Crystal structure of PrgK 19-92==
-	<StructureSection load='4w4m' size='340' side='right' caption='[[4w4m]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='4w4m' size='340' side='right'caption='[[4w4m]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W4M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W4M FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [http://www.ebi.ac.uk/pdbsum/4w4m PDBsum]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">prgK, STM2871 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [http://pdbe.org/4w4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [http://www.ebi.ac.uk/pdbsum/4w4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4w4m ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4w4m" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Salty]]
	[[Category: Bergeron, J R.C]]		[[Category: Bergeron, J R.C]]
	[[Category: Strynadka, N C.J]]		[[Category: Strynadka, N C.J]]

OCA at 07:51, 14 January 2015

OCA — Wed, 14 Jan 2015 07:51:19 GMT

←Older revision		Revision as of 07:51, 14 January 2015
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/PRGK_SALTY PRGK_SALTY]] Required for invasion of epithelial cells. Could be involved in protein secretion.		[[http://www.uniprot.org/uniprot/PRGK_SALTY PRGK_SALTY]] Required for invasion of epithelial cells. Could be involved in protein secretion.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The type III secretion system (T3SS) is a large macromolecular assembly found at the surface of many pathogenic Gram-negative bacteria. Its role is to inject toxic "effector" proteins into the cells of infected organisms. The molecular details of the assembly of this large, multimembrane-spanning complex remain poorly understood. Here, we report structural, biochemical, and functional analyses of PrgK, an inner-membrane component of the prototypical Salmonella typhimurium T3SS. We have obtained the atomic structures of the two ring building globular domains and show that the C-terminal transmembrane helix is not essential for assembly and secretion. We also demonstrate that structural rearrangement of the two PrgK globular domains, driven by an interconnecting linker region, may promote oligomerization into ring structures. Finally, we used electron microscopy-guided symmetry modeling to propose a structural model for the intimately associated PrgH-PrgK ring interaction within the assembled basal body.
		+
		+	The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body.,Bergeron JR, Worrall LJ, De S, Sgourakis NG, Cheung AH, Lameignere E, Okon M, Wasney GA, Baker D, McIntosh LP, Strynadka NC Structure. 2015 Jan 6;23(1):161-72. doi: 10.1016/j.str.2014.10.021. Epub 2014 Dec, 18. PMID:25533490<ref>PMID:25533490</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 20:46, 25 December 2014

OCA — Thu, 25 Dec 2014 20:46:47 GMT

←Older revision		Revision as of 20:46, 25 December 2014
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	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [http://www.ebi.ac.uk/pdbsum/4w4m PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [http://www.ebi.ac.uk/pdbsum/4w4m PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PRGK_SALTY PRGK_SALTY]] Required for invasion of epithelial cells. Could be involved in protein secretion.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bergeron, J R.C.]]	+	[[Category: Bergeron, J R.C]]
-	[[Category: Strynadka, N C.J.]]	+	[[Category: Strynadka, N C.J]]
	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Salmonella]]		[[Category: Salmonella]]
	[[Category: T3ss]]		[[Category: T3ss]]

OCA at 11:33, 29 October 2014

OCA — Wed, 29 Oct 2014 11:33:44 GMT

←Older revision		Revision as of 11:33, 29 October 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of PrgK 19-92==
-		+	<StructureSection load='4w4m' size='340' side='right' caption='[[4w4m]], [[Resolution\|resolution]] 3.20Å' scene=''>
-	~~The entry~~ 4w4m is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4w4m]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W4M FirstGlance]. <br>
-	~~Authors~~: Bergeron, J.R.C., Strynadka, N.C.J.	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w4m RCSB], [http://www.ebi.ac.uk/pdbsum/4w4m PDBsum]</span></td></tr>
-		+	</table>
-	~~Description~~:	+	__TOC__
		+	</StructureSection>
		+	[[Category: Bergeron, J R.C.]]
		+	[[Category: Strynadka, N C.J.]]
		+	[[Category: Protein transport]]
		+	[[Category: Salmonella]]
		+	[[Category: T3ss]]

OCA at 06:48, 8 October 2014

OCA — Wed, 08 Oct 2014 06:48:28 GMT

←Older revision		Revision as of 06:48, 8 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4w4m is ON HOLD	+	The entry 4w4m is ON HOLD until Paper Publication

	Authors: Bergeron, J.R.C., Strynadka, N.C.J.		Authors: Bergeron, J.R.C., Strynadka, N.C.J.

	Description:		Description:

OCA at 07:26, 27 August 2014

OCA — Wed, 27 Aug 2014 07:26:34 GMT

←Older revision		Revision as of 07:26, 27 August 2014
Line 3:		Line 3:
	The entry 4w4m is ON HOLD		The entry 4w4m is ON HOLD

-	Authors: ~~Julien~~ R.C. ~~Bergeron~~, ~~Natalie~~ C.J. ~~Strynadka~~	+	Authors: Bergeron, J.R.C., Strynadka, N.C.J.

	Description:		Description:

OCA: Protected "4w4m" [edit=sysop:move=sysop]

OCA — Wed, 20 Aug 2014 15:16:22 GMT

Protected "4w4m" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:16, 20 August 2014

OCA: New page: '''Unreleased structure''' The entry 4w4m is ON HOLD Authors: Julien R.C. Bergeron, Natalie C.J. Strynadka Description:

OCA — Wed, 20 Aug 2014 15:16:21 GMT

New page: '''Unreleased structure''' The entry 4w4m is ON HOLD Authors: Julien R.C. Bergeron, Natalie C.J. Strynadka Description:

New page

'''Unreleased structure'''

The entry 4w4m is ON HOLD

Authors: Julien R.C. Bergeron, Natalie C.J. Strynadka

Description: