4wbd - Revision history

OCA at 00:52, 28 December 2023

OCA — Thu, 28 Dec 2023 00:52:24 GMT

←Older revision		Revision as of 00:52, 28 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WBD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.77Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [https://pdbe.org/4wbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [https://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [https://pdbe.org/4wbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [https://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:00, 7 April 2023

OCA — Fri, 07 Apr 2023 07:00:41 GMT

←Older revision		Revision as of 07:00, 7 April 2023
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	<StructureSection load='4wbd' size='340' side='right'caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>		<StructureSection load='4wbd' size='340' side='right'caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bacsu Bacsu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WBD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WBD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yllA, BSU15120 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [https://pdbe.org/4wbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [https://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [~~http~~://pdbe.org/4wbd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/BSHC_BACSU BSHC_BACSU] Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.[HAMAP-Rule:MF_01867]<ref>PMID:20308541</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacsu~~]]	+	[[Category: Bacillus subtilis subsp. subtilis str. 168]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cook~~, P D~~]]	+	[[Category: Cook PD]]
-	[[Category: VanDuinen~~, A J~~]]	+	[[Category: VanDuinen AJ]]
-	[[Category: Winchell~~, K R]]~~	+	[[Category: Winchell KR]]
-	~~[[Category: Bacililthiol]]~~	+
-	~~[[Category: Cysteine]]~~	+
-	~~[[Category: Ligase]]~~	+
-	~~[[Category: Rossmann~~]]	+

OCA at 10:28, 25 December 2019

OCA — Wed, 25 Dec 2019 10:28:43 GMT

←Older revision		Revision as of 10:28, 25 December 2019
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	<StructureSection load='4wbd' size='340' side='right'caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>		<StructureSection load='4wbd' size='340' side='right'caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yllA, BSU15120 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [http://pdbe.org/4wbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [http://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [http://pdbe.org/4wbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [http://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacsu]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cook, P D]]		[[Category: Cook, P D]]

OCA at 07:24, 10 July 2019

OCA — Wed, 10 Jul 2019 07:24:06 GMT

←Older revision		Revision as of 07:24, 10 July 2019
Line 1:		Line 1:

	==The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP==		==The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP==
-	<StructureSection load='4wbd' size='340' side='right' caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>	+	<StructureSection load='4wbd' size='340' side='right'caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Cook, P D]]		[[Category: Cook, P D]]
	[[Category: VanDuinen, A J]]		[[Category: VanDuinen, A J]]

OCA at 13:07, 11 August 2016

OCA — Thu, 11 Aug 2016 13:07:16 GMT

←Older revision		Revision as of 13:07, 11 August 2016
Line 1:		Line 1:
		+
	==The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP==		==The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP==
	<StructureSection load='4wbd' size='340' side='right' caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>		<StructureSection load='4wbd' size='340' side='right' caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [http://www.ebi.ac.uk/pdbsum/4wbd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [http://pdbe.org/4wbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [http://www.ebi.ac.uk/pdbsum/4wbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wbd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4wbd" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:48, 31 December 2014

OCA — Wed, 31 Dec 2014 14:48:00 GMT

←Older revision		Revision as of 14:48, 31 December 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP==
		+	<StructureSection load='4wbd' size='340' side='right' caption='[[4wbd]], [[Resolution\|resolution]] 1.77Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4wbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WBD FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wbd RCSB], [http://www.ebi.ac.uk/pdbsum/4wbd PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacillithiol is produced by many Gram-positive bacteria via a pathway utilizing the enzymes BshA, BshB, and BshC. Here we report the 1.77 A resolution crystal structure of BshC, the putative cysteine ligase in bacillithiol production. The structure reveals that BshC contains a core Rossmann fold with connecting peptide motifs (CP1 and CP2) and a unique alpha-helical coiled-coil domain that facilitates dimerization. The model contains citrate and glycerol in the canonical active site and ADP in a second binding pocket. The overall structure and bound ligands give insight into the function of this unique enzyme.

-	~~The entry 4wbd is ON HOLD until Paper Publication~~	+	X-ray Crystallographic Structure of BshC, a Unique Enzyme Involved in Bacillithiol Biosynthesis.,VanDuinen AJ, Winchell KR, Keithly ME, Cook PD Biochemistry. 2014 Dec 18. PMID:25496067<ref>PMID:25496067</ref>

-	~~Authors: Cook~~, P.D.~~, VanDuinen, A.J., Winchell, K.R~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: ~~Vanduinen~~, A.J]]	+	__TOC__
-	[[Category: Winchell, K.R]]	+	</StructureSection>
-	[[Category: ~~Cook, P.D~~]]	+	[[Category: Cook, P D]]
		+	[[Category: VanDuinen, A J]]
		+	[[Category: Winchell, K R]]
		+	[[Category: Bacililthiol]]
		+	[[Category: Cysteine]]
		+	[[Category: Ligase]]
		+	[[Category: Rossmann]]

OCA at 19:17, 24 December 2014

OCA — Wed, 24 Dec 2014 19:17:24 GMT

←Older revision		Revision as of 19:17, 24 December 2014
Line 6:		Line 6:

	Description: The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP		Description: The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP
		+	[[Category: Unreleased Structures]]
		+	[[Category: Vanduinen, A.J]]
		+	[[Category: Winchell, K.R]]
		+	[[Category: Cook, P.D]]

OCA at 23:28, 1 October 2014

OCA — Wed, 01 Oct 2014 23:28:48 GMT

←Older revision		Revision as of 23:28, 1 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4wbd is ON HOLD	+	The entry 4wbd is ON HOLD until Paper Publication

	Authors: Cook, P.D., VanDuinen, A.J., Winchell, K.R.		Authors: Cook, P.D., VanDuinen, A.J., Winchell, K.R.

	Description: The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP		Description: The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP

OCA: Protected "4wbd" [edit=sysop:move=sysop]

OCA — Wed, 10 Sep 2014 08:55:15 GMT

Protected "4wbd" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:55, 10 September 2014

OCA: New page: '''Unreleased structure''' The entry 4wbd is ON HOLD Authors: Cook, P.D., VanDuinen, A.J., Winchell, K.R. Description: The crystal structure of BshC from Bacillus subtilis complexed wi...

OCA — Wed, 10 Sep 2014 08:55:13 GMT

New page: '''Unreleased structure''' The entry 4wbd is ON HOLD Authors: Cook, P.D., VanDuinen, A.J., Winchell, K.R. Description: The crystal structure of BshC from Bacillus subtilis complexed wi...

New page

'''Unreleased structure'''

The entry 4wbd is ON HOLD

Authors: Cook, P.D., VanDuinen, A.J., Winchell, K.R.

Description: The crystal structure of BshC from Bacillus subtilis complexed with citrate and ADP