4wkh - Revision history

OCA at 10:43, 10 January 2024

OCA — Wed, 10 Jan 2024 10:43:32 GMT

←Older revision		Revision as of 10:43, 10 January 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WKH FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WKH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.05Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [https://pdbe.org/4wkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [https://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [https://pdbe.org/4wkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [https://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:13, 7 April 2023

OCA — Fri, 07 Apr 2023 07:13:00 GMT

←Older revision		Revision as of 07:13, 7 April 2023
Line 3:		Line 3:
	<StructureSection load='4wkh' size='340' side='right'caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>		<StructureSection load='4wkh' size='340' side='right'caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WKH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WKH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~CBS~~:~~DI(~~N-ACETYL-D-GLUCOSAMINE)'>~~CBS~~</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1guv\|1guv]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [https://pdbe.org/4wkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [https://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [~~http~~://pdbe.org/4wkh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN]] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref>	+	[https://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chitinase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cachau, R]]	+	[[Category: Cachau R]]
-	[[Category: Cousido-Siah, A]]	+	[[Category: Cousido-Siah A]]
-	[[Category: Fadel, F]]	+	[[Category: Fadel F]]
-	[[Category: Harlos, K]]	+	[[Category: Harlos K]]
-	[[Category: Howard, E]]	+	[[Category: Howard E]]
-	[[Category: Mitschler, A]]	+	[[Category: Mitschler A]]
-	[[Category: Podjarny, A]]	+	[[Category: Podjarny A]]
-	[[Category: Ruiz~~, F X~~]]	+	[[Category: Ruiz FX]]
-	[[Category: Zhao, Y]]	+	[[Category: Zhao Y]]
-	~~[[Category: Catalytic mechanism]]~~	+
-	~~[[Category: Chit1]]~~	+
-	~~[[Category: Gh18 chitinase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolysis]]~~	+
-	~~[[Category: Protonation state~~]]	+

OCA at 08:18, 23 May 2019

OCA — Thu, 23 May 2019 08:18:15 GMT

←Older revision		Revision as of 08:18, 23 May 2019
Line 1:		Line 1:

	==Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution==		==Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution==
-	<StructureSection load='4wkh' size='340' side='right' caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>	+	<StructureSection load='4wkh' size='340' side='right'caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WKH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WKH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBS:DI(N-ACETYL-D-GLUCOSAMINE)'>CBS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBS:DI(N-ACETYL-D-GLUCOSAMINE)'>CBS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1guv\|1guv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1guv\|1guv]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [http://pdbe.org/4wkh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [http://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [http://pdbe.org/4wkh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [http://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>
Line 22:		Line 23:

	==See Also==		==See Also==
-	*[[Chitinase\|Chitinase]]	+	*[[Chitinase 3D structures\|Chitinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Chitinase]]		[[Category: Chitinase]]
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Cachau, R]]		[[Category: Cachau, R]]
	[[Category: Cousido-Siah, A]]		[[Category: Cousido-Siah, A]]

OCA at 14:18, 27 April 2017

OCA — Thu, 27 Apr 2017 14:18:17 GMT

←Older revision		Revision as of 14:18, 27 April 2017
Line 1:		Line 1:
		+
	==Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution==		==Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution==
	<StructureSection load='4wkh' size='340' side='right' caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>		<StructureSection load='4wkh' size='340' side='right' caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1guv\|1guv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1guv\|1guv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [http://www.ebi.ac.uk/pdbsum/4wkh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [http://pdbe.org/4wkh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [http://www.ebi.ac.uk/pdbsum/4wkh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wkh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4wkh" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Chitinase\|Chitinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:11, 22 July 2015

OCA — Wed, 22 Jul 2015 08:11:56 GMT

←Older revision		Revision as of 08:11, 22 July 2015
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN]] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref>		[[http://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN]] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Chitotriosidase (CHIT1) is a human chitinase belonging to the highly conserved glycosyl hydrolase family 18 (GH18). GH18 enzymes hydrolyze chitin, an N-acetylglucosamine polymer synthesized by lower organisms for structural purposes. Recently, CHIT1 has attracted attention owing to its upregulation in immune-system disorders and as a marker of Gaucher disease. The 39 kDa catalytic domain shows a conserved cluster of three acidic residues, Glu140, Asp138 and Asp136, involved in the hydrolysis reaction. Under an excess concentration of substrate, CHIT1 and other homologues perform an additional activity, transglycosylation. To understand the catalytic mechanism of GH18 chitinases and the dual enzymatic activity, the structure and mechanism of CHIT1 were analyzed in detail. The resolution of the crystals of the catalytic domain was improved from 1.65 A (PDB entry 1waw) to 0.95-1.10 A for the apo and pseudo-apo forms and the complex with chitobiose, allowing the determination of the protonation states within the active site. This information was extended by hybrid quantum mechanics/molecular mechanics (QM/MM) calculations. The results suggest a new mechanism involving changes in the conformation and protonation state of the catalytic triad, as well as a new role for Tyr27, providing new insights into the hydrolysis and transglycosylation activities.
		+
		+	New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.,Fadel F, Zhao Y, Cachau R, Cousido-Siah A, Ruiz FX, Harlos K, Howard E, Mitschler A, Podjarny A Acta Crystallogr D Biol Crystallogr. 2015 Jul 1;71(Pt 7):1455-70. doi:, 10.1107/S139900471500783X. Epub 2015 Jun 30. PMID:26143917<ref>PMID:26143917</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:52, 8 July 2015

OCA — Wed, 08 Jul 2015 14:52:52 GMT

←Older revision		Revision as of 14:52, 8 July 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution==
-		+	<StructureSection load='4wkh' size='340' side='right' caption='[[4wkh]], [[Resolution\|resolution]] 1.05Å' scene=''>
-	~~The entry~~ 4wkh is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4wkh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WKH FirstGlance]. <br>
-	~~Authors~~: ~~Fadel, F~~.~~, Zhao, Y~~.~~, Cachau, R~~.~~, Cousido~~-~~Siah, A~~.~~, Ruiz, F~~.X.~~, Harlos, K~~.~~, Howard, E~~.~~, Mitschler, A., Podjarny, A~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBS:DI(N-ACETYL-D-GLUCOSAMINE)'>CBS</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1guv\|1guv]]</td></tr>
-	~~Description~~: ~~Crystal structure of human chitotriosidase~~-1 ~~catalytic domain in complex with chitobiose (1mM) at~~ 1.~~05 A resolution~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wkh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wkh RCSB], [http://www.ebi.ac.uk/pdbsum/4wkh PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Fadel, F~~]]	+	</table>
-	[[Category: ~~Podjarny, A~~]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CHIT1_HUMAN CHIT1_HUMAN]] Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<ref>PMID:7592832</ref> <ref>PMID:7836450</ref> <ref>PMID:9748235</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Chitinase]]
	[[Category: Cachau, R]]		[[Category: Cachau, R]]
-	[[Category: Mitschler, A]]
-	[[Category: Harlos, K]]
-	[[Category: Zhao, Y]]
	[[Category: Cousido-Siah, A]]		[[Category: Cousido-Siah, A]]
		+	[[Category: Fadel, F]]
		+	[[Category: Harlos, K]]
	[[Category: Howard, E]]		[[Category: Howard, E]]
-	[[Category: Ruiz, F.X]]	+	[[Category: Mitschler, A]]
		+	[[Category: Podjarny, A]]
		+	[[Category: Ruiz, F X]]
		+	[[Category: Zhao, Y]]
		+	[[Category: Catalytic mechanism]]
		+	[[Category: Chit1]]
		+	[[Category: Gh18 chitinase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolysis]]
		+	[[Category: Protonation state]]

OCA at 19:37, 24 December 2014

OCA — Wed, 24 Dec 2014 19:37:00 GMT

←Older revision		Revision as of 19:37, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution		Description: Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution
		+	[[Category: Unreleased Structures]]
		+	[[Category: Fadel, F]]
		+	[[Category: Podjarny, A]]
		+	[[Category: Cachau, R]]
		+	[[Category: Mitschler, A]]
		+	[[Category: Harlos, K]]
		+	[[Category: Zhao, Y]]
		+	[[Category: Cousido-Siah, A]]
		+	[[Category: Howard, E]]
		+	[[Category: Ruiz, F.X]]

OCA at 09:55, 20 October 2014

OCA — Mon, 20 Oct 2014 09:55:26 GMT

←Older revision		Revision as of 09:55, 20 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4wkh is ON HOLD	+	The entry 4wkh is ON HOLD until Paper Publication

	Authors: Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.		Authors: Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.

	Description: Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution		Description: Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution

OCA: Protected "4wkh" [edit=sysop:move=sysop]

OCA — Wed, 08 Oct 2014 06:59:28 GMT

Protected "4wkh" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:59, 8 October 2014

OCA: New page: '''Unreleased structure''' The entry 4wkh is ON HOLD Authors: Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A. Descrip...

OCA — Wed, 08 Oct 2014 06:59:27 GMT

New page: '''Unreleased structure''' The entry 4wkh is ON HOLD Authors: Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A. Descrip...

New page

'''Unreleased structure'''

The entry 4wkh is ON HOLD

Authors: Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.

Description: Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution