4wqs - Revision history

OCA at 09:01, 20 March 2024

OCA — Wed, 20 Mar 2024 09:01:55 GMT

←Older revision		Revision as of 09:01, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 4.306Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [https://pdbe.org/4wqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [https://www.ebi.ac.uk/pdbsum/4wqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wqs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [https://pdbe.org/4wqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [https://www.ebi.ac.uk/pdbsum/4wqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wqs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/RPOA_THET8 RPOA_THET8] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.		[https://www.uniprot.org/uniprot/RPOA_THET8 RPOA_THET8] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	DNA-dependent RNA polymerase (RNAP) accomplishes multiple tasks during transcription by assuming different structural forms. Reportedly, the "tight" form performs nucleotide addition to nascent RNA, while the "ratcheted" form is adopted for transcription inhibition. In this study, we performed Cys-pair crosslinking (CPX) analyses of various transcription complexes of a bacterial RNAP and crystallographic analyses of its backtracked and Gre-factor-bound states to clarify which of the two forms is adopted. The ratcheted form was revealed to support GreA-dependent transcript cleavage, long backtracking, hairpin-dependent pausing, and termination. In contrast, the tight form correlated with nucleotide addition, mismatch-dependent pausing, one-nucleotide backtracking, and factor-independent transcript cleavage. RNAP in the paused/backtracked state, but not the nucleotide-addition state, readily transitions to the ratcheted form ("ratchetable"), indicating that the tight form represents two distinct regulatory states. The 3' end and the hairpin structure of the nascent RNA promote the ratchetable nature by modulating the trigger-loop conformation.
-
-	The ratcheted and ratchetable structural States of RNA polymerase underlie multiple transcriptional functions.,Sekine S, Murayama Y, Svetlov V, Nudler E, Yokoyama S Mol Cell. 2015 Feb 5;57(3):408-21. doi: 10.1016/j.molcel.2014.12.014. Epub 2015, Jan 15. PMID:25601758<ref>PMID:25601758</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4wqs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]		*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:21, 7 April 2023

OCA — Fri, 07 Apr 2023 07:21:25 GMT

←Older revision		Revision as of 07:21, 7 April 2023
Line 3:		Line 3:
	<StructureSection load='4wqs' size='340' side='right'caption='[[4wqs]], [[Resolution\|resolution]] 4.31Å' scene=''>		<StructureSection load='4wqs' size='340' side='right'caption='[[4wqs]], [[Resolution\|resolution]] 4.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8~~ Thermus thermophilus ~~hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WQS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aoh\|3aoh]], [[3aoi\|3aoi]], [[4wqt\|4wqt]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [https://pdbe.org/4wqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [https://www.ebi.ac.uk/pdbsum/4wqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wqs ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [~~http~~://pdbe.org/4wqs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wqs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wqs ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/RPOZ_THET8 RPOZ_THET8]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). [[http://www.uniprot.org/uniprot/RPOA_THET8 RPOA_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOC_THET8 RPOC_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOB_THET8 RPOB_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	+	[https://www.uniprot.org/uniprot/RPOA_THET8 RPOA_THET8] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[RNA polymerase\|RNA polymerase]]	+	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: DNA-directed RNA polymerase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Thermus thermophilus ~~hb8~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: ~~Murayama, Y~~]]	+	[[Category: Unidentified]]
-	[[Category: ~~Sekine, S~~]]	+	[[Category: Murayama Y]]
-	[[Category: ~~Yokoyama,~~ S]]	+	[[Category: Sekine S]]
-	[[Category: ~~Rna cleavage]]~~	+	[[Category: Yokoyama S]]
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transferase-dna-rna complex~~]]	+

OCA at 09:12, 23 May 2019

OCA — Thu, 23 May 2019 09:12:08 GMT

←Older revision		Revision as of 09:12, 23 May 2019
Line 1:		Line 1:
		+
	==Thermus thermophilus RNA polymerase backtracked complex==		==Thermus thermophilus RNA polymerase backtracked complex==
-	<StructureSection load='4wqs' size='340' side='right' caption='[[4wqs]], [[Resolution\|resolution]] 4.31Å' scene=''>	+	<StructureSection load='4wqs' size='340' side='right'caption='[[4wqs]], [[Resolution\|resolution]] 4.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQS FirstGlance]. <br>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aoh\|3aoh]], [[3aoi\|3aoi]], [[4wqt\|4wqt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aoh\|3aoh]], [[3aoi\|3aoi]], [[4wqt\|4wqt]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [http://pdbe.org/4wqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [http://www.ebi.ac.uk/pdbsum/4wqs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [http://pdbe.org/4wqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [http://www.ebi.ac.uk/pdbsum/4wqs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wqs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 23:
	==See Also==		==See Also==
	*[[RNA polymerase\|RNA polymerase]]		*[[RNA polymerase\|RNA polymerase]]
-	*[[Temp1\|Temp1]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: DNA-directed RNA polymerase]]		[[Category: DNA-directed RNA polymerase]]
		+	[[Category: Large Structures]]
	[[Category: Thermus thermophilus hb8]]		[[Category: Thermus thermophilus hb8]]
	[[Category: Murayama, Y]]		[[Category: Murayama, Y]]

OCA at 08:13, 30 September 2015

OCA — Wed, 30 Sep 2015 08:13:52 GMT

←Older revision		Revision as of 08:13, 30 September 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aoh\|3aoh]], [[3aoi\|3aoi]], [[4wqt\|4wqt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aoh\|3aoh]], [[3aoi\|3aoi]], [[4wqt\|4wqt]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [http://www.ebi.ac.uk/pdbsum/4wqs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [http://pdbe.org/4wqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [http://www.ebi.ac.uk/pdbsum/4wqs PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4wqs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 05:06, 9 September 2015

OCA — Wed, 09 Sep 2015 05:06:24 GMT

←Older revision		Revision as of 05:06, 9 September 2015
Line 18:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[RNA polymerase\|RNA polymerase]]
		+	*[[Temp1\|Temp1]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:02, 18 February 2015

OCA — Wed, 18 Feb 2015 13:02:50 GMT

←Older revision		Revision as of 13:02, 18 February 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Thermus thermophilus RNA polymerase backtracked complex==
		+	<StructureSection load='4wqs' size='340' side='right' caption='[[4wqs]], [[Resolution\|resolution]] 4.31Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4wqs]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aoh\|3aoh]], [[3aoi\|3aoi]], [[4wqt\|4wqt]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wqs RCSB], [http://www.ebi.ac.uk/pdbsum/4wqs PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RPOZ_THET8 RPOZ_THET8]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). [[http://www.uniprot.org/uniprot/RPOA_THET8 RPOA_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOC_THET8 RPOC_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOB_THET8 RPOB_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DNA-dependent RNA polymerase (RNAP) accomplishes multiple tasks during transcription by assuming different structural forms. Reportedly, the "tight" form performs nucleotide addition to nascent RNA, while the "ratcheted" form is adopted for transcription inhibition. In this study, we performed Cys-pair crosslinking (CPX) analyses of various transcription complexes of a bacterial RNAP and crystallographic analyses of its backtracked and Gre-factor-bound states to clarify which of the two forms is adopted. The ratcheted form was revealed to support GreA-dependent transcript cleavage, long backtracking, hairpin-dependent pausing, and termination. In contrast, the tight form correlated with nucleotide addition, mismatch-dependent pausing, one-nucleotide backtracking, and factor-independent transcript cleavage. RNAP in the paused/backtracked state, but not the nucleotide-addition state, readily transitions to the ratcheted form ("ratchetable"), indicating that the tight form represents two distinct regulatory states. The 3' end and the hairpin structure of the nascent RNA promote the ratchetable nature by modulating the trigger-loop conformation.

-	The ~~entry 4wqs is ON HOLD until Paper Publication~~	+	The ratcheted and ratchetable structural States of RNA polymerase underlie multiple transcriptional functions.,Sekine S, Murayama Y, Svetlov V, Nudler E, Yokoyama S Mol Cell. 2015 Feb 5;57(3):408-21. doi: 10.1016/j.molcel.2014.12.014. Epub 2015, Jan 15. PMID:25601758<ref>PMID:25601758</ref>

-	~~Authors: Murayama~~, Y.~~, Sekine,~~ S.~~, Yokoyama, S~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~:	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: DNA-directed RNA polymerase]]
		+	[[Category: Thermus thermophilus hb8]]
	[[Category: Murayama, Y]]		[[Category: Murayama, Y]]
	[[Category: Sekine, S]]		[[Category: Sekine, S]]
	[[Category: Yokoyama, S]]		[[Category: Yokoyama, S]]
		+	[[Category: Rna cleavage]]
		+	[[Category: Transcription]]
		+	[[Category: Transferase-dna-rna complex]]

OCA at 19:52, 24 December 2014

OCA — Wed, 24 Dec 2014 19:52:32 GMT

←Older revision		Revision as of 19:52, 24 December 2014
Line 5:		Line 5:
	Authors: Murayama, Y., Sekine, S., Yokoyama, S.		Authors: Murayama, Y., Sekine, S., Yokoyama, S.

-	Description:	+	Description:
		+	[[Category: Unreleased Structures]]
		+	[[Category: Murayama, Y]]
		+	[[Category: Sekine, S]]
		+	[[Category: Yokoyama, S]]

OCA at 14:08, 10 December 2014

OCA — Wed, 10 Dec 2014 14:08:01 GMT

←Older revision		Revision as of 14:08, 10 December 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4wqs is ON HOLD	+	The entry 4wqs is ON HOLD until Paper Publication

-	Authors: Murayama, Y., Sekine, S., Yokoyama, S.~~, RIKEN Structural Genomics/Proteomics Initiative (RSGI)~~	+	Authors: Murayama, Y., Sekine, S., Yokoyama, S.

	Description:		Description:

OCA at 11:55, 19 November 2014

OCA — Wed, 19 Nov 2014 11:55:23 GMT

←Older revision		Revision as of 11:55, 19 November 2014
Line 3:		Line 3:
	The entry 4wqs is ON HOLD		The entry 4wqs is ON HOLD

-	Authors: Murayama, Y., Sekine, S., Yokoyama, S.	+	Authors: Murayama, Y., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

	Description:		Description:

OCA: Protected "4wqs" [edit=sysop:move=sysop]

OCA — Wed, 29 Oct 2014 10:35:56 GMT

Protected "4wqs" [edit=sysop:move=sysop]

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Revision as of 10:35, 29 October 2014