4x2m - Revision history

OCA at 21:07, 12 April 2023

OCA — Wed, 12 Apr 2023 21:07:50 GMT

←Older revision		Revision as of 21:07, 12 April 2023
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	<StructureSection load='4x2m' size='340' side='right'caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4x2m' size='340' side='right'caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chatd Chatd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4X2M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X2M FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0065500 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [https://pdbe.org/4x2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [https://www.ebi.ac.uk/pdbsum/4x2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2m ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [~~http~~://pdbe.org/4x2m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4x2m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2m ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0SG92_CHATD G0SG92_CHATD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chatd~~]]	+	[[Category: Chaetomium thermophilum var. thermophilum DSM 1495]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aibara, S]]	+	[[Category: Aibara S]]
-	[[Category: Stewart, M]]	+	[[Category: Stewart M]]
-	[[Category: Valkov, E]]	+	[[Category: Valkov E]]
-	~~[[Category: Mrna nuclear export factor]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 08:22, 23 May 2019

OCA — Thu, 23 May 2019 08:22:27 GMT

←Older revision		Revision as of 08:22, 23 May 2019
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	==Structure of Mtr2==		==Structure of Mtr2==
-	<StructureSection load='4x2m' size='340' side='right' caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4x2m' size='340' side='right'caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chatd Chatd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2M FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [http://pdbe.org/4x2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [http://www.ebi.ac.uk/pdbsum/4x2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2m ProSAT]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CTHT_0065500 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=759272 CHATD])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [http://pdbe.org/4x2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [http://www.ebi.ac.uk/pdbsum/4x2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chatd]]
		+	[[Category: Large Structures]]
	[[Category: Aibara, S]]		[[Category: Aibara, S]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]

OCA at 13:28, 19 April 2017

OCA — Wed, 19 Apr 2017 13:28:32 GMT

←Older revision		Revision as of 13:28, 19 April 2017
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		+
	==Structure of Mtr2==		==Structure of Mtr2==
	<StructureSection load='4x2m' size='340' side='right' caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4x2m' size='340' side='right' caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2M FirstGlance]. <br>		<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2M FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [http://www.ebi.ac.uk/pdbsum/4x2m PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [http://pdbe.org/4x2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [http://www.ebi.ac.uk/pdbsum/4x2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4x2m" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:20, 15 July 2015

OCA — Wed, 15 Jul 2015 13:20:57 GMT

←Older revision		Revision as of 13:20, 15 July 2015
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-	'''~~Unreleased~~ structure'''	+	==Structure of Mtr2==
		+	<StructureSection load='4x2m' size='340' side='right' caption='[[4x2m]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4x2m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2M FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x2m RCSB], [http://www.ebi.ac.uk/pdbsum/4x2m PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Members of the Mex67-Mtr2/NXF-NXT1 family are the principal mediators of the nuclear export of mRNA. Mex67/NXF1 has a modular structure based on four domains (RRM, LRR, NTF2-like and UBA) that are thought to be present across species, although the level of sequence conservation between organisms, especially in lower eukaryotes, is low. Here, the crystal structures of these domains from the thermophilic fungus Chaetomium thermophilum are presented together with small-angle X-ray scattering (SAXS) and in vitro RNA-binding data that indicate that, not withstanding the limited sequence conservation between different NXF family members, the molecules retain similar structural and RNA-binding properties. Moreover, the resolution of crystal structures obtained with the C. thermophilum domains was often higher than that obtained previously and, when combined with solution and biochemical studies, provided insight into the structural organization, self-association and RNA-binding properties of Mex67-Mtr2 that facilitate mRNA nuclear export.

-	~~The entry 4x2m is ON HOLD until Paper Publication~~	+	Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.,Aibara S, Valkov E, Lamers MH, Dimitrova L, Hurt E, Stewart M Acta Crystallogr F Struct Biol Commun. 2015 Jul;71(Pt 7):876-88. doi:, 10.1107/S2053230X15008766. Epub 2015 Jun 27. PMID:26144233<ref>PMID:26144233</ref>

-	~~Authors: Aibara~~, S.~~, Valkov, E., Stewart, M~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Structure of Mtr2~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Aibara, S]]		[[Category: Aibara, S]]
		+	[[Category: Stewart, M]]
	[[Category: Valkov, E]]		[[Category: Valkov, E]]
-	[[Category: ~~Stewart, M~~]]	+	[[Category: Mrna nuclear export factor]]
		+	[[Category: Transport protein]]

OCA at 20:22, 24 December 2014

OCA — Wed, 24 Dec 2014 20:22:27 GMT

←Older revision		Revision as of 20:22, 24 December 2014
Line 6:		Line 6:

	Description: Structure of Mtr2		Description: Structure of Mtr2
		+	[[Category: Unreleased Structures]]
		+	[[Category: Aibara, S]]
		+	[[Category: Valkov, E]]
		+	[[Category: Stewart, M]]

OCA: Protected "4x2m" [edit=sysop:move=sysop]

OCA — Wed, 03 Dec 2014 08:47:08 GMT

Protected "4x2m" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:47, 3 December 2014

OCA: New page: '''Unreleased structure''' The entry 4x2m is ON HOLD until Paper Publication Authors: Aibara, S., Valkov, E., Stewart, M. Description: Structure of Mtr2

OCA — Wed, 03 Dec 2014 08:47:07 GMT

New page: '''Unreleased structure''' The entry 4x2m is ON HOLD until Paper Publication Authors: Aibara, S., Valkov, E., Stewart, M. Description: Structure of Mtr2

New page

'''Unreleased structure'''

The entry 4x2m is ON HOLD until Paper Publication

Authors: Aibara, S., Valkov, E., Stewart, M.

Description: Structure of Mtr2