4xen - Revision history

OCA at 15:27, 8 November 2023

OCA — Wed, 08 Nov 2023 15:27:24 GMT

←Older revision		Revision as of 15:27, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XEN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [https://pdbe.org/4xen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [https://www.ebi.ac.uk/pdbsum/4xen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xen ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [https://pdbe.org/4xen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [https://www.ebi.ac.uk/pdbsum/4xen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xen ProSAT]</span></td></tr>
	</table>		</table>

OCA at 21:25, 12 April 2023

OCA — Wed, 12 Apr 2023 21:25:34 GMT

←Older revision		Revision as of 21:25, 12 April 2023
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	<StructureSection load='4xen' size='340' side='right'caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4xen' size='340' side='right'caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4XEN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XEN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wld\|4wld]], [[4wlt\|4wlt]], [[4wlx\|4wlx]], [[4wly\|4wly]], [[4wm1\|4wm1]], [[4wm2\|4wm2]], [[4wm3\|4wm3]], [[4wm4\|4wm4]], [[4wm5\|4wm5]], [[4wm6\|4wm6]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [https://pdbe.org/4xen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [https://www.ebi.ac.uk/pdbsum/4xen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xen ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [~~http~~://pdbe.org/4xen PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4xen PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4xen ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>	+	[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Nagae T]]
-	[[Category: Nagae, T]]	+	[[Category: Watanabe N]]
-	[[Category: Watanabe, N]]	+	[[Category: Yamada H]]
-	[[Category: Yamada, H]]	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:34, 29 May 2019

OCA — Wed, 29 May 2019 07:34:29 GMT

←Older revision		Revision as of 07:34, 29 May 2019
Line 1:		Line 1:

	==High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa==		==High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa==
-	<StructureSection load='4xen' size='340' side='right' caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='4xen' size='340' side='right'caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEN FirstGlance]. <br>
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4xen" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4xen" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Nagae, T]]		[[Category: Nagae, T]]

OCA at 18:46, 1 February 2017

OCA — Wed, 01 Feb 2017 18:46:26 GMT

←Older revision		Revision as of 18:46, 1 February 2017
Line 1:		Line 1:
		+
	==High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa==		==High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa==
	<StructureSection load='4xen' size='340' side='right' caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4xen' size='340' side='right' caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wld\|4wld]], [[4wlt\|4wlt]], [[4wlx\|4wlx]], [[4wly\|4wly]], [[4wm1\|4wm1]], [[4wm2\|4wm2]], [[4wm3\|4wm3]], [[4wm4\|4wm4]], [[4wm5\|4wm5]], [[4wm6\|4wm6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wld\|4wld]], [[4wlt\|4wlt]], [[4wlx\|4wlx]], [[4wly\|4wly]], [[4wm1\|4wm1]], [[4wm2\|4wm2]], [[4wm3\|4wm3]], [[4wm4\|4wm4]], [[4wm5\|4wm5]], [[4wm6\|4wm6]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [http://www.ebi.ac.uk/pdbsum/4xen PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [http://pdbe.org/4xen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [http://www.ebi.ac.uk/pdbsum/4xen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xen ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4xen" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:02, 22 April 2015

OCA — Wed, 22 Apr 2015 07:02:23 GMT

←Older revision		Revision as of 07:02, 22 April 2015
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>		[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Crystal structures of hen egg-white lysozyme (HEWL) determined under pressures ranging from ambient pressure to 950 MPa are presented. From 0.1 to 710 MPa, the molecular and internal cavity volumes are monotonically compressed. However, from 710 to 890 MPa the internal cavity volume remains almost constant. Moreover, as the pressure increases to 950 MPa, the tetragonal crystal of HEWL undergoes a phase transition from P43212 to P43. Under high pressure, the crystal structure of the enzyme undergoes several local and global changes accompanied by changes in hydration structure. For example, water molecules penetrate into an internal cavity neighbouring the active site and induce an alternate conformation of one of the catalytic residues, Glu35. These phenomena have not been detected by conventional X-ray crystal structure analysis and might play an important role in the catalytic activity of HEWL.
		+
		+	High-pressure protein crystallography of hen egg-white lysozyme.,Yamada H, Nagae T, Watanabe N Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):742-53. doi:, 10.1107/S1399004715000292. Epub 2015 Mar 26. PMID:25849385<ref>PMID:25849385</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:18, 8 April 2015

OCA — Wed, 08 Apr 2015 11:18:34 GMT

←Older revision		Revision as of 11:18, 8 April 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa==
-		+	<StructureSection load='4xen' size='340' side='right' caption='[[4xen]], [[Resolution\|resolution]] 1.55Å' scene=''>
-	~~The entry~~ 4xen is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4xen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEN FirstGlance]. <br>
-	~~Authors~~: ~~Yamada~~, H., ~~Watanabe~~, N., ~~Nagae~~, T.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wld\|4wld]], [[4wlt\|4wlt]], [[4wlx\|4wlx]], [[4wly\|4wly]], [[4wm1\|4wm1]], [[4wm2\|4wm2]], [[4wm3\|4wm3]], [[4wm4\|4wm4]], [[4wm5\|4wm5]], [[4wm6\|4wm6]]</td></tr>
-	~~Description~~: ~~High pressure protein crystallography of hen egg white lysozyme~~ in ~~complex~~ with ~~Tetra~~-~~N-acetylchitotetraose at 920 MPa~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xen RCSB], [http://www.ebi.ac.uk/pdbsum/4xen PDBsum]</span></td></tr>
-	[[Category: ~~Watanabe, N~~]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Gallus gallus]]
		+	[[Category: Lysozyme]]
	[[Category: Nagae, T]]		[[Category: Nagae, T]]
		+	[[Category: Watanabe, N]]
	[[Category: Yamada, H]]		[[Category: Yamada, H]]
		+	[[Category: Hydrolase]]

OCA: Protected "4xen" [edit=sysop:move=sysop]

OCA — Wed, 31 Dec 2014 14:04:08 GMT

Protected "4xen" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:04, 31 December 2014

OCA: New page: '''Unreleased structure''' The entry 4xen is ON HOLD Authors: Yamada, H., Watanabe, N., Nagae, T. Description: High pressure protein crystallography of hen egg white lysozyme in comple...

OCA — Wed, 31 Dec 2014 14:04:06 GMT

New page: '''Unreleased structure''' The entry 4xen is ON HOLD Authors: Yamada, H., Watanabe, N., Nagae, T. Description: High pressure protein crystallography of hen egg white lysozyme in comple...

New page

'''Unreleased structure'''

The entry 4xen is ON HOLD

Authors: Yamada, H., Watanabe, N., Nagae, T.

Description: High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa
[[Category: Unreleased Structures]]
[[Category: Watanabe, N]]
[[Category: Nagae, T]]
[[Category: Yamada, H]]