4xjx - Revision history

OCA at 10:48, 10 January 2024

OCA — Wed, 10 Jan 2024 10:48:51 GMT

←Older revision		Revision as of 10:48, 10 January 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJX FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [https://pdbe.org/4xjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [https://www.ebi.ac.uk/pdbsum/4xjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [https://pdbe.org/4xjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [https://www.ebi.ac.uk/pdbsum/4xjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjx ProSAT]</span></td></tr>
	</table>		</table>

OCA at 17:40, 26 April 2023

OCA — Wed, 26 Apr 2023 17:40:46 GMT

←Older revision		Revision as of 17:40, 26 April 2023
Line 3:		Line 3:
	<StructureSection load='4xjx' size='340' side='right'caption='[[4xjx]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='4xjx' size='340' side='right'caption='[[4xjx]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4XJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be7\|4be7]], [[4beb\|4beb]], [[4bec\|4bec]], [[2w00\|2w00]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [https://pdbe.org/4xjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [https://www.ebi.ac.uk/pdbsum/4xjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjx ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hsdR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [~~http~~://pdbe.org/4xjx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4xjx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjx ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/T1R1_ECOLX T1R1_ECOLX] The restriction (R) subunit of a type I restriction enzyme that recognizes 5'-GAAN(7)RTCG-3' and cleaves a random distance away. Subunit R is required for both nuclease and ATPase activities, but not for modification (Probable) (PubMed:12654995). After locating an unmethylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (Probable). The enzyme undergoes major structural changes to bring the motor domains into contact with DNA, allowing DNA translocation. This prevents DNA access to the catalytic domains of both the R and M subunits, preventing both restriction and methylation (PubMed:32483229).<ref>PMID:32483229</ref> <ref>PMID:12654995</ref> <ref>PMID:2784505</ref> <ref>PMID:32483229</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baikova, T]]	+	[[Category: Baikova T]]
-	[[Category: Degtjarik, O]]	+	[[Category: Degtjarik O]]
-	[[Category: Ettrich, R]]	+	[[Category: Ettrich R]]
-	[[Category: Kuta-Smatanova, I]]	+	[[Category: Kuta-Smatanova I]]
-	[[Category: Moche, M]]	+	[[Category: Moche M]]
-	[[Category: Stsiapanava, A]]	+	[[Category: Stsiapanava A]]
-	~~[[Category: Atp]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Restriction enzyme~~]]	+

OCA at 07:27, 29 May 2019

OCA — Wed, 29 May 2019 07:27:45 GMT

←Older revision		Revision as of 07:27, 29 May 2019
Line 1:		Line 1:
		+
	==STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP==		==STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP==
-	<StructureSection load='4xjx' size='340' side='right' caption='[[4xjx]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='4xjx' size='340' side='right'caption='[[4xjx]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be7\|4be7]], [[4beb\|4beb]], [[4bec\|4bec]], [[2w00\|2w00]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be7\|4be7]], [[4beb\|4beb]], [[4bec\|4bec]], [[2w00\|2w00]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [http://pdbe.org/4xjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [http://www.ebi.ac.uk/pdbsum/4xjx PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hsdR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [http://pdbe.org/4xjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [http://www.ebi.ac.uk/pdbsum/4xjx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjx ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Baikova, T]]		[[Category: Baikova, T]]
	[[Category: Degtjarik, O]]		[[Category: Degtjarik, O]]

OCA at 17:13, 20 January 2016

OCA — Wed, 20 Jan 2016 17:13:42 GMT

←Older revision		Revision as of 17:13, 20 January 2016
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP==
-		+	<StructureSection load='4xjx' size='340' side='right' caption='[[4xjx]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~The entry~~ 4xjx is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4xjx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJX FirstGlance]. <br>
-	~~Authors~~: ~~Baikova, T~~.~~, Stsiapanava, A~~.~~, Moche, M~~.~~, Degtjarik, O~~.~~, Kuta~~-~~Smatanova, I~~.~~, Ettrich, R~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4be7\|4be7]], [[4beb\|4beb]], [[4bec\|4bec]], [[2w00\|2w00]]</td></tr>
-	~~Description~~: ~~STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH~~ ATP	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjx OCA], [http://pdbe.org/4xjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjx RCSB], [http://www.ebi.ac.uk/pdbsum/4xjx PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Kuta~~-~~Smatanova~~, I]]	+	__TOC__
-	[[Category: ~~Ettrich~~, R]]	+	</StructureSection>
		+	[[Category: Baikova, T]]
	[[Category: Degtjarik, O]]		[[Category: Degtjarik, O]]
		+	[[Category: Ettrich, R]]
		+	[[Category: Kuta-Smatanova, I]]
	[[Category: Moche, M]]		[[Category: Moche, M]]
-	[[Category: Baikova, T]]
	[[Category: Stsiapanava, A]]		[[Category: Stsiapanava, A]]
		+	[[Category: Atp]]
		+	[[Category: Hydrolase]]
		+	[[Category: Restriction enzyme]]

OCA at 23:12, 30 November 2015

OCA — Mon, 30 Nov 2015 23:12:38 GMT

←Older revision		Revision as of 23:12, 30 November 2015
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	Description: STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP		Description: STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Baikova, T]]
-	[[Category: Stsiapanava, A]]
	[[Category: Kuta-Smatanova, I]]		[[Category: Kuta-Smatanova, I]]
	[[Category: Ettrich, R]]		[[Category: Ettrich, R]]
	[[Category: Degtjarik, O]]		[[Category: Degtjarik, O]]
	[[Category: Moche, M]]		[[Category: Moche, M]]
		+	[[Category: Baikova, T]]
		+	[[Category: Stsiapanava, A]]

OCA at 09:52, 18 March 2015

OCA — Wed, 18 Mar 2015 09:52:24 GMT

←Older revision		Revision as of 09:52, 18 March 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4xjx is ON HOLD	+	The entry 4xjx is ON HOLD until Paper Publication

	Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., Ettrich, R.		Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., Ettrich, R.

OCA at 11:25, 18 February 2015

OCA — Wed, 18 Feb 2015 11:25:01 GMT

←Older revision		Revision as of 11:25, 18 February 2015
Line 3:		Line 3:
	The entry 4xjx is ON HOLD		The entry 4xjx is ON HOLD

-	Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., ~~Rudiger~~, J.	+	Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., Ettrich, R.

	Description: STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP		Description: STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP
Line 10:		Line 10:
	[[Category: Stsiapanava, A]]		[[Category: Stsiapanava, A]]
	[[Category: Kuta-Smatanova, I]]		[[Category: Kuta-Smatanova, I]]
		+	[[Category: Ettrich, R]]
	[[Category: Degtjarik, O]]		[[Category: Degtjarik, O]]
	[[Category: Moche, M]]		[[Category: Moche, M]]
-	[[Category: Rudiger, J]]

OCA: Protected "4xjx" [edit=sysop:move=sysop]

OCA — Wed, 21 Jan 2015 15:56:07 GMT

Protected "4xjx" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:56, 21 January 2015

OCA: New page: '''Unreleased structure''' The entry 4xjx is ON HOLD Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., Rudiger, J. Description: STRUCTURE OF MUTANT (...

OCA — Wed, 21 Jan 2015 15:56:06 GMT

New page: '''Unreleased structure''' The entry 4xjx is ON HOLD Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., Rudiger, J. Description: STRUCTURE OF MUTANT (...

New page

'''Unreleased structure'''

The entry 4xjx is ON HOLD

Authors: Baikova, T., Stsiapanava, A., Moche, M., Degtjarik, O., Kuta-Smatanova, I., Rudiger, J.

Description: STRUCTURE OF MUTANT (E165H) OF THE HSDR SUBUNIT OF THE ECOR124I RESTRICTION ENZYME IN COMPLEX WITH ATP
[[Category: Unreleased Structures]]
[[Category: Baikova, T]]
[[Category: Stsiapanava, A]]
[[Category: Kuta-Smatanova, I]]
[[Category: Degtjarik, O]]
[[Category: Moche, M]]
[[Category: Rudiger, J]]