4xo2 - Revision history

OCA at 09:02, 20 March 2024

OCA — Wed, 20 Mar 2024 09:02:37 GMT

←Older revision		Revision as of 09:02, 20 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [https://pdbe.org/4xo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.952Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [https://pdbe.org/4xo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>		[https://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Escherichia Coli GnsA is a regulator of phosphatidylethanolamine synthesis and functions as a suppressor of both a secG null mutation and fabA6 mutations. GnsA may also be a toxin with the cognate antitoxin YmcE. Here we report the crystal structure of GnsA to 1.8 A. GnsA forms a V shaped hairpin structure that is tightly associated into a homodimer. Our comprehensive structural study suggests that GnsA is structurally similar to an outer membrane protein, suggesting a function of protein binding.
-
-	Crystal structure of GnsA from Escherichia coli.,Wei Y, Zhan L, Gao Z, Prive GG, Dong Y Biochem Biophys Res Commun. 2015 Jun 19;462(1):1-7. doi:, 10.1016/j.bbrc.2015.03.133. Epub 2015 Apr 1. PMID:25839658<ref>PMID:25839658</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4xo2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:45, 26 April 2023

OCA — Wed, 26 Apr 2023 17:45:07 GMT

←Older revision		Revision as of 17:45, 26 April 2023
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	<StructureSection load='4xo2' size='340' side='right'caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4xo2' size='340' side='right'caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xo1\|4xo1]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [https://pdbe.org/4xo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gnsA, yccL, b4517, JW0976 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [~~http~~://pdbe.org/4xo2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI]] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>	+	[https://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dong~~, Y H~~]]	+	[[Category: Dong YH]]
-	[[Category: Gao~~, Z Q~~]]	+	[[Category: Gao ZQ]]
-	[[Category: Wei, Y]]	+	[[Category: Wei Y]]
-	[[Category: Zhan~~, L H]]~~	+	[[Category: Zhan LH]]
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Suppressor~~]]	+

OCA at 07:09, 29 May 2019

OCA — Wed, 29 May 2019 07:09:28 GMT

←Older revision		Revision as of 07:09, 29 May 2019
Line 1:		Line 1:

	==crystal structure of GnsA from E.coli==		==crystal structure of GnsA from E.coli==
-	<StructureSection load='4xo2' size='340' side='right' caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='4xo2' size='340' side='right'caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xo1\|4xo1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xo1\|4xo1]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gnsA, yccL, b4517, JW0976 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [http://pdbe.org/4xo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [http://pdbe.org/4xo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Dong, Y H]]		[[Category: Dong, Y H]]
	[[Category: Gao, Z Q]]		[[Category: Gao, Z Q]]
	[[Category: Wei, Y]]		[[Category: Wei, Y]]
	[[Category: Zhan, L H]]		[[Category: Zhan, L H]]
		+	[[Category: Protein binding]]
	[[Category: Suppressor]]		[[Category: Suppressor]]

OCA at 17:05, 22 March 2017

OCA — Wed, 22 Mar 2017 17:05:28 GMT

←Older revision		Revision as of 17:05, 22 March 2017
Line 1:		Line 1:
		+
	==crystal structure of GnsA from E.coli==		==crystal structure of GnsA from E.coli==
	<StructureSection load='4xo2' size='340' side='right' caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='4xo2' size='340' side='right' caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xo1\|4xo1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xo1\|4xo1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [http://pdbe.org/4xo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4xo2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:03, 17 June 2015

OCA — Wed, 17 Jun 2015 15:03:13 GMT

←Older revision		Revision as of 15:03, 17 June 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==crystal structure of GnsA from E.coli==
		+	<StructureSection load='4xo2' size='340' side='right' caption='[[4xo2]], [[Resolution\|resolution]] 1.95Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xo1\|4xo1]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo2 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI]] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Escherichia Coli GnsA is a regulator of phosphatidylethanolamine synthesis and functions as a suppressor of both a secG null mutation and fabA6 mutations. GnsA may also be a toxin with the cognate antitoxin YmcE. Here we report the crystal structure of GnsA to 1.8 A. GnsA forms a V shaped hairpin structure that is tightly associated into a homodimer. Our comprehensive structural study suggests that GnsA is structurally similar to an outer membrane protein, suggesting a function of protein binding.

-	~~The entry 4xo2 is ON HOLD until Paper Publication~~	+	Crystal structure of GnsA from Escherichia coli.,Wei Y, Zhan L, Gao Z, Prive GG, Dong Y Biochem Biophys Res Commun. 2015 Jun 19;462(1):1-7. doi:, 10.1016/j.bbrc.2015.03.133. Epub 2015 Apr 1. PMID:25839658<ref>PMID:25839658</ref>

-	~~Authors: Zhan~~, L.H.~~, Gao, Z.Q., Wei, Y., Dong, Y.H~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: crystal structure of GnsA from E.coli~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: Gao, Z.Q]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Dong, Y H]]
		+	[[Category: Gao, Z Q]]
	[[Category: Wei, Y]]		[[Category: Wei, Y]]
-	[[Category: Zhan, L.H]]	+	[[Category: Zhan, L H]]
-	[[Category: ~~Dong, Y.H~~]]	+	[[Category: Suppressor]]

OCA at 14:39, 7 February 2015

OCA — Sat, 07 Feb 2015 14:39:02 GMT

←Older revision		Revision as of 14:39, 7 February 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4xo2 is ON HOLD	+	The entry 4xo2 is ON HOLD until Paper Publication

	Authors: Zhan, L.H., Gao, Z.Q., Wei, Y., Dong, Y.H.		Authors: Zhan, L.H., Gao, Z.Q., Wei, Y., Dong, Y.H.

OCA: Protected "4xo2" [edit=sysop:move=sysop]

OCA — Wed, 21 Jan 2015 16:05:15 GMT

Protected "4xo2" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:05, 21 January 2015

OCA: New page: '''Unreleased structure''' The entry 4xo2 is ON HOLD Authors: Zhan, L.H., Gao, Z.Q., Wei, Y., Dong, Y.H. Description: crystal structure of GnsA from E.coli [[Category: Unreleased Struc...

OCA — Wed, 21 Jan 2015 16:05:13 GMT

New page: '''Unreleased structure''' The entry 4xo2 is ON HOLD Authors: Zhan, L.H., Gao, Z.Q., Wei, Y., Dong, Y.H. Description: crystal structure of GnsA from E.coli [[Category: Unreleased Struc...

New page

'''Unreleased structure'''

The entry 4xo2 is ON HOLD

Authors: Zhan, L.H., Gao, Z.Q., Wei, Y., Dong, Y.H.

Description: crystal structure of GnsA from E.coli
[[Category: Unreleased Structures]]
[[Category: Gao, Z.Q]]
[[Category: Wei, Y]]
[[Category: Zhan, L.H]]
[[Category: Dong, Y.H]]