4y4q - Revision history

OCA at 10:52, 10 January 2024

OCA — Wed, 10 Jan 2024 10:52:44 GMT

←Older revision		Revision as of 10:52, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_PCS8235 Streptococcus pneumoniae PCS8235]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_PCS8235 Streptococcus pneumoniae PCS8235]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [https://pdbe.org/4y4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [https://www.ebi.ac.uk/pdbsum/4y4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4q ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.162Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [https://pdbe.org/4y4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [https://www.ebi.ac.uk/pdbsum/4y4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4q ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 18:06, 26 April 2023

OCA — Wed, 26 Apr 2023 18:06:27 GMT

←Older revision		Revision as of 18:06, 26 April 2023
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	==Crystal structure of sortase B from Type II pilus of Streptococcus pneumoniae==		==Crystal structure of sortase B from Type II pilus of Streptococcus pneumoniae==
-	<StructureSection load='4y4q' size='340' side='right' caption='[[4y4q]], [[Resolution\|resolution]] 2.16Å' scene=''>	+	<StructureSection load='4y4q' size='340' side='right'caption='[[4y4q]], [[Resolution\|resolution]] 2.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae_pcs8235~~ Streptococcus pneumoniae ~~pcs8235~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_PCS8235 Streptococcus pneumoniae PCS8235]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PCS8235_00725 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1159083 Streptococcus pneumoniae PCS8235])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [https://pdbe.org/4y4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [https://www.ebi.ac.uk/pdbsum/4y4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4q ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [~~http~~://pdbe.org/4y4q PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4y4q PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4q ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0M3KL14_STREE A0A0M3KL14_STREE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptococcus pneumoniae pcs8235~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Dessen, A~~]]	+	[[Category: Streptococcus pneumoniae PCS8235]]
-	[[Category: ~~Guilmi,~~ A ~~M.Di~~]]	+	[[Category: Dessen A]]
-	[[Category: ~~Shaik, M M~~]]	+	[[Category: Di Guilmi AM]]
-	[[Category: ~~Hydrolase]]~~	+	[[Category: Shaik MM]]
-	~~[[Category: Pilus]]~~	+
-	~~[[Category: Sortase]]~~	+
-	~~[[Category: Type ii pilus]]~~	+
-	~~[[Category: Virulence factor~~]]	+

OCA at 16:19, 16 November 2017

OCA — Thu, 16 Nov 2017 16:19:29 GMT

←Older revision		Revision as of 16:19, 16 November 2017
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		+
	==Crystal structure of sortase B from Type II pilus of Streptococcus pneumoniae==		==Crystal structure of sortase B from Type II pilus of Streptococcus pneumoniae==
	<StructureSection load='4y4q' size='340' side='right' caption='[[4y4q]], [[Resolution\|resolution]] 2.16Å' scene=''>		<StructureSection load='4y4q' size='340' side='right' caption='[[4y4q]], [[Resolution\|resolution]] 2.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_pcs8235 Streptococcus pneumoniae pcs8235]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://pdbe.org/4y4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PCS8235_00725 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1159083 Streptococcus pneumoniae PCS8235])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://pdbe.org/4y4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4q ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Streptococcus pneumoniae pcs8235]]
	[[Category: Dessen, A]]		[[Category: Dessen, A]]
	[[Category: Guilmi, A M.Di]]		[[Category: Guilmi, A M.Di]]

OCA at 07:11, 30 September 2015

OCA — Wed, 30 Sep 2015 07:11:24 GMT

←Older revision		Revision as of 07:11, 30 September 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://pdbe.org/4y4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 13:		Line 13:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4y4q" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:55, 5 August 2015

OCA — Wed, 05 Aug 2015 13:55:35 GMT

←Older revision		Revision as of 13:55, 5 August 2015
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pili are fibrous appendages expressed on the surface of a vast number of bacterial species, and their role in surface adhesion is important for processes such as infection, colonization, and biofilm formation. The human pathogen Streptococcus pneumoniae expresses two different types of pili, PI-1 and PI-2, both of which require the concerted action of structural proteins and sortases for their polymerization. The type PI-1 streptococcal pilus is a complex, well-studied structure, but the PI-2 type, present in a number of invasive pneumococcal serotypes, has to date remained less well understood. The PI-2 pilus consists of repeated units of a single protein, PitB, whose covalent association is catalyzed by cognate sortase SrtG-1 and partner protein SipA. Here we report the high-resolution crystal structures of PitB and SrtG1 and use molecular modeling to visualize a 'trapped' 1:1 complex between the two molecules. X-ray crystallography and electron microscopy reveal that the pneumococcal PI-2 backbone fiber is formed by PitB monomers associated in 'head-to-tail' fashion, and that short, flexible fibers can be formed even in the absence of coadjuvant proteins. These observations, obtained with a simple pilus biosynthetic system, are likely to be applicable to other fiber formation processes in a variety of Gram-positive organisms.
		+
		+	A structural snapshot of type II pilus formation in Streptococcus pneumoniae.,Shaik MM, Lombardi C, Maragno Trindade D, Fenel D, Schoehn G, Di Guilmi AM, Dessen A J Biol Chem. 2015 Jul 21. pii: jbc.M115.647834. PMID:26198632<ref>PMID:26198632</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:51, 29 July 2015

OCA — Wed, 29 Jul 2015 14:51:15 GMT

←Older revision		Revision as of 14:51, 29 July 2015
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-	'''~~Unreleased structure~~'''	+	==Crystal structure of sortase B from Type II pilus of Streptococcus pneumoniae==
-		+	<StructureSection load='4y4q' size='340' side='right' caption='[[4y4q]], [[Resolution\|resolution]] 2.16Å' scene=''>
-	~~The entry~~ 4y4q is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4y4q]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y4Q FirstGlance]. <br>
-	~~Authors~~: ~~Shaik, M~~.M.~~, Dessen, A~~.~~, Di Guilmi, A~~.M.	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y4q RCSB], [http://www.ebi.ac.uk/pdbsum/4y4q PDBsum]</span></td></tr>
-		+	</table>
-	~~Description~~:	+	__TOC__
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</StructureSection>
	[[Category: Dessen, A]]		[[Category: Dessen, A]]
-	[[Category: Di Guilmi, A.M]]	+	[[Category: Guilmi, A M.Di]]
-	[[Category: Shaik, M.M]]	+	[[Category: Shaik, M M]]
		+	[[Category: Hydrolase]]
		+	[[Category: Pilus]]
		+	[[Category: Sortase]]
		+	[[Category: Type ii pilus]]
		+	[[Category: Virulence factor]]

OCA at 12:40, 25 February 2015

OCA — Wed, 25 Feb 2015 12:40:32 GMT

←Older revision		Revision as of 12:40, 25 February 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4y4q is ON HOLD	+	The entry 4y4q is ON HOLD until Paper Publication

	Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M.		Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M.

OCA: Protected "4y4q" [edit=sysop:move=sysop]

OCA — Wed, 18 Feb 2015 12:01:42 GMT

Protected "4y4q" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:01, 18 February 2015

OCA: New page: '''Unreleased structure''' The entry 4y4q is ON HOLD Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M. Description: Category: Unreleased Structures Category: Dessen, A [[Categ...

OCA — Wed, 18 Feb 2015 12:01:40 GMT

New page: '''Unreleased structure''' The entry 4y4q is ON HOLD Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M. Description: Category: Unreleased Structures Category: Dessen, A [[Categ...

New page

'''Unreleased structure'''

The entry 4y4q is ON HOLD

Authors: Shaik, M.M., Dessen, A., Di Guilmi, A.M.

Description:
[[Category: Unreleased Structures]]
[[Category: Dessen, A]]
[[Category: Di Guilmi, A.M]]
[[Category: Shaik, M.M]]