4y5q - Revision history

OCA at 13:02, 1 March 2024

OCA — Fri, 01 Mar 2024 13:02:43 GMT

←Older revision		Revision as of 13:02, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [https://pdbe.org/4y5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [https://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [https://pdbe.org/4y5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [https://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:59, 3 May 2023

OCA — Wed, 03 May 2023 07:59:38 GMT

←Older revision		Revision as of 07:59, 3 May 2023
Line 3:		Line 3:
	<StructureSection load='4y5q' size='340' side='right'caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4y5q' size='340' side='right'caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Crypi Crypi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ncg\|3ncg]], [[3mwu\|3mwu]], [[3igo\|3igo]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [https://pdbe.org/4y5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [https://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cgd3_920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [~~http~~://pdbe.org/4y5q PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/A3FQ16_CRYPI A3FQ16_CRYPI]
-	Diseases caused by the apicomplexan protozoans Toxoplasma gondii and Cryptosporidium parvum are a major health concern. The life cycle of these parasites is regulated by a family of calcium-dependent protein kinases (CDPKs) that have no direct homologs in the human host. Fortuitously, CDPK1 from both parasites contains a rare glycine gatekeeper residue adjacent to the ATP-binding pocket. This has allowed creation of a series of C3-substituted pyrazolopyrimidine compounds that are potent inhibitors selective for CDPK1 over a panel of human kinases. Here we demonstrate that selectivity is further enhanced by modi fi cation of the scaffold at the C1 position. The explanation for this unexpected result is provided by crystal structures of the inhibitors bound to CDPK1 and the human kinase c-SRC. Furthermore, the insight gained from these studies was applied to transform an alternative ATP-competitive scaffold lacking potency and selectivity for CDPK1 into a low nanomolar inhibitor of this enzyme with no activity against SRC.	+
-		+
-	Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.,Larson ET, Ojo KK, Murphy RC, Johnson SM, Zhang Z, Kim JE, Leibly DJ, Fox AM, Reid MC, Dale EJ, Perera BG, Kim J, Hewitt SN, Hol WG, Verlinde CL, Fan E, Van Voorhis WC, Maly DJ, Merritt EA J Med Chem. 2012 Feb 27. PMID:~~22369268<ref>PMID:22369268<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 4y5q" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Crypi~~]]	+	[[Category: Cryptosporidium parvum Iowa II]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Larson~~, E T]]~~	+	[[Category: Larson ET]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Merritt EA]]
-	[[Category: Merritt~~, E A]]~~	+
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Bumped kinase inhibitor]]~~	+
-	~~[[Category: Calcium-binding]]~~	+
-	~~[[Category: Calmodulin]]~~	+
-	~~[[Category: Msgpp]]~~	+
-	~~[[Category: Serine/threonine protein kinase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 15:51, 11 December 2019

OCA — Wed, 11 Dec 2019 15:51:43 GMT

←Older revision		Revision as of 15:51, 11 December 2019
Line 1:		Line 1:

	==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP==		==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP==
-	<StructureSection load='4y5q' size='340' side='right' caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4y5q' size='340' side='right'caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Crypi]]		[[Category: Crypi]]
		+	[[Category: Large Structures]]
	[[Category: Larson, E T]]		[[Category: Larson, E T]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 15:39, 15 November 2017

OCA — Wed, 15 Nov 2017 15:39:46 GMT

←Older revision		Revision as of 15:39, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4y5q' size='340' side='right' caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4y5q' size='340' side='right' caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ncg\|3ncg]], [[3mwu\|3mwu]], [[3igo\|3igo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ncg\|3ncg]], [[3mwu\|3mwu]], [[3igo\|3igo]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cgd3_920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [http://pdbe.org/4y5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [http://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [http://pdbe.org/4y5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [http://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Crypi]]
	[[Category: Larson, E T]]		[[Category: Larson, E T]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 01:49, 10 March 2017

OCA — Fri, 10 Mar 2017 01:49:45 GMT

←Older revision		Revision as of 01:49, 10 March 2017
Line 1:		Line 1:
		+
	==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP==		==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP==
	<StructureSection load='4y5q' size='340' side='right' caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4y5q' size='340' side='right' caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ncg\|3ncg]], [[3mwu\|3mwu]], [[3igo\|3igo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ncg\|3ncg]], [[3mwu\|3mwu]], [[3igo\|3igo]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [http://www.ebi.ac.uk/pdbsum/4y5q PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [http://pdbe.org/4y5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [http://www.ebi.ac.uk/pdbsum/4y5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y5q ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4y5q" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:51, 25 February 2015

OCA — Wed, 25 Feb 2015 13:51:27 GMT

←Older revision		Revision as of 13:51, 25 February 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP==
		+	<StructureSection load='4y5q' size='340' side='right' caption='[[4y5q]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4y5q]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y5Q FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ncg\|3ncg]], [[3mwu\|3mwu]], [[3igo\|3igo]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y5q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y5q RCSB], [http://www.ebi.ac.uk/pdbsum/4y5q PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Diseases caused by the apicomplexan protozoans Toxoplasma gondii and Cryptosporidium parvum are a major health concern. The life cycle of these parasites is regulated by a family of calcium-dependent protein kinases (CDPKs) that have no direct homologs in the human host. Fortuitously, CDPK1 from both parasites contains a rare glycine gatekeeper residue adjacent to the ATP-binding pocket. This has allowed creation of a series of C3-substituted pyrazolopyrimidine compounds that are potent inhibitors selective for CDPK1 over a panel of human kinases. Here we demonstrate that selectivity is further enhanced by modi fi cation of the scaffold at the C1 position. The explanation for this unexpected result is provided by crystal structures of the inhibitors bound to CDPK1 and the human kinase c-SRC. Furthermore, the insight gained from these studies was applied to transform an alternative ATP-competitive scaffold lacking potency and selectivity for CDPK1 into a low nanomolar inhibitor of this enzyme with no activity against SRC.

-	~~The entry 4y5q is ON HOLD~~	+	Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.,Larson ET, Ojo KK, Murphy RC, Johnson SM, Zhang Z, Kim JE, Leibly DJ, Fox AM, Reid MC, Dale EJ, Perera BG, Kim J, Hewitt SN, Hol WG, Verlinde CL, Fan E, Van Voorhis WC, Maly DJ, Merritt EA J Med Chem. 2012 Feb 27. PMID:22369268<ref>PMID:22369268</ref>

-	~~Authors: Merritt~~, E.A., Larson, E.T~~., Medical~~ Structural ~~Genomics of Pathogenic Protozoa (MSGPP)~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Activated Calcium~~-~~Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: ~~Larson, E.T~~]]	+	__TOC__
-	[[Category: ~~Medical Structural Genomics Of Pathogenic Protozoa (~~Msgpp)]]	+	</StructureSection>
-	[[Category: ~~Merritt, E.A~~]]	+	[[Category: Larson, E T]]
		+	[[Category: Structural genomic]]
		+	[[Category: Merritt, E A]]
		+	[[Category: Atp-binding]]
		+	[[Category: Bumped kinase inhibitor]]
		+	[[Category: Calcium-binding]]
		+	[[Category: Calmodulin]]
		+	[[Category: Msgpp]]
		+	[[Category: Serine/threonine protein kinase]]
		+	[[Category: Transferase]]

OCA: Protected "4y5q" [edit=sysop:move=sysop]

OCA — Wed, 18 Feb 2015 12:03:37 GMT

Protected "4y5q" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:03, 18 February 2015

OCA: New page: '''Unreleased structure''' The entry 4y5q is ON HOLD Authors: Merritt, E.A., Larson, E.T., Medical Structural Genomics of Pathogenic Protozoa (MSGPP) Description: Activated Calcium-Dep...

OCA — Wed, 18 Feb 2015 12:03:36 GMT

New page: '''Unreleased structure''' The entry 4y5q is ON HOLD Authors: Merritt, E.A., Larson, E.T., Medical Structural Genomics of Pathogenic Protozoa (MSGPP) Description: Activated Calcium-Dep...

New page

'''Unreleased structure'''

The entry 4y5q is ON HOLD

Authors: Merritt, E.A., Larson, E.T., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)

Description: Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP
[[Category: Unreleased Structures]]
[[Category: Larson, E.T]]
[[Category: Medical Structural Genomics Of Pathogenic Protozoa (Msgpp)]]
[[Category: Merritt, E.A]]