4ydz - Revision history

OCA at 11:31, 9 May 2024

OCA — Thu, 09 May 2024 11:31:26 GMT

←Older revision		Revision as of 11:31, 9 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [https://pdbe.org/4ydz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [https://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.6Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [https://pdbe.org/4ydz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [https://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:10, 3 May 2023

OCA — Wed, 03 May 2023 08:10:28 GMT

←Older revision		Revision as of 08:10, 3 May 2023
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	<StructureSection load='4ydz' size='340' side='right'caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>		<StructureSection load='4ydz' size='340' side='right'caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Caeel Caeel~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w1z\|3w1z]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [https://pdbe.org/4ydz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [https://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sip-1, F43D9.4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [~~http~~://pdbe.org/4ydz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SIP1_CAEEL SIP1_CAEEL]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caeel~~]]	+	[[Category: Caenorhabditis elegans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Buchner, J]]	+	[[Category: Buchner J]]
-	[[Category: Daake, M]]	+	[[Category: Daake M]]
-	[[Category: Fleckenstein, T]]	+	[[Category: Fleckenstein T]]
-	[[Category: Groll, M]]	+	[[Category: Groll M]]
-	[[Category: Haslbeck, M]]	+	[[Category: Haslbeck M]]
-	[[Category: Kastenmueller, A]]	+	[[Category: Kastenmueller A]]
-	[[Category: Krause, M]]	+	[[Category: Krause M]]
-	[[Category: Peters, C]]	+	[[Category: Peters C]]
-	[[Category: Stein~~, M L~~]]	+	[[Category: Stein ML]]
-	[[Category: Weinfurtner, D]]	+	[[Category: Weinfurtner D]]
-	[[Category: Weinkauf, S]]	+	[[Category: Weinkauf S]]
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Heat shock]]~~	+
-	~~[[Category: Molecular chaperone]]~~	+
-	~~[[Category: Protein aggregation]]~~	+
-	~~[[Category: Shsp~~]]	+

OCA at 07:09, 12 June 2019

OCA — Wed, 12 Jun 2019 07:09:58 GMT

←Older revision		Revision as of 07:09, 12 June 2019
Line 1:		Line 1:

	==Stress-induced protein 1 from Caenorhabditis elegans==		==Stress-induced protein 1 from Caenorhabditis elegans==
-	<StructureSection load='4ydz' size='340' side='right' caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>	+	<StructureSection load='4ydz' size='340' side='right'caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w1z\|3w1z]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w1z\|3w1z]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sip-1, F43D9.4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [http://pdbe.org/4ydz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [http://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [http://pdbe.org/4ydz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [http://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Caeel]]
		+	[[Category: Large Structures]]
	[[Category: Buchner, J]]		[[Category: Buchner, J]]
	[[Category: Daake, M]]		[[Category: Daake, M]]

OCA at 12:08, 12 April 2017

OCA — Wed, 12 Apr 2017 12:08:09 GMT

←Older revision		Revision as of 12:08, 12 April 2017
Line 1:		Line 1:
		+
	==Stress-induced protein 1 from Caenorhabditis elegans==		==Stress-induced protein 1 from Caenorhabditis elegans==
	<StructureSection load='4ydz' size='340' side='right' caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>		<StructureSection load='4ydz' size='340' side='right' caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w1z\|3w1z]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w1z\|3w1z]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [http://www.ebi.ac.uk/pdbsum/4ydz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [http://pdbe.org/4ydz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [http://www.ebi.ac.uk/pdbsum/4ydz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4ydz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:03, 10 June 2015

OCA — Wed, 10 Jun 2015 14:03:08 GMT

←Older revision		Revision as of 14:03, 10 June 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Stress-induced protein 1 from Caenorhabditis elegans==
		+	<StructureSection load='4ydz' size='340' side='right' caption='[[4ydz]], [[Resolution\|resolution]] 3.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ydz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDZ FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w1z\|3w1z]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ydz RCSB], [http://www.ebi.ac.uk/pdbsum/4ydz PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Small heat shock proteins (sHsps) are ubiquitous molecular chaperones that prevent the aggregation of unfolding proteins during proteotoxic stress. In Caenorhabditis elegans, Sip1 is the only sHsp exclusively expressed in oocytes and embryos. Here, we demonstrate that Sip1 is essential for heat shock survival of reproducing adults and embryos. X-ray crystallography and electron microscopy revealed that Sip1 exists in a range of well-defined globular assemblies consisting of two half-spheres, each made of dimeric "spokes." Strikingly, the oligomeric distribution of Sip1 as well as its chaperone activity depend on pH, with a trend toward smaller species and higher activity at acidic conditions such as present in nematode eggs. The analysis of the interactome shows that Sip1 has a specific substrate spectrum including proteins that are essential for embryo development.

-	The ~~entry 4ydz is ON HOLD~~	+	The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.,Fleckenstein T, Kastenmuller A, Stein ML, Peters C, Daake M, Krause M, Weinfurtner D, Haslbeck M, Weinkauf S, Groll M, Buchner J Mol Cell. 2015 May 22. pii: S1097-2765(15)00301-9. doi:, 10.1016/j.molcel.2015.04.019. PMID:26009280<ref>PMID:26009280</ref>

-	~~Authors: Fleckenstein~~, T.~~, Kastenmueller, A., Stein, M.L., Peters, C., Daake, M., Krause, M., Weinfurtner, D., Haslbeck, M., Weinkauf,~~ S.~~, Groll, M., Buchner, J~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Stress-induced protein 1 from Caenorhabditis elegans~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
-	~~[[Category: Kastenmueller, A]]~~	+	__TOC__
-	~~[[Category: Weinfurtner, D]]~~	+	</StructureSection>
-	~~[[Category: Krause, M]]~~	+
	[[Category: Buchner, J]]		[[Category: Buchner, J]]
-	[[Category: Stein, M.L]]
	[[Category: Daake, M]]		[[Category: Daake, M]]
		+	[[Category: Fleckenstein, T]]
		+	[[Category: Groll, M]]
	[[Category: Haslbeck, M]]		[[Category: Haslbeck, M]]
		+	[[Category: Kastenmueller, A]]
		+	[[Category: Krause, M]]
		+	[[Category: Peters, C]]
		+	[[Category: Stein, M L]]
		+	[[Category: Weinfurtner, D]]
	[[Category: Weinkauf, S]]		[[Category: Weinkauf, S]]
-	[[Category: ~~Groll, M~~]]	+	[[Category: Chaperone]]
-	[[Category: ~~Peters, C~~]]	+	[[Category: Heat shock]]
-	[[Category: ~~Fleckenstein, T~~]]	+	[[Category: Molecular chaperone]]
		+	[[Category: Protein aggregation]]
		+	[[Category: Shsp]]

OCA: Protected "4ydz" [edit=sysop:move=sysop]

OCA — Wed, 04 Mar 2015 10:21:10 GMT

Protected "4ydz" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:21, 4 March 2015

OCA: New page: '''Unreleased structure''' The entry 4ydz is ON HOLD Authors: Fleckenstein, T., Kastenmueller, A., Stein, M.L., Peters, C., Daake, M., Krause, M., Weinfurtner, D., Haslbeck, M., Weinkau...

OCA — Wed, 04 Mar 2015 10:21:08 GMT

New page: '''Unreleased structure''' The entry 4ydz is ON HOLD Authors: Fleckenstein, T., Kastenmueller, A., Stein, M.L., Peters, C., Daake, M., Krause, M., Weinfurtner, D., Haslbeck, M., Weinkau...

New page

'''Unreleased structure'''

The entry 4ydz is ON HOLD

Authors: Fleckenstein, T., Kastenmueller, A., Stein, M.L., Peters, C., Daake, M., Krause, M., Weinfurtner, D., Haslbeck, M., Weinkauf, S., Groll, M., Buchner, J.

Description: Stress-induced protein 1 from Caenorhabditis elegans
[[Category: Unreleased Structures]]
[[Category: Kastenmueller, A]]
[[Category: Weinfurtner, D]]
[[Category: Krause, M]]
[[Category: Buchner, J]]
[[Category: Stein, M.L]]
[[Category: Daake, M]]
[[Category: Haslbeck, M]]
[[Category: Weinkauf, S]]
[[Category: Groll, M]]
[[Category: Peters, C]]
[[Category: Fleckenstein, T]]