4ykq - Revision history

OCA at 13:03, 1 March 2024

OCA — Fri, 01 Mar 2024 13:03:39 GMT

←Older revision		Revision as of 13:03, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.91Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [https://pdbe.org/4ykq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [https://www.ebi.ac.uk/pdbsum/4ykq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [https://pdbe.org/4ykq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [https://www.ebi.ac.uk/pdbsum/4ykq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykq ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:17, 3 May 2023

OCA — Wed, 03 May 2023 08:17:13 GMT

←Older revision		Revision as of 08:17, 3 May 2023
Line 3:		Line 3:
	<StructureSection load='4ykq' size='340' side='right'caption='[[4ykq]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='4ykq' size='340' side='right'caption='[[4ykq]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ykr\|4ykr]], [[4ykt\|4ykt]], [[4yku\|4yku]], [[4ykw\|4ykw]], [[4ykx\|4ykx]], [[4yky\|4yky]], [[4ykz\|4ykz]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [https://pdbe.org/4ykq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [https://www.ebi.ac.uk/pdbsum/4ykq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykq ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [~~http~~://pdbe.org/4ykq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ykq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykq ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>	+	[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>

	==See Also==		==See Also==
-	*[[Heat Shock ~~Proteins~~\|Heat Shock ~~Proteins~~]]	+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kang~~, Y N~~]]	+	[[Category: Kang YN]]
-	[[Category: Stuckey~~, J A]]~~	+	[[Category: Stuckey JA]]
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Chaperone-inhibitor complex]]~~	+
-	~~[[Category: Hsp 90]]~~	+
-	~~[[Category: Protein-inhibitor complex~~]]	+

OCA at 06:51, 12 June 2019

OCA — Wed, 12 Jun 2019 06:51:06 GMT

←Older revision		Revision as of 06:51, 12 June 2019
Line 1:		Line 1:

	==Heat Shock Protein 90 Bound to CS301==		==Heat Shock Protein 90 Bound to CS301==
-	<StructureSection load='4ykq' size='340' side='right' caption='[[4ykq]], [[Resolution\|resolution]] 1.91Å' scene=''>	+	<StructureSection load='4ykq' size='340' side='right'caption='[[4ykq]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ykr\|4ykr]], [[4ykt\|4ykt]], [[4yku\|4yku]], [[4ykw\|4ykw]], [[4ykx\|4ykx]], [[4yky\|4yky]], [[4ykz\|4ykz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ykr\|4ykr]], [[4ykt\|4ykt]], [[4yku\|4yku]], [[4ykw\|4ykw]], [[4ykx\|4ykx]], [[4yky\|4yky]], [[4ykz\|4ykz]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [http://pdbe.org/4ykq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [http://www.ebi.ac.uk/pdbsum/4ykq PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [http://pdbe.org/4ykq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [http://www.ebi.ac.uk/pdbsum/4ykq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>		[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
		+
		+	==See Also==
		+	*[[Heat Shock Proteins\|Heat Shock Proteins]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Kang, Y N]]		[[Category: Kang, Y N]]
	[[Category: Stuckey, J A]]		[[Category: Stuckey, J A]]

OCA at 03:49, 10 March 2016

OCA — Thu, 10 Mar 2016 03:49:27 GMT

←Older revision		Revision as of 03:49, 10 March 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 4ykq is ~~ON HOLD until Mar 04 2017~~	+	==Heat Shock Protein 90 Bound to CS301==
-		+	<StructureSection load='4ykq' size='340' side='right' caption='[[4ykq]], [[Resolution\|resolution]] 1.91Å' scene=''>
-	~~Authors~~: ~~Kang~~, Y.N., ~~Stuckey~~, J.A.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4ykq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YKQ FirstGlance]. <br>
-	~~Description~~: ~~Heat Shock Protein 90 Bound~~ to ~~CS301~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4EO:1-(5-ETHYL-2,4-DIHYDROXYPHENYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>4EO</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ykr\|4ykr]], [[4ykt\|4ykt]], [[4yku\|4yku]], [[4ykw\|4ykw]], [[4ykx\|4ykx]], [[4yky\|4yky]], [[4ykz\|4ykz]]</td></tr>
-	[[Category: Stuckey, J.A]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ykq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykq OCA], [http://pdbe.org/4ykq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ykq RCSB], [http://www.ebi.ac.uk/pdbsum/4ykq PDBsum]</span></td></tr>
-	[[Category: ~~Kang, Y.N~~]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Kang, Y N]]
		+	[[Category: Stuckey, J A]]
		+	[[Category: Chaperone]]
		+	[[Category: Chaperone-inhibitor complex]]
		+	[[Category: Hsp 90]]
		+	[[Category: Protein-inhibitor complex]]

OCA at 23:38, 30 November 2015

OCA — Mon, 30 Nov 2015 23:38:05 GMT

←Older revision		Revision as of 23:38, 30 November 2015
Line 7:		Line 7:
	Description: Heat Shock Protein 90 Bound to CS301		Description: Heat Shock Protein 90 Bound to CS301
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Kang, Y.N]]
	[[Category: Stuckey, J.A]]		[[Category: Stuckey, J.A]]
		+	[[Category: Kang, Y.N]]

OCA at 09:28, 30 April 2015

OCA — Thu, 30 Apr 2015 09:28:23 GMT

←Older revision		Revision as of 09:28, 30 April 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ykq is ON HOLD	+	The entry 4ykq is ON HOLD until Mar 04 2017

	Authors: Kang, Y.N., Stuckey, J.A.		Authors: Kang, Y.N., Stuckey, J.A.

OCA: Protected "4ykq" [edit=sysop:move=sysop]

OCA — Wed, 11 Mar 2015 10:46:20 GMT

Protected "4ykq" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:46, 11 March 2015

OCA: New page: '''Unreleased structure''' The entry 4ykq is ON HOLD Authors: Kang, Y.N., Stuckey, J.A. Description: Heat Shock Protein 90 Bound to CS301 Category: Unreleased Structures [[Category...

OCA — Wed, 11 Mar 2015 10:46:18 GMT

New page: '''Unreleased structure''' The entry 4ykq is ON HOLD Authors: Kang, Y.N., Stuckey, J.A. Description: Heat Shock Protein 90 Bound to CS301 Category: Unreleased Structures [[Category...

New page

'''Unreleased structure'''

The entry 4ykq is ON HOLD

Authors: Kang, Y.N., Stuckey, J.A.

Description: Heat Shock Protein 90 Bound to CS301
[[Category: Unreleased Structures]]
[[Category: Kang, Y.N]]
[[Category: Stuckey, J.A]]