4yly - Revision history

OCA at 15:36, 8 November 2023

OCA — Wed, 08 Nov 2023 15:36:30 GMT

←Older revision		Revision as of 15:36, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YLY FirstGlance]. <br>		<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YLY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [https://pdbe.org/4yly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [https://www.ebi.ac.uk/pdbsum/4yly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yly ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [https://pdbe.org/4yly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [https://www.ebi.ac.uk/pdbsum/4yly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yly ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:18, 3 May 2023

OCA — Wed, 03 May 2023 08:18:23 GMT

←Older revision		Revision as of 08:18, 3 May 2023
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	<StructureSection load='4yly' size='340' side='right'caption='[[4yly]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='4yly' size='340' side='right'caption='[[4yly]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus~~ aureus~~" (rosenbach 1884) zopf 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4YLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YLY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pth ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [https://pdbe.org/4yly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [https://www.ebi.ac.uk/pdbsum/4yly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yly ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [~~http~~://pdbe.org/4yly PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4yly PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4yly ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PTH_STAAU PTH_STAAU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Aminoacyl-tRNA hydrolase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Li, X]]	+	[[Category: Staphylococcus aureus]]
-	[[Category: Song, Y]]	+	[[Category: Li X]]
-	[[Category: Teng~~, M K~~]]	+	[[Category: Song Y]]
-	[[Category: Zhang, F]]	+	[[Category: Teng MK]]
-	~~[[Category: Gram-positive]]~~	+	[[Category: Zhang F]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:07, 12 June 2019

OCA — Wed, 12 Jun 2019 07:07:56 GMT

←Older revision		Revision as of 07:07, 12 June 2019
Line 1:		Line 1:
		+
	==Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, staphylococcus aureus at 2.25 angstrom resolution==		==Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, staphylococcus aureus at 2.25 angstrom resolution==
-	<StructureSection load='4yly' size='340' side='right' caption='[[4yly]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='4yly' size='340' side='right'caption='[[4yly]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YLY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pth ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [http://pdbe.org/4yly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [http://www.ebi.ac.uk/pdbsum/4yly PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [http://pdbe.org/4yly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [http://www.ebi.ac.uk/pdbsum/4yly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yly ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 4yly" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4yly" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Peptidyl-tRNA hydrolase\|Peptidyl-tRNA hydrolase]]
	== References ==		== References ==
	<references/>		<references/>
Line 21:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Aminoacyl-tRNA hydrolase]]		[[Category: Aminoacyl-tRNA hydrolase]]
		+	[[Category: Large Structures]]
	[[Category: Li, X]]		[[Category: Li, X]]
	[[Category: Song, Y]]		[[Category: Song, Y]]

OCA at 02:13, 28 January 2016

OCA — Thu, 28 Jan 2016 02:13:59 GMT

←Older revision		Revision as of 02:13, 28 January 2016
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, staphylococcus aureus at 2.25 angstrom resolution==
		+	<StructureSection load='4yly' size='340' side='right' caption='[[4yly]], [[Resolution\|resolution]] 2.25Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4yly]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YLY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yly OCA], [http://pdbe.org/4yly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yly RCSB], [http://www.ebi.ac.uk/pdbsum/4yly PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Peptidyl-tRNA hydrolase (Pth) catalyzes the release of tRNA to relieve peptidyl-tRNA accumulation. Because Pth activity is essential for the viability of bacteria, Pth is regarded as a promising target for the discovery of new antimicrobial agents. Here, the structure of Pth from the Gram-positive bacterium Staphylococcus aureus (SaPth) was solved by X-ray crystallography at a 2.25 A resolution. The SaPth structure exhibits significant structural similarity with other members of the Pth superfamily, with a conserved alpha/beta/alpha sandwich fold. A molecular phylogenetic analysis and a structure database search indicated that SaPth is most similar to its homolog in Streptococcus pyogenes, but it has a different substrate-binding cleft state.

-	~~The entry 4yly is ON HOLD until Paper Publication~~	+	Crystal structure of Staphylococcus aureus peptidyl-tRNA hydrolase at a 2.25 A resolution.,Zhang F, Song Y, Niu L, Teng M, Li X Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):1005-10. doi:, 10.1093/abbs/gmv114. Epub 2015 Oct 26. PMID:26508479<ref>PMID:26508479</ref>

-	~~Authors: Zhang~~, F.~~, Song, Y~~.~~, Li, X., Teng, M.K~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of peptidyl~~-~~tRNA hydrolase from a Gram~~-~~positive bacterium, staphylococcus aureus at 2.25 angstrom resolution~~	+	<div class="pdbe-citations 4yly" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Aminoacyl-tRNA hydrolase]]
	[[Category: Li, X]]		[[Category: Li, X]]
	[[Category: Song, Y]]		[[Category: Song, Y]]
		+	[[Category: Teng, M K]]
	[[Category: Zhang, F]]		[[Category: Zhang, F]]
-	[[Category: ~~Teng, M.K~~]]	+	[[Category: Gram-positive]]
		+	[[Category: Hydrolase]]

OCA at 23:38, 30 November 2015

OCA — Mon, 30 Nov 2015 23:38:49 GMT

←Older revision		Revision as of 23:38, 30 November 2015
Line 7:		Line 7:
	Description: Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, staphylococcus aureus at 2.25 angstrom resolution		Description: Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, staphylococcus aureus at 2.25 angstrom resolution
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Song, Y]]
-	[[Category: Teng, M.K]]
	[[Category: Li, X]]		[[Category: Li, X]]
		+	[[Category: Song, Y]]
	[[Category: Zhang, F]]		[[Category: Zhang, F]]
		+	[[Category: Teng, M.K]]

OCA at 11:39, 1 April 2015

OCA — Wed, 01 Apr 2015 11:39:35 GMT

←Older revision		Revision as of 11:39, 1 April 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4yly is ON HOLD	+	The entry 4yly is ON HOLD until Paper Publication

	Authors: Zhang, F., Song, Y., Li, X., Teng, M.K.		Authors: Zhang, F., Song, Y., Li, X., Teng, M.K.

OCA: Protected "4yly" [edit=sysop:move=sysop]

OCA — Wed, 11 Mar 2015 10:50:01 GMT

Protected "4yly" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:50, 11 March 2015

OCA: New page: '''Unreleased structure''' The entry 4yly is ON HOLD Authors: Zhang, F., Song, Y., Li, X., Teng, M.K. Description: Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bac...

OCA — Wed, 11 Mar 2015 10:50:00 GMT

New page: '''Unreleased structure''' The entry 4yly is ON HOLD Authors: Zhang, F., Song, Y., Li, X., Teng, M.K. Description: Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bac...

New page

'''Unreleased structure'''

The entry 4yly is ON HOLD

Authors: Zhang, F., Song, Y., Li, X., Teng, M.K.

Description: Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, staphylococcus aureus at 2.25 angstrom resolution
[[Category: Unreleased Structures]]
[[Category: Song, Y]]
[[Category: Teng, M.K]]
[[Category: Li, X]]
[[Category: Zhang, F]]