4ytt - Revision history

OCA at 15:38, 8 November 2023

OCA — Wed, 08 Nov 2023 15:38:52 GMT

←Older revision		Revision as of 15:38, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_cichorii Pseudomonas cichorii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_cichorii Pseudomonas cichorii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [https://pdbe.org/4ytt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [https://www.ebi.ac.uk/pdbsum/4ytt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [https://pdbe.org/4ytt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [https://www.ebi.ac.uk/pdbsum/4ytt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytt ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:25, 10 May 2023

OCA — Wed, 10 May 2023 07:25:24 GMT

←Older revision		Revision as of 07:25, 10 May 2023
Line 3:		Line 3:
	<StructureSection load='4ytt' size='340' side='right'caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4ytt' size='340' side='right'caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacterium_cichorii"_(swingle_1925)_elliott_1930 "bacterium~~ cichorii~~" (swingle 1925) elliott 1930~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4YTT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_cichorii Pseudomonas cichorii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xsl\|4xsl]], [[4xsm\|4xsm]], [[4ytq\|4ytq]], [[4ytr\|4ytr]], [[4yts\|4yts]], [[4ytu\|4ytu]], [[4yvl\|4yvl]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [https://pdbe.org/4ytt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [https://www.ebi.ac.uk/pdbsum/4ytt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytt ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [~~http~~://pdbe.org/4ytt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ytt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytt ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DT3E_PSECI DT3E_PSECI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ishii, T]]	+	[[Category: Pseudomonas cichorii]]
-	[[Category: Izumori, K]]	+	[[Category: Ishii T]]
-	[[Category: Kamitori, S]]	+	[[Category: Izumori K]]
-	[[Category: Yoshida, H]]	+	[[Category: Kamitori S]]
-	[[Category: Yoshihara, A]]	+	[[Category: Yoshida H]]
-	~~[[Category: Epimerase]]~~	+	[[Category: Yoshihara A]]
-	~~[[Category: Isomerase~~]]	+

OCA at 08:00, 4 March 2020

OCA — Wed, 04 Mar 2020 08:00:29 GMT

←Older revision		Revision as of 08:00, 4 March 2020
Line 1:		Line 1:

	==Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with 6-deoxy L-psicose==		==Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with 6-deoxy L-psicose==
-	<StructureSection load='4ytt' size='340' side='right' caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='4ytt' size='340' side='right'caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_cichorii"_(swingle_1925)_elliott_1930 "bacterium cichorii" (swingle 1925) elliott 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_cichorii"_(swingle_1925)_elliott_1930 "bacterium cichorii" (swingle 1925) elliott 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTT FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Ishii, T]]		[[Category: Ishii, T]]
	[[Category: Izumori, K]]		[[Category: Izumori, K]]

OCA at 07:21, 13 December 2017

OCA — Wed, 13 Dec 2017 07:21:16 GMT

←Older revision		Revision as of 07:21, 13 December 2017
Line 3:		Line 3:
	<StructureSection load='4ytt' size='340' side='right' caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='4ytt' size='340' side='right' caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_cichorii"_(swingle_1925)_elliott_1930 "bacterium cichorii" (swingle 1925) elliott 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xsl\|4xsl]], [[4xsm\|4xsm]], [[4ytq\|4ytq]], [[4ytr\|4ytr]], [[4yts\|4yts]], [[4ytu\|4ytu]], [[4yvl\|4yvl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xsl\|4xsl]], [[4xsm\|4xsm]], [[4ytq\|4ytq]], [[4ytr\|4ytr]], [[4yts\|4yts]], [[4ytu\|4ytu]], [[4yvl\|4yvl]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [http://pdbe.org/4ytt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [http://www.ebi.ac.uk/pdbsum/4ytt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [http://pdbe.org/4ytt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [http://www.ebi.ac.uk/pdbsum/4ytt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytt ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
-	Pseudomonas ~~cichoriiid~~-tagatose 3-epimerase (~~P. cichoriid-TE~~) ~~can~~ efficiently ~~catalyze~~ the epimerization of not only d-tagatose to d-sorbose, but also d-fructose to d-psicose, and ~~is used for~~ the ~~production~~ of d-~~psicose from d-fructose. The crystal~~ structures of ~~P. cichoriid-TE alone and~~ in complexes with ~~d-tagatose and d-fructose~~ were determined at ~~resolutions of~~ 1~~.79~~, 2~~.28~~, and ~~2.06 A, respectively. A subunit of P. cichoriid~~-~~TE adopts a (beta/alpha)(8) barrel structure, and a metal ion (Mn(2+)) found in the active site~~ is ~~coordinated by Glu152, Asp185, His211, and Glu246 at the end of the beta-barrel. P. cichoriid-TE forms a stable dimer to give a favorable accessible surface~~ for ~~substrate binding on the front side of the dimer. The simulated omit map indicates that O2 and O3 of d-tagatose and/or d-fructose coordinate Mn(2+),~~ and that C3-~~O3 is located between carboxyl groups of Glu152 and Glu246, supporting the previously proposed mechanism of deprotonation/protonation at C3 by two Glu residues. Although the electron density is poor~~ at the 4-, 5-, and 6-positions of the ~~substrates, substrate-~~enzyme ~~interactions can be deduced from~~ the ~~significant electron density at O6~~. ~~The O6 possibly interacts with Cys66 via hydrogen bonding, whereas O4 and O5 in d~~-~~tagatose~~ and ~~O4 in d~~-~~fructose do not undergo hydrogen bonding~~ to the ~~enzyme and are~~ in a hydrophobic ~~environment created by Phe7, Trp15, Trp113, and Phe248. Due to~~ the ~~lack~~ of ~~specific interactions between~~ the ~~enzyme~~ and ~~its substrates at~~ the ~~4- and 5-positions~~, P. ~~cichoriid~~-~~TE loosely recognizes substrates~~ in ~~this region, allowing it to efficiently catalyze~~ the ~~epimerization of d-tagatose~~ and ~~d-fructose (C4 epimer~~ of ~~d-tagatose) as well. Furthermore,~~ a ~~C3-O3 proton-exchange mechanism for P. cichoriid-TE is suggested by X-ray structural analysis, providing a clear explanation for~~ the ~~regulation of the ionization state of Glu152 and Glu246~~.	+	Pseudomonas cichorii D-tagatose 3-epimerase (PcDTE), which has a broad substrate specificity, efficiently catalyzes the epimerization of not only D-tagatose to D-sorbose but also D-fructose to D-psicose (D-allulose) and also recognizes the deoxy sugars as substrates. In an attempt to elucidate the substrate recognition and catalytic reaction mechanisms of PcDTE for deoxy sugars, the X-ray structures of the PcDTE mutant form with the replacement of Cys66 by Ser (PcDTE_C66S) in complexes with deoxy sugars were determined. These X-ray structures showed that substrate recognition by the enzyme at the 1-, 2-, and 3-positions is responsible for enzymatic activity and that substrate-enzyme interactions at the 4-, 5-, and 6-positions are not essential for the catalytic reaction of the enzyme leading to the broad substrate specificity of PcDTE. They also showed that the epimerization site of 1-deoxy 3-keto D-galactitol is shifted from C3 to C4 and that 1-deoxy sugars may bind to the catalytic site in the inhibitor-binding mode. The hydrophobic groove that acts as an accessible surface for substrate binding is formed through the dimerization of PcDTE. In PcDTE_C66S/deoxy sugar complex structures, bound ligand molecules in both the linear and ring forms were detected in the hydrophobic groove, while bound ligand molecules in the catalytic site were in the linear form. This result suggests that the sugar-ring opening of a substrate may occur in the hydrophobic groove and also that the narrow channel of the passageway to the catalytic site allows a substrate in the linear form to pass through.

-	~~Crystal~~ structures of ~~D-tagatose 3-epimerase from~~ Pseudomonas cichorii ~~and its complexes with~~ D-tagatose ~~and D~~-~~fructose~~.,Yoshida H, ~~Yamada M~~, ~~Nishitani~~ T~~, Takada G~~, Izumori K, Kamitori S ~~J Mol Biol~~. ~~2007 Nov 23~~;~~374~~(2):~~443~~-53. Epub ~~2007 Sep 19~~. PMID:~~17936787~~<ref>PMID:~~17936787~~</ref>	+	X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates.,Yoshida H, Yoshihara A, Ishii T, Izumori K, Kamitori S Appl Microbiol Biotechnol. 2016 Dec;100(24):10403-10415. doi:, 10.1007/s00253-016-7673-7. Epub 2016 Jul 1. PMID:27368739<ref>PMID:27368739</ref>

	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

OCA at 12:57, 11 May 2016

OCA — Wed, 11 May 2016 12:57:08 GMT

←Older revision		Revision as of 12:57, 11 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 4ytt is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with 6-deoxy L-psicose==
		+	<StructureSection load='4ytt' size='340' side='right' caption='[[4ytt]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4ytt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTT FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PUD:6-DEOXY-L-PSICOSE'>PUD</scene>, <scene name='pdbligand=PUF:6-DEOXY-ALPHA-L-PSICOFURANOSE'>PUF</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xsl\|4xsl]], [[4xsm\|4xsm]], [[4ytq\|4ytq]], [[4ytr\|4ytr]], [[4yts\|4yts]], [[4ytu\|4ytu]], [[4yvl\|4yvl]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ytt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytt OCA], [http://pdbe.org/4ytt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ytt RCSB], [http://www.ebi.ac.uk/pdbsum/4ytt PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pseudomonas cichoriiid-tagatose 3-epimerase (P. cichoriid-TE) can efficiently catalyze the epimerization of not only d-tagatose to d-sorbose, but also d-fructose to d-psicose, and is used for the production of d-psicose from d-fructose. The crystal structures of P. cichoriid-TE alone and in complexes with d-tagatose and d-fructose were determined at resolutions of 1.79, 2.28, and 2.06 A, respectively. A subunit of P. cichoriid-TE adopts a (beta/alpha)(8) barrel structure, and a metal ion (Mn(2+)) found in the active site is coordinated by Glu152, Asp185, His211, and Glu246 at the end of the beta-barrel. P. cichoriid-TE forms a stable dimer to give a favorable accessible surface for substrate binding on the front side of the dimer. The simulated omit map indicates that O2 and O3 of d-tagatose and/or d-fructose coordinate Mn(2+), and that C3-O3 is located between carboxyl groups of Glu152 and Glu246, supporting the previously proposed mechanism of deprotonation/protonation at C3 by two Glu residues. Although the electron density is poor at the 4-, 5-, and 6-positions of the substrates, substrate-enzyme interactions can be deduced from the significant electron density at O6. The O6 possibly interacts with Cys66 via hydrogen bonding, whereas O4 and O5 in d-tagatose and O4 in d-fructose do not undergo hydrogen bonding to the enzyme and are in a hydrophobic environment created by Phe7, Trp15, Trp113, and Phe248. Due to the lack of specific interactions between the enzyme and its substrates at the 4- and 5-positions, P. cichoriid-TE loosely recognizes substrates in this region, allowing it to efficiently catalyze the epimerization of d-tagatose and d-fructose (C4 epimer of d-tagatose) as well. Furthermore, a C3-O3 proton-exchange mechanism for P. cichoriid-TE is suggested by X-ray structural analysis, providing a clear explanation for the regulation of the ionization state of Glu152 and Glu246.

-	~~Authors:~~ Yoshida, H., ~~Yoshihara~~, A., ~~Ishii, T.~~, Izumori, K., Kamitori, S.	+	Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose.,Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S J Mol Biol. 2007 Nov 23;374(2):443-53. Epub 2007 Sep 19. PMID:17936787<ref>PMID:17936787</ref>

-	~~Description: Crystal structure~~ of D-~~tagatose 3~~-~~epimerase C66S from Pseudomonas cichorii in complex with 6-deoxy L-psicose~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 4ytt" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Ishii, T]]		[[Category: Ishii, T]]
-	[[Category: Yoshihara, A]]
-	[[Category: Yoshida, H]]
-	[[Category: Kamitori, S]]
	[[Category: Izumori, K]]		[[Category: Izumori, K]]
		+	[[Category: Kamitori, S]]
		+	[[Category: Yoshida, H]]
		+	[[Category: Yoshihara, A]]
		+	[[Category: Epimerase]]
		+	[[Category: Isomerase]]

OCA at 23:44, 30 November 2015

OCA — Mon, 30 Nov 2015 23:44:32 GMT

←Older revision		Revision as of 23:44, 30 November 2015
Line 9:		Line 9:
	[[Category: Ishii, T]]		[[Category: Ishii, T]]
	[[Category: Yoshihara, A]]		[[Category: Yoshihara, A]]
-	[[Category: Kamitori, S]]
	[[Category: Yoshida, H]]		[[Category: Yoshida, H]]
		+	[[Category: Kamitori, S]]
	[[Category: Izumori, K]]		[[Category: Izumori, K]]

OCA at 09:48, 8 April 2015

OCA — Wed, 08 Apr 2015 09:48:51 GMT

←Older revision		Revision as of 09:48, 8 April 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4ytt is ON HOLD	+	The entry 4ytt is ON HOLD until Paper Publication

	Authors: Yoshida, H., Yoshihara, A., Ishii, T., Izumori, K., Kamitori, S.		Authors: Yoshida, H., Yoshihara, A., Ishii, T., Izumori, K., Kamitori, S.

OCA: Protected "4ytt" [edit=sysop:move=sysop]

OCA — Thu, 26 Mar 2015 12:50:02 GMT

Protected "4ytt" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:50, 26 March 2015

OCA: New page: '''Unreleased structure''' The entry 4ytt is ON HOLD Authors: Yoshida, H., Yoshihara, A., Ishii, T., Izumori, K., Kamitori, S. Description: Crystal structure of D-tagatose 3-epimerase ...

OCA — Thu, 26 Mar 2015 12:50:01 GMT

New page: '''Unreleased structure''' The entry 4ytt is ON HOLD Authors: Yoshida, H., Yoshihara, A., Ishii, T., Izumori, K., Kamitori, S. Description: Crystal structure of D-tagatose 3-epimerase ...

New page

'''Unreleased structure'''

The entry 4ytt is ON HOLD

Authors: Yoshida, H., Yoshihara, A., Ishii, T., Izumori, K., Kamitori, S.

Description: Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with 6-deoxy L-psicose
[[Category: Unreleased Structures]]
[[Category: Ishii, T]]
[[Category: Yoshihara, A]]
[[Category: Kamitori, S]]
[[Category: Yoshida, H]]
[[Category: Izumori, K]]