4yxa - Revision history

OCA at 08:08, 27 September 2023

OCA — Wed, 27 Sep 2023 08:08:55 GMT

←Older revision		Revision as of 08:08, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YXA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.35Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [https://pdbe.org/4yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [https://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [https://pdbe.org/4yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [https://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:29, 10 May 2023

OCA — Wed, 10 May 2023 07:29:54 GMT

←Older revision		Revision as of 07:29, 10 May 2023
Line 1:		Line 1:

	==Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein==		==Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein==
-	<StructureSection load='4yxa' size='340' side='right' caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='4yxa' size='340' side='right'caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~] and [~~http~~://en.wikipedia.org/wiki/~~Salty Salty~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4YXA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YXA FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">spaO, STM2891 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY]), orgB, STM2869 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [https://pdbe.org/4yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [https://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [~~http~~://pdbe.org/4yxa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SPAO_SALTY SPAO_SALTY]] Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells~~. [[http://www.uniprot.org/uniprot/ORGB_SALTY ORGB_SALTY]] Oxygen-regulated protein required for bacterial internalization~~.	+	[https://www.uniprot.org/uniprot/SPAO_SALTY SPAO_SALTY] Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
-	[[Category: ~~Lysozyme~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Salty~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-	[[Category: Notti~~, R Q~~]]	+	[[Category: Notti RQ]]
-	[[Category: Stebbins~~, C E]]~~	+	[[Category: Stebbins CE]]
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Type iii secretion system~~]]	+

OCA at 09:41, 22 November 2017

OCA — Wed, 22 Nov 2017 09:41:59 GMT

←Older revision		Revision as of 09:41, 22 November 2017
Line 3:		Line 3:
	<StructureSection load='4yxa' size='340' side='right' caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='4yxa' size='340' side='right' caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YXA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4] and [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YXA FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">spaO, STM2891 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY]), orgB, STM2869 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [http://pdbe.org/4yxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [http://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [http://pdbe.org/4yxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [http://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bpt4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
		+	[[Category: Salty]]
	[[Category: Notti, R Q]]		[[Category: Notti, R Q]]
	[[Category: Stebbins, C E]]		[[Category: Stebbins, C E]]
	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Type iii secretion system]]		[[Category: Type iii secretion system]]

OCA at 09:52, 10 March 2017

OCA — Fri, 10 Mar 2017 09:52:16 GMT

←Older revision		Revision as of 09:52, 10 March 2017
Line 1:		Line 1:
		+
	==Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein==		==Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein==
	<StructureSection load='4yxa' size='340' side='right' caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='4yxa' size='340' side='right' caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [http://www.ebi.ac.uk/pdbsum/4yxa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [http://pdbe.org/4yxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [http://www.ebi.ac.uk/pdbsum/4yxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yxa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4yxa" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:34, 3 June 2015

OCA — Wed, 03 Jun 2015 12:34:15 GMT

←Older revision		Revision as of 12:34, 3 June 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein==
		+	<StructureSection load='4yxa' size='340' side='right' caption='[[4yxa]], [[Resolution\|resolution]] 2.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4yxa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YXA FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yxa RCSB], [http://www.ebi.ac.uk/pdbsum/4yxa PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SPAO_SALTY SPAO_SALTY]] Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. [[http://www.uniprot.org/uniprot/ORGB_SALTY ORGB_SALTY]] Oxygen-regulated protein required for bacterial internalization.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Translocating proteins across the double membrane of Gram-negative bacteria, type III secretion systems (T3SS) occur in two evolutionarily related forms: injectisomes, delivering virulence factors into host cells, and the flagellar system, secreting the polymeric filament used for motility. While both systems share related elements of a cytoplasmic sorting platform that facilitates the hierarchical secretion of protein substrates, its assembly and regulation remain unclear. Here we describe a module mediating the assembly of the sorting platform in both secretion systems, and elucidate the structural basis for segregation of homologous components among these divergent T3SS subtypes sharing a common cytoplasmic milieu. These results provide a foundation for the subtype-specific assembly of T3SS sorting platforms and will support further mechanistic analysis and anti-virulence drug design.

-	~~The entry 4yxa is ON HOLD until Paper Publication~~	+	A common assembly module in injectisome and flagellar type III secretion sorting platforms.,Notti RQ, Bhattacharya S, Lilic M, Stebbins CE Nat Commun. 2015 May 21;6:7125. doi: 10.1038/ncomms8125. PMID:25994170<ref>PMID:25994170</ref>

-	~~Authors: Notti~~, R.Q.~~, Stebbins, C.E~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~T3SS protein 1~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: Stebbins, C.E]]	+	__TOC__
-	[[Category: ~~Notti, R.Q~~]]	+	</StructureSection>
		+	[[Category: Lysozyme]]
		+	[[Category: Notti, R Q]]
		+	[[Category: Stebbins, C E]]
		+	[[Category: Protein transport]]
		+	[[Category: Type iii secretion system]]

OCA: Protected "4yxa" [edit=sysop:move=sysop]

OCA — Wed, 01 Apr 2015 12:00:16 GMT

Protected "4yxa" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:00, 1 April 2015

OCA: New page: '''Unreleased structure''' The entry 4yxa is ON HOLD until Paper Publication Authors: Notti, R.Q., Stebbins, C.E. Description: T3SS protein 1 Category: Unreleased Structures [[Cate...

OCA — Wed, 01 Apr 2015 12:00:15 GMT

New page: '''Unreleased structure''' The entry 4yxa is ON HOLD until Paper Publication Authors: Notti, R.Q., Stebbins, C.E. Description: T3SS protein 1 Category: Unreleased Structures [[Cate...

New page

'''Unreleased structure'''

The entry 4yxa is ON HOLD until Paper Publication

Authors: Notti, R.Q., Stebbins, C.E.

Description: T3SS protein 1
[[Category: Unreleased Structures]]
[[Category: Stebbins, C.E]]
[[Category: Notti, R.Q]]