4yy0 - Revision history

OCA at 07:30, 10 May 2023

OCA — Wed, 10 May 2023 07:30:43 GMT

←Older revision		Revision as of 07:30, 10 May 2023
Line 3:		Line 3:
	<StructureSection load='4yy0' size='340' side='right'caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>		<StructureSection load='4yy0' size='340' side='right'caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~H6n1_subtype H6n1~~ subtype]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/H6N1_subtype H6N1 subtype]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4yy1\|4yy1]], [[4yy7\|4yy7]], [[4yy9\|4yy9]], [[4yya\|4yya]], [[4yyb\|4yyb]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [https://pdbe.org/4yy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [https://www.ebi.ac.uk/pdbsum/4yy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yy0 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [~~http~~://pdbe.org/4yy0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4yy0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4yy0 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0J9X268_9INFA A0A0J9X268_9INFA] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[SAAS:SAAS00842036] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324]

	==See Also==		==See Also==
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~H6n1~~ subtype]]	+	[[Category: H6N1 subtype]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bi, Y]]	+	[[Category: Bi Y]]
-	[[Category: Gao~~, G F~~]]	+	[[Category: Gao GF]]
-	[[Category: Liu, J]]	+	[[Category: Liu J]]
-	[[Category: Qi, J]]	+	[[Category: Qi J]]
-	[[Category: Shi, Y]]	+	[[Category: Shi Y]]
-	[[Category: Wang, F]]	+	[[Category: Wang F]]
-	[[Category: Wang, M]]	+	[[Category: Wang M]]
-	[[Category: Yan, J]]	+	[[Category: Yan J]]
-	[[Category: Zhang, W]]	+	[[Category: Zhang W]]
-	~~[[Category: Hemagglutinin]]~~	+
-	~~[[Category: Immune system~~]]	+

OCA at 07:41, 4 March 2020

OCA — Wed, 04 Mar 2020 07:41:32 GMT

←Older revision		Revision as of 07:41, 4 March 2020
Line 1:		Line 1:

	==The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)==		==The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)==
-	<StructureSection load='4yy0' size='340' side='right' caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>	+	<StructureSection load='4yy0' size='340' side='right'caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/H6n1_subtype H6n1 subtype]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/H6n1_subtype H6n1 subtype]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>
Line 10:		Line 10:

	==See Also==		==See Also==
-	*[[Hemagglutinin\|Hemagglutinin]]	+	*[[Hemagglutinin 3D structures\|Hemagglutinin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: H6n1 subtype]]		[[Category: H6n1 subtype]]
		+	[[Category: Large Structures]]
	[[Category: Bi, Y]]		[[Category: Bi, Y]]
	[[Category: Gao, G F]]		[[Category: Gao, G F]]

OCA at 13:03, 16 November 2017

OCA — Thu, 16 Nov 2017 13:03:47 GMT

←Older revision		Revision as of 13:03, 16 November 2017
Line 3:		Line 3:
	<StructureSection load='4yy0' size='340' side='right' caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>		<StructureSection load='4yy0' size='340' side='right' caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/H6n1_subtype H6n1 subtype]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4yy1\|4yy1]], [[4yy7\|4yy7]], [[4yy9\|4yy9]], [[4yya\|4yya]], [[4yyb\|4yyb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4yy1\|4yy1]], [[4yy7\|4yy7]], [[4yy9\|4yy9]], [[4yya\|4yya]], [[4yyb\|4yyb]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [http://pdbe.org/4yy0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yy0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yy0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [http://pdbe.org/4yy0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yy0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yy0 ProSAT]</span></td></tr>
	</table>		</table>
		+
		+	==See Also==
		+	*[[Hemagglutinin\|Hemagglutinin]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: H6n1 subtype]]
	[[Category: Bi, Y]]		[[Category: Bi, Y]]
	[[Category: Gao, G F]]		[[Category: Gao, G F]]

OCA at 04:55, 9 September 2016

OCA — Fri, 09 Sep 2016 04:55:36 GMT

←Older revision		Revision as of 04:55, 9 September 2016
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~5AX~~:2-~~(ACETYLAMINO)-1,5-ANHYDRO-2-DEOXY~~-D-~~GLUCITOL~~'>~~5AX~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4yy1\|4yy1]], [[4yy7\|4yy7]], [[4yy9\|4yy9]], [[4yya\|4yya]], [[4yyb\|4yyb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4yy1\|4yy1]], [[4yy7\|4yy7]], [[4yy9\|4yy9]], [[4yya\|4yya]], [[4yyb\|4yyb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [http://pdbe.org/4yy0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yy0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [http://pdbe.org/4yy0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yy0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yy0 ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 18:17, 10 May 2016

OCA — Tue, 10 May 2016 18:17:31 GMT

←Older revision		Revision as of 18:17, 10 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The ~~entry~~ 4yy0 ~~is ON HOLD until Paper Publication~~	+	==The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)==
-		+	<StructureSection load='4yy0' size='340' side='right' caption='[[4yy0]], [[Resolution\|resolution]] 2.59Å' scene=''>
-	~~Authors~~: ~~Wang, F~~.~~, Qi, J~~.~~, Bi, Y~~., ~~Zhang~~, W., ~~Wang~~, M., ~~Wang, M~~., ~~Liu, J~~., ~~Yan, J~~., ~~Shi, Y~~., Gao, G.F.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4yy0]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YY0 FirstGlance]. <br>
-	~~Description~~: ~~The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AX:2-(ACETYLAMINO)-1,5-ANHYDRO-2-DEOXY-D-GLUCITOL'>5AX</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4yy1\|4yy1]], [[4yy7\|4yy7]], [[4yy9\|4yy9]], [[4yya\|4yya]], [[4yyb\|4yyb]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yy0 OCA], [http://pdbe.org/4yy0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4yy0 PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bi, Y]]
		+	[[Category: Gao, G F]]
		+	[[Category: Liu, J]]
		+	[[Category: Qi, J]]
		+	[[Category: Shi, Y]]
		+	[[Category: Wang, F]]
	[[Category: Wang, M]]		[[Category: Wang, M]]
-	[[Category: ~~Gao~~, ~~G.F~~]]	+	[[Category: Yan, J]]
	[[Category: Zhang, W]]		[[Category: Zhang, W]]
-	[[Category: ~~Wang, F~~]]	+	[[Category: Hemagglutinin]]
-	[[Category: ~~Yan, J]]~~	+	[[Category: Immune system]]
-	~~[[Category: Liu, J]]~~	+
-	~~[[Category: Shi, Y]]~~	+
-	~~[[Category: Bi, Y]]~~	+
-	~~[[Category: Qi, J~~]]	+

OCA at 23:46, 30 November 2015

OCA — Mon, 30 Nov 2015 23:46:38 GMT

←Older revision		Revision as of 23:46, 30 November 2015
Line 10:		Line 10:
	[[Category: Gao, G.F]]		[[Category: Gao, G.F]]
	[[Category: Zhang, W]]		[[Category: Zhang, W]]
-	[[Category: Liu, J]]
-	[[Category: Shi, Y]]
	[[Category: Wang, F]]		[[Category: Wang, F]]
	[[Category: Yan, J]]		[[Category: Yan, J]]
		+	[[Category: Liu, J]]
		+	[[Category: Shi, Y]]
	[[Category: Bi, Y]]		[[Category: Bi, Y]]
	[[Category: Qi, J]]		[[Category: Qi, J]]

OCA at 09:47, 30 April 2015

OCA — Thu, 30 Apr 2015 09:47:56 GMT

←Older revision		Revision as of 09:47, 30 April 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4yy0 is ON HOLD	+	The entry 4yy0 is ON HOLD until Paper Publication

	Authors: Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.		Authors: Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.

OCA: Protected "4yy0" [edit=sysop:move=sysop]

OCA — Wed, 01 Apr 2015 12:02:10 GMT

Protected "4yy0" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:02, 1 April 2015

OCA: New page: '''Unreleased structure''' The entry 4yy0 is ON HOLD Authors: Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F. Description: The structure o...

OCA — Wed, 01 Apr 2015 12:02:08 GMT

New page: '''Unreleased structure''' The entry 4yy0 is ON HOLD Authors: Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F. Description: The structure o...

New page

'''Unreleased structure'''

The entry 4yy0 is ON HOLD

Authors: Wang, F., Qi, J., Bi, Y., Zhang, W., Wang, M., Wang, M., Liu, J., Yan, J., Shi, Y., Gao, G.F.

Description: The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013)
[[Category: Unreleased Structures]]
[[Category: Wang, M]]
[[Category: Gao, G.F]]
[[Category: Zhang, W]]
[[Category: Liu, J]]
[[Category: Shi, Y]]
[[Category: Wang, F]]
[[Category: Yan, J]]
[[Category: Bi, Y]]
[[Category: Qi, J]]