4zhw - Revision history

OCA at 15:44, 8 November 2023

OCA — Wed, 08 Nov 2023 15:44:47 GMT

←Older revision		Revision as of 15:44, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>		<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [https://pdbe.org/4zhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [https://www.ebi.ac.uk/pdbsum/4zhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhw ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.391Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [https://pdbe.org/4zhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [https://www.ebi.ac.uk/pdbsum/4zhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:28, 18 May 2023

OCA — Thu, 18 May 2023 07:28:28 GMT

←Older revision		Revision as of 07:28, 18 May 2023
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	<StructureSection load='4zhw' size='340' side='right'caption='[[4zhw]], [[Resolution\|resolution]] 1.39Å' scene=''>		<StructureSection load='4zhw' size='340' side='right'caption='[[4zhw]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4zhu\|4zhu]], [[4zhv\|4zhv]], [[4zhy\|4zhy]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [https://pdbe.org/4zhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [https://www.ebi.ac.uk/pdbsum/4zhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhw ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfiB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>~~	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [~~http~~://pdbe.org/4zhw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4zhw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhw ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9I4L6_PSEAE Q9I4L6_PSEAE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Bartlam, M]]	+	[[Category: Bartlam M]]
-	[[Category: Li, S]]	+	[[Category: Li S]]
-	[[Category: Li, T]]	+	[[Category: Li T]]
-	[[Category: Wang, Y]]	+	[[Category: Wang Y]]
-	~~[[Category: Outer membrane protein]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Signalling~~]]	+

OCA at 07:05, 19 June 2019

OCA — Wed, 19 Jun 2019 07:05:01 GMT

←Older revision		Revision as of 07:05, 19 June 2019
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	==Crystal structure of a bacterial signalling protein (N-terminal truncation)==		==Crystal structure of a bacterial signalling protein (N-terminal truncation)==
-	<StructureSection load='4zhw' size='340' side='right' caption='[[4zhw]], [[Resolution\|resolution]] 1.39Å' scene=''>	+	<StructureSection load='4zhw' size='340' side='right'caption='[[4zhw]], [[Resolution\|resolution]] 1.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4zhu\|4zhu]], [[4zhv\|4zhv]], [[4zhy\|4zhy]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4zhu\|4zhu]], [[4zhv\|4zhv]], [[4zhy\|4zhy]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [http://pdbe.org/4zhw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [http://www.ebi.ac.uk/pdbsum/4zhw PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">yfiB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [http://pdbe.org/4zhw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [http://www.ebi.ac.uk/pdbsum/4zhw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zhw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Pseae]]
	[[Category: Bartlam, M]]		[[Category: Bartlam, M]]
	[[Category: Li, S]]		[[Category: Li, S]]

OCA at 11:58, 13 May 2016

OCA — Fri, 13 May 2016 11:58:39 GMT

←Older revision		Revision as of 11:58, 13 May 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 4zhw is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of a bacterial signalling protein (N-terminal truncation)==
		+	<StructureSection load='4zhw' size='340' side='right' caption='[[4zhw]], [[Resolution\|resolution]] 1.39Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4zhw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZHW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZHW FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4zhu\|4zhu]], [[4zhv\|4zhv]], [[4zhy\|4zhy]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zhw OCA], [http://pdbe.org/4zhw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zhw RCSB], [http://www.ebi.ac.uk/pdbsum/4zhw PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	YfiBNR is a tripartite signalling system in Pseudomonas aeruginosa that modulates intracellular c-di-GMP levels in response to signals received in the periplasm. YfiB is an outer membrane lipoprotein and presumed sensor protein that sequesters the repressor protein YfiR. To provide insights into YfiBNR function, we have determined three-dimensional crystal structures of YfiB and YfiR from P. aeruginosa PAO1 alone and as a 1:1 complex. A YfiB(27-168) construct is predominantly dimeric, whereas a YfiB(59-168) is monomeric, indicating that YfiB can dimerize via its N-terminal region. YfiR forms a stable complex with YfiB(59-168), while the YfiR binding interface is obstructed by the N-terminal region in YfiB(27-168). The YfiB-YfiR complex reveals a conserved interaction surface on YfiR that overlaps with residues predicted to interact with the periplasmic PAS domain of YfiN. Comparison of native and YfiR-bound structures of YfiB suggests unwinding of the N-terminal linker region for attachment to the outer membrane. A model is thus proposed for YfiR sequestration at the outer membrane by YfiB. Our work provides the first detailed insights into the interaction between YfiB and YfiR at the molecular level and is a valuable starting point for further functional and mechanistic studies of the YfiBNR signalling system.

-	~~Authors: Li, S~~., Li, T., ~~Wang~~, Y., Bartlam, M.	+	Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1.,Li S, Li T, Xu Y, Zhang Q, Zhang W, Che S, Liu R, Wang Y, Bartlam M Sci Rep. 2015 Nov 23;5:16915. doi: 10.1038/srep16915. PMID:26593397<ref>PMID:26593397</ref>

-	~~Description: Crystal structure of~~ a ~~bacterial signalling protein (N~~-~~terminal truncation)~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 4zhw" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bartlam, M]]
	[[Category: Li, S]]		[[Category: Li, S]]
	[[Category: Li, T]]		[[Category: Li, T]]
	[[Category: Wang, Y]]		[[Category: Wang, Y]]
-	[[Category: ~~Bartlam, M~~]]	+	[[Category: Outer membrane protein]]
		+	[[Category: Signaling protein]]
		+	[[Category: Signalling]]

OCA at 09:09, 9 December 2015

OCA — Wed, 09 Dec 2015 09:09:41 GMT

←Older revision		Revision as of 09:09, 9 December 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4zhw is ON HOLD	+	The entry 4zhw is ON HOLD until Paper Publication

	Authors: Li, S., Li, T., Wang, Y., Bartlam, M.		Authors: Li, S., Li, T., Wang, Y., Bartlam, M.

OCA: Protected "4zhw" [edit=sysop:move=sysop]

OCA — Wed, 06 May 2015 11:44:50 GMT

Protected "4zhw" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:44, 6 May 2015

OCA: New page: '''Unreleased structure''' The entry 4zhw is ON HOLD Authors: Li, S., Li, T., Wang, Y., Bartlam, M. Description: Crystal structure of a bacterial signalling protein (N-terminal truncat...

OCA — Wed, 06 May 2015 11:44:48 GMT

New page: '''Unreleased structure''' The entry 4zhw is ON HOLD Authors: Li, S., Li, T., Wang, Y., Bartlam, M. Description: Crystal structure of a bacterial signalling protein (N-terminal truncat...

New page

'''Unreleased structure'''

The entry 4zhw is ON HOLD

Authors: Li, S., Li, T., Wang, Y., Bartlam, M.

Description: Crystal structure of a bacterial signalling protein (N-terminal truncation)
[[Category: Unreleased Structures]]
[[Category: Li, S]]
[[Category: Li, T]]
[[Category: Wang, Y]]
[[Category: Bartlam, M]]