4zkp - Revision history

OCA at 08:19, 27 September 2023

OCA — Wed, 27 Sep 2023 08:19:34 GMT

←Older revision		Revision as of 08:19, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>		<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [https://pdbe.org/4zkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [https://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [https://pdbe.org/4zkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [https://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:31, 18 May 2023

OCA — Thu, 18 May 2023 07:31:42 GMT

←Older revision		Revision as of 07:31, 18 May 2023
Line 3:		Line 3:
	<StructureSection load='4zkp' size='340' side='right'caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4zkp' size='340' side='right'caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bpp22 Bpp22~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [https://pdbe.org/4zkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [https://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10754 BPP22])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [~~http~~://pdbe.org/4zkp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NEEDL_BPP22 NEEDL_BPP22]] Cell-perforating component and plug protein of the phage tail machine. Host cell membrane perforation allows viral DNA ejection. Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters.<ref>PMID:18059287</ref> <ref>PMID:20817910</ref>	+	[https://www.uniprot.org/uniprot/NEEDL_BPP22 NEEDL_BPP22] Cell-perforating component and plug protein of the phage tail machine. Host cell membrane perforation allows viral DNA ejection. Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters.<ref>PMID:18059287</ref> <ref>PMID:20817910</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bpp22]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Cingolani, G]]~~	+	[[Category: Salmonella virus P22]]
-	~~[[Category: Sankhala, R S]]~~	+	[[Category: Cingolani G]]
-	~~[[Category: Membrane penetration]]~~	+	[[Category: Sankhala RS]]
-	~~[[Category:~~ P22]]	+
-	[[Category: ~~Tail needle~~]]	+
-	[[Category: ~~Viral protein~~]]	+

OCA at 11:00, 25 December 2019

OCA — Wed, 25 Dec 2019 11:00:19 GMT

←Older revision		Revision as of 11:00, 25 December 2019
Line 3:		Line 3:
	<StructureSection load='4zkp' size='340' side='right'caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4zkp' size='340' side='right'caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpp22 Bpp22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10754 BPP22])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://pdbe.org/4zkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://pdbe.org/4zkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>
	</table>		</table>
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bpp22]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cingolani, G]]		[[Category: Cingolani, G]]

OCA at 06:54, 10 July 2019

OCA — Wed, 10 Jul 2019 06:54:56 GMT

←Older revision		Revision as of 06:54, 10 July 2019
Line 1:		Line 1:

	==P22 Tail Needle Gp26 crystallized at pH 7.0==		==P22 Tail Needle Gp26 crystallized at pH 7.0==
-	<StructureSection load='4zkp' size='340' side='right' caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='4zkp' size='340' side='right'caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>		<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Cingolani, G]]		[[Category: Cingolani, G]]
	[[Category: Sankhala, R S]]		[[Category: Sankhala, R S]]

OCA at 06:20, 6 October 2017

OCA — Fri, 06 Oct 2017 06:20:12 GMT

←Older revision		Revision as of 06:20, 6 October 2017
Line 1:		Line 1:
		+
	==P22 Tail Needle Gp26 crystallized at pH 7.0==		==P22 Tail Needle Gp26 crystallized at pH 7.0==
	<StructureSection load='4zkp' size='340' side='right' caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4zkp' size='340' side='right' caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://pdbe.org/4zkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://pdbe.org/4zkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 10:07, 2 December 2015

OCA — Wed, 02 Dec 2015 10:07:49 GMT

←Older revision		Revision as of 10:07, 2 December 2015
Line 9:		Line 9:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/NEEDL_BPP22 NEEDL_BPP22]] Cell-perforating component and plug protein of the phage tail machine. Host cell membrane perforation allows viral DNA ejection. Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters.<ref>PMID:18059287</ref> <ref>PMID:20817910</ref>		[[http://www.uniprot.org/uniprot/NEEDL_BPP22 NEEDL_BPP22]] Cell-perforating component and plug protein of the phage tail machine. Host cell membrane perforation allows viral DNA ejection. Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters.<ref>PMID:18059287</ref> <ref>PMID:20817910</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial viruses of the P22-like family encode a specialized tail needle essential for genome stabilization after DNA-packaging and implicated in Gram-negative cell envelope penetration. The atomic structure of P22 tail needle (gp26) crystallized at acidic pH reveals a slender fiber containing an N-terminal trimer-of-hairpins tip. Though the length and composition of tail needles vary significantly in Podoviridae, unexpectedly, the amino acid sequence of the N-terminal tip is exceptionally conserved in more than two hundred genomes of P22-like phages and prophages. In this paper, we used X-ray crystallography and EM to investigate the neutral pH structure of three tail needles from bacteriophage P22, HK620 and Sf6. In all cases, we found the N-terminal tip is poorly structured, in stark contrast to the compact trimer-of-hairpins seen in gp26 crystallized at acidic pH. Hydrogen/deuterium exchange mass spectrometry, limited proteolysis, circular dichroism spectroscopy and gel filtration chromatography revealed that the N-terminal tip is highly dynamic in solution and unlikely to adopt a stable trimeric conformation at physiological pH. This is supported by the cryo-EM reconstruction of P22 mature virion tail, where the density of gp26 N-terminal tip is incompatible with a trimer-of-hairpins. We propose the tail needle N-terminal tip exists in two conformations: a pre-ejection extended conformation, which seals the portal vertex after genome-packaging and a post-ejection trimer-of-hairpins that form upon its release from the virion. The conformational plasticity of the tail needle N-terminal tip is built in the amino acid sequence, explaining its extraordinary conservation in nature.
		+
		+	Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions.,Bhardwaj A, Sankhala RS, Olia AS, Brooke D, Casjens SR, Taylor DJ, Prevelige PE Jr, Cingolani G J Biol Chem. 2015 Nov 16. pii: jbc.M115.696260. PMID:26574546<ref>PMID:26574546</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4zkp" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:00, 30 November 2015

OCA — Mon, 30 Nov 2015 19:00:08 GMT

←Older revision		Revision as of 19:00, 30 November 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://pdbe.org/4zkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 14:52, 29 July 2015

OCA — Wed, 29 Jul 2015 14:52:19 GMT

←Older revision		Revision as of 14:52, 29 July 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==P22 Tail Needle Gp26 crystallized at pH 7.0==
-		+	<StructureSection load='4zkp' size='340' side='right' caption='[[4zkp]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~The entry~~ 4zkp is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4zkp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZKP FirstGlance]. <br>
-	~~Authors~~: ~~Sankhala, R~~.S.~~, Cingolani, G~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2poh\|2poh]], [[3c9i\|3c9i]]</td></tr>
-	~~Description~~: ~~P22 Tail Needle Gp26 crystallized at pH 7~~.0	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zkp RCSB], [http://www.ebi.ac.uk/pdbsum/4zkp PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Sankhala~~, R.S]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NEEDL_BPP22 NEEDL_BPP22]] Cell-perforating component and plug protein of the phage tail machine. Host cell membrane perforation allows viral DNA ejection. Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters.<ref>PMID:18059287</ref> <ref>PMID:20817910</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cingolani, G]]		[[Category: Cingolani, G]]
		+	[[Category: Sankhala, R S]]
		+	[[Category: Membrane penetration]]
		+	[[Category: P22]]
		+	[[Category: Tail needle]]
		+	[[Category: Viral protein]]

OCA: Protected "4zkp" [edit=sysop:move=sysop]

OCA — Wed, 06 May 2015 11:53:21 GMT

Protected "4zkp" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:53, 6 May 2015

OCA: New page: '''Unreleased structure''' The entry 4zkp is ON HOLD Authors: Sankhala, R.S., Cingolani, G. Description: P22 Tail Needle Gp26 crystallized at pH 7.0 Category: Unreleased Structures...

OCA — Wed, 06 May 2015 11:53:19 GMT

New page: '''Unreleased structure''' The entry 4zkp is ON HOLD Authors: Sankhala, R.S., Cingolani, G. Description: P22 Tail Needle Gp26 crystallized at pH 7.0 Category: Unreleased Structures...

New page

'''Unreleased structure'''

The entry 4zkp is ON HOLD

Authors: Sankhala, R.S., Cingolani, G.

Description: P22 Tail Needle Gp26 crystallized at pH 7.0
[[Category: Unreleased Structures]]
[[Category: Sankhala, R.S]]
[[Category: Cingolani, G]]