5a0o - Revision history

OCA at 11:02, 10 January 2024

OCA — Wed, 10 Jan 2024 11:02:14 GMT

←Older revision		Revision as of 11:02, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A0O FirstGlance]. <br>		<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A0O FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [https://pdbe.org/5a0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [https://www.ebi.ac.uk/pdbsum/5a0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a0o ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.73Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [https://pdbe.org/5a0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [https://www.ebi.ac.uk/pdbsum/5a0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a0o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:50, 18 May 2023

OCA — Thu, 18 May 2023 07:50:59 GMT

←Older revision		Revision as of 07:50, 18 May 2023
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	<StructureSection load='5a0o' size='340' side='right'caption='[[5a0o]], [[Resolution\|resolution]] 2.73Å' scene=''>		<StructureSection load='5a0o' size='340' side='right'caption='[[5a0o]], [[Resolution\|resolution]] 2.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Synthetic_construct_sequences~~ Synthetic construct ~~sequences~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5A0O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A0O FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [~~http~~://pdbe.org/5a0o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5a0o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5a0o ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [https://pdbe.org/5a0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [https://www.ebi.ac.uk/pdbsum/5a0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a0o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Synthetic construct ~~sequences~~]]	+	[[Category: Synthetic construct]]
-	[[Category: Breeze~~, A L~~]]	+	[[Category: Breeze AL]]
-	[[Category: Burslem~~, G M~~]]	+	[[Category: Burslem GM]]
-	[[Category: Edwards~~, T A~~]]	+	[[Category: Edwards TA]]
-	[[Category: Kyle~~, H F~~]]	+	[[Category: Kyle HF]]
-	[[Category: Nelson, A]]	+	[[Category: Nelson A]]
-	[[Category: Stott, J]]	+	[[Category: Stott J]]
-	[[Category: Tiede, C]]	+	[[Category: Tiede C]]
-	[[Category: Tomlinson~~, D C~~]]	+	[[Category: Tomlinson DC]]
-	[[Category: Warriner~~, S L~~]]	+	[[Category: Warriner SL]]
-	[[Category: Wickson~~, K F~~]]	+	[[Category: Wickson KF]]
-	[[Category: Wilson~~, A J]]~~	+	[[Category: Wilson AJ]]
-	~~[[Category: Affimer]]~~	+
-	~~[[Category: De novo protein~~]]	+

OCA at 08:32, 26 June 2019

OCA — Wed, 26 Jun 2019 08:32:14 GMT

←Older revision		Revision as of 08:32, 26 June 2019
Line 1:		Line 1:
		+
	==adhiron raised against p300==		==adhiron raised against p300==
-	<StructureSection load='5a0o' size='340' side='right' caption='[[5a0o]], [[Resolution\|resolution]] 2.73Å' scene=''>	+	<StructureSection load='5a0o' size='340' side='right'caption='[[5a0o]], [[Resolution\|resolution]] 2.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0O FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [http://pdbe.org/5a0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [http://www.ebi.ac.uk/pdbsum/5a0o PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [http://pdbe.org/5a0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [http://www.ebi.ac.uk/pdbsum/5a0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a0o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Synthetic construct sequences]]
	[[Category: Breeze, A L]]		[[Category: Breeze, A L]]
	[[Category: Burslem, G M]]		[[Category: Burslem, G M]]

OCA at 07:34, 30 September 2015

OCA — Wed, 30 Sep 2015 07:34:58 GMT

←Older revision		Revision as of 07:34, 30 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0O FirstGlance]. <br>		<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0O FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [http://www.ebi.ac.uk/pdbsum/5a0o PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [http://pdbe.org/5a0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [http://www.ebi.ac.uk/pdbsum/5a0o PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 5a0o" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:23, 15 July 2015

OCA — Wed, 15 Jul 2015 13:23:35 GMT

←Older revision		Revision as of 13:23, 15 July 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==adhiron raised against p300==
		+	<StructureSection load='5a0o' size='340' side='right' caption='[[5a0o]], [[Resolution\|resolution]] 2.73Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5a0o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0O FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a0o RCSB], [http://www.ebi.ac.uk/pdbsum/5a0o PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The HIF-1alpha/p300 protein-protein interaction plays a key role in tumor metabolism and thus represents a high value target for anticancer drug-development. Although several studies have identified inhibitor candidates using rationale design, more detailed understanding of the interaction and binding interface is necessary to inform development of superior inhibitors. In this work, we report a detailed biophysical analysis of the native interaction with both peptide and Adhiron phage display experiments to identify novel binding motifs and binding regions of the surface of p300 to inform future inhibitor design.

-	~~The entry 5a0o is ON HOLD until Paper Publication~~	+	Exploration of the HIF-1alpha/p300 interface using peptide and Adhiron phage display technologies.,Kyle HF, Wickson KF, Stott J, Burslem GM, Breeze AL, Tiede C, Tomlinson DC, Warriner SL, Nelson A, Wilson AJ, Edwards TA Mol Biosyst. 2015 Jul 2. PMID:26135796<ref>PMID:26135796</ref>

-	~~Authors: Kyle~~, H.~~F., Wickson, K.F., Stott, J., Burslem, G.M., Breeze, A.L., Tiede, C., Tomlinson, D.C., Warriner,~~ S.~~L., Nelson, A., Wilson, A.J., Edwards, T.A~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: adhiron raised against p300~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: Burslem, G.M]]	+	__TOC__
-	[[Category: ~~Wickson~~, K.F]]	+	</StructureSection>
-	[[Category: ~~Tomlinson~~, ~~D.C~~]]	+	[[Category: Breeze, A L]]
		+	[[Category: Burslem, G M]]
		+	[[Category: Edwards, T A]]
		+	[[Category: Kyle, H F]]
		+	[[Category: Nelson, A]]
	[[Category: Stott, J]]		[[Category: Stott, J]]
-	[[Category: Breeze, A.L]]
-	[[Category: Nelson, A]]
-	[[Category: Warriner, S.L]]
-	[[Category: Edwards, T.A]]
	[[Category: Tiede, C]]		[[Category: Tiede, C]]
-	[[Category: Wilson, A.J]]	+	[[Category: Tomlinson, D C]]
-	[[Category: ~~Kyle, H.F~~]]	+	[[Category: Warriner, S L]]
		+	[[Category: Wickson, K F]]
		+	[[Category: Wilson, A J]]
		+	[[Category: Affimer]]
		+	[[Category: De novo protein]]

OCA: Protected "5a0o" [edit=sysop:move=sysop]

OCA — Thu, 30 Apr 2015 10:27:06 GMT

Protected "5a0o" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:27, 30 April 2015

OCA: New page: '''Unreleased structure''' The entry 5a0o is ON HOLD until Paper Publication Authors: Kyle, H.F., Wickson, K.F., Stott, J., Burslem, G.M., Breeze, A.L., Tiede, C., Tomlinson, D.C., Warr...

OCA — Thu, 30 Apr 2015 10:27:05 GMT

New page: '''Unreleased structure''' The entry 5a0o is ON HOLD until Paper Publication Authors: Kyle, H.F., Wickson, K.F., Stott, J., Burslem, G.M., Breeze, A.L., Tiede, C., Tomlinson, D.C., Warr...

New page

'''Unreleased structure'''

The entry 5a0o is ON HOLD until Paper Publication

Authors: Kyle, H.F., Wickson, K.F., Stott, J., Burslem, G.M., Breeze, A.L., Tiede, C., Tomlinson, D.C., Warriner, S.L., Nelson, A., Wilson, A.J., Edwards, T.A.

Description: adhiron raised against p300
[[Category: Unreleased Structures]]
[[Category: Burslem, G.M]]
[[Category: Wickson, K.F]]
[[Category: Tomlinson, D.C]]
[[Category: Stott, J]]
[[Category: Breeze, A.L]]
[[Category: Nelson, A]]
[[Category: Warriner, S.L]]
[[Category: Edwards, T.A]]
[[Category: Tiede, C]]
[[Category: Wilson, A.J]]
[[Category: Kyle, H.F]]