5a5p - Revision history

OCA at 11:37, 9 May 2024

OCA — Thu, 09 May 2024 11:37:44 GMT

←Older revision		Revision as of 11:37, 9 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A5P FirstGlance]. <br>		<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A5P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.03Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [https://pdbe.org/5a5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [https://www.ebi.ac.uk/pdbsum/5a5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [https://pdbe.org/5a5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [https://www.ebi.ac.uk/pdbsum/5a5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5p ProSAT]</span></td></tr>
	</table>		</table>

OCA at 04:40, 25 May 2023

OCA — Thu, 25 May 2023 04:40:28 GMT

←Older revision		Revision as of 04:40, 25 May 2023
Line 3:		Line 3:
	<StructureSection load='5a5p' size='340' side='right'caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>		<StructureSection load='5a5p' size='340' side='right'caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5A5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A5P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5a5n\|5a5n]], [[5a5o\|5a5o]], [[5a5q\|5a5q]], [[5a5r\|5a5r]], [[5a5s\|5a5s]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [https://pdbe.org/5a5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [https://www.ebi.ac.uk/pdbsum/5a5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5p ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosinetriphosphatase Adenosinetriphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.3 3.6.1.3] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [~~http~~://pdbe.org/5a5p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5a5p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5p ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN]] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref>	+	[https://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Adenosinetriphosphatase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bamborough, P]]	+	[[Category: Bamborough P]]
-	[[Category: Chung, C]]	+	[[Category: Chung C]]
-	[[Category: Demont, E]]	+	[[Category: Demont E]]
-	~~[[Category: Atad2]]~~	+
-	~~[[Category: Atpase family aaa domain-containing protein 2]]~~	+
-	~~[[Category: Bromodomain]]~~	+
-	~~[[Category: Epigenetic]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Inhibitor~~]]	+

OCA at 08:45, 26 June 2019

OCA — Wed, 26 Jun 2019 08:45:36 GMT

←Older revision		Revision as of 08:45, 26 June 2019
Line 1:		Line 1:

	==Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one==		==Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one==
-	<StructureSection load='5a5p' size='340' side='right' caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>	+	<StructureSection load='5a5p' size='340' side='right'caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A5P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5a5n\|5a5n]], [[5a5o\|5a5o]], [[5a5q\|5a5q]], [[5a5r\|5a5r]], [[5a5s\|5a5s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5a5n\|5a5n]], [[5a5o\|5a5o]], [[5a5q\|5a5q]], [[5a5r\|5a5r]], [[5a5s\|5a5s]]</td></tr>
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 5a5p" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5a5p" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ATPase family AAA domain-containing protein\|ATPase family AAA domain-containing protein]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Adenosinetriphosphatase]]		[[Category: Adenosinetriphosphatase]]
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Bamborough, P]]		[[Category: Bamborough, P]]
	[[Category: Chung, C]]		[[Category: Chung, C]]

OCA at 13:21, 10 May 2017

OCA — Wed, 10 May 2017 13:21:26 GMT

←Older revision		Revision as of 13:21, 10 May 2017
Line 1:		Line 1:
		+
	==Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one==		==Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one==
	<StructureSection load='5a5p' size='340' side='right' caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>		<StructureSection load='5a5p' size='340' side='right' caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5a5n\|5a5n]], [[5a5o\|5a5o]], [[5a5q\|5a5q]], [[5a5r\|5a5r]], [[5a5s\|5a5s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5a5n\|5a5n]], [[5a5o\|5a5o]], [[5a5q\|5a5q]], [[5a5r\|5a5r]], [[5a5s\|5a5s]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosinetriphosphatase Adenosinetriphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.3 3.6.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosinetriphosphatase Adenosinetriphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.3 3.6.1.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [http://www.ebi.ac.uk/pdbsum/5a5p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [http://pdbe.org/5a5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [http://www.ebi.ac.uk/pdbsum/5a5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a5p ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 5a5p" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:07, 22 July 2015

OCA — Wed, 22 Jul 2015 14:07:03 GMT

←Older revision		Revision as of 14:07, 22 July 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one==
		+	<StructureSection load='5a5p' size='340' side='right' caption='[[5a5p]], [[Resolution\|resolution]] 2.03Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5a5p]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A5P FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JTF:8-{[2-(DIMETHYLAMINO)ETHYL]AMINO}-3-METHYL-1,2-DIHYDROQUINOLIN-2-ONE'>JTF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5a5n\|5a5n]], [[5a5o\|5a5o]], [[5a5q\|5a5q]], [[5a5r\|5a5r]], [[5a5s\|5a5s]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosinetriphosphatase Adenosinetriphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.3 3.6.1.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a5p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a5p RCSB], [http://www.ebi.ac.uk/pdbsum/5a5p PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN]] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Overexpression of ATAD2 (ATPase family, AAA domain containing 2) has been linked to disease severity and progression in a wide range of cancers, and is implicated in the regulation of several drivers of cancer growth. Little is known of the dependence of these effects upon the ATAD2 bromodomain, which has been categorized as among the least tractable of its class. The absence of any potent, selective inhibitors limits clear understanding of the therapeutic potential of the bromodomain. Here, we describe the discovery of a hit from a fragment-based targeted array. Optimization of this produced the first known micromolar inhibitors of the ATAD2 bromodomain.

-	~~The entry 5a5p is ON HOLD~~	+	Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.,Demont EH, Chung CW, Furze RC, Grandi P, Michon AM, Wellaway C, Barrett N, Bridges AM, Craggs PD, Diallo H, Dixon DP, Douault C, Emmons AJ, Jones EJ, Karamshi BV, Locke K, Mitchell DJ, Mouzon BH, Prinjha RK, Roberts AD, Sheppard RJ, Watson RJ, Bamborough P J Med Chem. 2015 Jul 9. PMID:26155854<ref>PMID:26155854</ref>

-	~~Authors: Chung~~, C.~~, Bamborough, P~~.~~, Demont, E~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of human ATAD2 bromodomain in complex with 8-2-( dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Adenosinetriphosphatase]]
		+	[[Category: Bamborough, P]]
	[[Category: Chung, C]]		[[Category: Chung, C]]
	[[Category: Demont, E]]		[[Category: Demont, E]]
-	[[Category: ~~Bamborough, P~~]]	+	[[Category: Atad2]]
		+	[[Category: Atpase family aaa domain-containing protein 2]]
		+	[[Category: Bromodomain]]
		+	[[Category: Epigenetic]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]

OCA: Protected "5a5p" [edit=sysop:move=sysop]

OCA — Wed, 01 Jul 2015 10:28:22 GMT

Protected "5a5p" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:28, 1 July 2015

OCA: New page: '''Unreleased structure''' The entry 5a5p is ON HOLD Authors: Chung, C., Bamborough, P., Demont, E. Description: Crystal structure of human ATAD2 bromodomain in complex with 8-2-( dime...

OCA — Wed, 01 Jul 2015 10:28:21 GMT

New page: '''Unreleased structure''' The entry 5a5p is ON HOLD Authors: Chung, C., Bamborough, P., Demont, E. Description: Crystal structure of human ATAD2 bromodomain in complex with 8-2-( dime...

New page

'''Unreleased structure'''

The entry 5a5p is ON HOLD

Authors: Chung, C., Bamborough, P., Demont, E.

Description: Crystal structure of human ATAD2 bromodomain in complex with 8-2-( dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one
[[Category: Unreleased Structures]]
[[Category: Chung, C]]
[[Category: Demont, E]]
[[Category: Bamborough, P]]