5ajt - Revision history

OCA at 11:11, 10 January 2024

OCA — Wed, 10 Jan 2024 11:11:13 GMT

←Older revision		Revision as of 11:11, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Claviceps_purpurea Claviceps purpurea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJT FirstGlance]. <br>		<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Claviceps_purpurea Claviceps purpurea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.43Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [https://pdbe.org/5ajt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [https://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [https://pdbe.org/5ajt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [https://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>
	</table>		</table>

OCA at 05:04, 25 May 2023

OCA — Thu, 25 May 2023 05:04:32 GMT

←Older revision		Revision as of 05:04, 25 May 2023
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	<StructureSection load='5ajt' size='340' side='right'caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>		<StructureSection load='5ajt' size='340' side='right'caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Clapu Clapu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5AJT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Claviceps_purpurea Claviceps purpurea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aju\|5aju]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [https://pdbe.org/5ajt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [https://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [~~http~~://pdbe.org/5ajt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/M1VUY5_CLAP2 M1VUY5_CLAP2]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Clapu~~]]	+	[[Category: Claviceps purpurea]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dzurova, L]]	+	[[Category: Dzurova L]]
-	[[Category: Forneris, F]]	+	[[Category: Forneris F]]
-	[[Category: Savino, S]]	+	[[Category: Savino S]]
-	~~[[Category: Cytokinin]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Lysine decarboxylase]]~~	+
-	~~[[Category: Rossmann fold~~]]	+

OCA at 07:18, 26 June 2019

OCA — Wed, 26 Jun 2019 07:18:21 GMT

←Older revision		Revision as of 07:18, 26 June 2019
Line 1:		Line 1:

	==Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea==		==Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea==
-	<StructureSection load='5ajt' size='340' side='right' caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>	+	<StructureSection load='5ajt' size='340' side='right'caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clapu Clapu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO~~</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT~~</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aju\|5aju]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aju\|5aju]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [http://pdbe.org/5ajt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [http://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [http://pdbe.org/5ajt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [http://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Clapu]]
		+	[[Category: Large Structures]]
	[[Category: Dzurova, L]]		[[Category: Dzurova, L]]
	[[Category: Forneris, F]]		[[Category: Forneris, F]]

OCA at 13:18, 10 May 2017

OCA — Wed, 10 May 2017 13:18:51 GMT

←Older revision		Revision as of 13:18, 10 May 2017
Line 1:		Line 1:
		+
	==Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea==		==Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea==
	<StructureSection load='5ajt' size='340' side='right' caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>		<StructureSection load='5ajt' size='340' side='right' caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aju\|5aju]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aju\|5aju]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [http://www.ebi.ac.uk/pdbsum/5ajt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [http://pdbe.org/5ajt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [http://www.ebi.ac.uk/pdbsum/5ajt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajt ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 5ajt" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:31, 3 June 2015

OCA — Wed, 03 Jun 2015 12:31:21 GMT

←Older revision		Revision as of 12:31, 3 June 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea==
		+	<StructureSection load='5ajt' size='340' side='right' caption='[[5ajt]], [[Resolution\|resolution]] 2.43Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5ajt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJT FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aju\|5aju]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ajt RCSB], [http://www.ebi.ac.uk/pdbsum/5ajt PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The recently discovered cytokinin-specific phosphoribohydrolase 'Lonely Guy' (LOG) is a key enzyme of cytokinin biosynthesis, converting inactive cytokinin nucleotides into biologically active free-bases. We have determined the crystal structures of LOG from C. purpurea (cpLOG) and its complex with the enzymatic product phosphoribose. The structures reveal a dimeric arrangement of Rossmann folds, with the ligands bound to large pockets at the interface between cpLOG monomers. Structural comparisons highlight the homology of cpLOG to putative lysine decarboxylases. Extended sequence analysis enabled identification of a distinguishing LOG sequence signature. Taken together, our data suggest phosphoribohydrolase activity for several proteins of unknown function. This article is protected by copyright. All rights reserved.

-	The ~~entry 5ajt is ON HOLD until Paper Publication~~	+	The three-dimensional Structure of "Lonely Guy" from Claviceps purpurea provides insights into the phosphoribohydrolase function of Rossmann fold-containing lysine decarboxylase-like proteins.,Dzurova L, Forneris F, Savino S, Galuszka P, Vrabka J, Frebort I Proteins. 2015 May 25. doi: 10.1002/prot.24835. PMID:26010010<ref>PMID:26010010</ref>

-	~~Authors: Dzurova~~, L.~~, Savino,~~ S.~~, Forneris, F~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Dzurova, L]]
	[[Category: Forneris, F]]		[[Category: Forneris, F]]
	[[Category: Savino, S]]		[[Category: Savino, S]]
-	[[Category: ~~Dzurova, L~~]]	+	[[Category: Cytokinin]]
		+	[[Category: Hydrolase]]
		+	[[Category: Lysine decarboxylase]]
		+	[[Category: Rossmann fold]]

OCA: Protected "5ajt" [edit=sysop:move=sysop]

OCA — Wed, 11 Mar 2015 10:59:42 GMT

Protected "5ajt" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:59, 11 March 2015

OCA: New page: '''Unreleased structure''' The entry 5ajt is ON HOLD until Paper Publication Authors: Dzurova, L., Savino, S., Forneris, F. Description: Crystal structure of ligand-free phosphoribohyd...

OCA — Wed, 11 Mar 2015 10:59:41 GMT

New page: '''Unreleased structure''' The entry 5ajt is ON HOLD until Paper Publication Authors: Dzurova, L., Savino, S., Forneris, F. Description: Crystal structure of ligand-free phosphoribohyd...

New page

'''Unreleased structure'''

The entry 5ajt is ON HOLD until Paper Publication

Authors: Dzurova, L., Savino, S., Forneris, F.

Description: Crystal structure of ligand-free phosphoribohydrolase lonely guy from Claviceps purpurea
[[Category: Unreleased Structures]]
[[Category: Forneris, F]]
[[Category: Savino, S]]
[[Category: Dzurova, L]]