5b5i - Revision history

OCA at 06:39, 31 May 2023

OCA — Wed, 31 May 2023 06:39:29 GMT

←Older revision		Revision as of 06:39, 31 May 2023
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	<StructureSection load='5b5i' size='340' side='right'caption='[[5b5i]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='5b5i' size='340' side='right'caption='[[5b5i]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5b5i]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Kuruma_prawn Kuruma prawn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5B5I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5b5i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Penaeus_japonicus Penaeus japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B5I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5i OCA], [~~http~~://pdbe.org/5b5i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5b5i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5b5i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5b5i ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5i OCA], [https://pdbe.org/5b5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b5i RCSB], [https://www.ebi.ac.uk/pdbsum/5b5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b5i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CHH1_PENJP CHH1_PENJP]] Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction.	+	[https://www.uniprot.org/uniprot/CHH1_PENJP CHH1_PENJP] Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Kuruma prawn]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Nagata, K~~]]	+	[[Category: Penaeus japonicus]]
-	[[Category: ~~Tsutsui, N~~]]	+	[[Category: Nagata K]]
-	[[Category: ~~Crustacea]]~~	+	[[Category: Tsutsui N]]
-	~~[[Category: Hormone]]~~	+
-	~~[[Category: Hyperglycemic]]~~	+
-	~~[[Category: Neuropeptide~~]]	+

OCA at 10:05, 26 February 2020

OCA — Wed, 26 Feb 2020 10:05:32 GMT

←Older revision		Revision as of 10:05, 26 February 2020
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	==The crystal structure of a crustacean hyperglycemic hormone precursor from the kuruma prawn==		==The crystal structure of a crustacean hyperglycemic hormone precursor from the kuruma prawn==
-	<StructureSection load='5b5i' size='340' side='right' caption='[[5b5i]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='5b5i' size='340' side='right'caption='[[5b5i]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5b5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B5I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5b5i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kuruma_prawn Kuruma prawn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B5I FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5i OCA], [http://pdbe.org/5b5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b5i RCSB], [http://www.ebi.ac.uk/pdbsum/5b5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b5i ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5i OCA], [http://pdbe.org/5b5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b5i RCSB], [http://www.ebi.ac.uk/pdbsum/5b5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b5i ProSAT]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Kuruma prawn]]
		+	[[Category: Large Structures]]
	[[Category: Nagata, K]]		[[Category: Nagata, K]]
	[[Category: Tsutsui, N]]		[[Category: Tsutsui, N]]

OCA at 11:16, 26 October 2016

OCA — Wed, 26 Oct 2016 11:16:30 GMT

←Older revision		Revision as of 11:16, 26 October 2016
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CHH1_PENJP CHH1_PENJP]] Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction.		[[http://www.uniprot.org/uniprot/CHH1_PENJP CHH1_PENJP]] Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crustacean hyperglycemic hormone (CHH) is one of the major hormones in crustaceans, and peptides belonging to the CHH superfamily have been found in diverse ecdysozoans. Although the basic function of CHH is to control energy metabolism, it also plays various roles in crustacean species, such as in molting and vitellogenesis. Here, we present the crystal structure of Pej-SGP-I-Gly, a partially active precursor of CHH from the kuruma prawn Marsupenaeus japonicus, which has an additional Gly residue in place of the C-terminal amide group of the mature Pej-SGP-I. The 1.6-angstrom crystal structure showed not only the common CHH superfamily scaffold comprising three alpha-helices, three disulfide bridges, and a hydrophobic core, but also revealed that the C-terminal part has a variant backbone fold that is specific to Pej-SGP-I-Gly. The alpha-helix 4 of Pej-SGP-I-Gly was much longer than that of molt-inhibiting hormone (Pej-MIH) from the same species, and as a result, the following C-terminal helix, corresponding to alpha-helix 5 in MIH, was not formed. Unlike monomeric Pej-MIH, Pej-SGP-I-Gly forms a homodimer in the crystal structure via its unique alpha-helix 4. The unexpected dissimilar folds between Pej-SGP-I-Gly and Pej-MIH appear to be the result of their distinct C-terminal amino acid sequences. Variations in amino acid sequences and lengths and the resulting variety of backbone folds allow the C-terminal and sterically adjoining regions to confer different hormonal activities in diverse CHH superfamily members. This article is protected by copyright. All rights reserved.
		+
		+	Crystal structure of a crustacean hyperglycemic hormone (CHH) precursor suggests structural variety in the C-terminal regions of CHH superfamily members.,Tsutsui N, Sakamoto T, Arisaka F, Tanokura M, Nagasawa H, Nagata K FEBS J. 2016 Oct 15. doi: 10.1111/febs.13926. PMID:27743429<ref>PMID:27743429</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5b5i" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 00:55, 20 October 2016

OCA — Thu, 20 Oct 2016 00:55:10 GMT

←Older revision		Revision as of 00:55, 20 October 2016
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-	'''Unreleased structure'''

-	The ~~entry~~ 5b5i is ~~ON HOLD until Paper Publication~~	+	==The crystal structure of a crustacean hyperglycemic hormone precursor from the kuruma prawn==
-		+	<StructureSection load='5b5i' size='340' side='right' caption='[[5b5i]], [[Resolution\|resolution]] 1.60Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5b5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B5I FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5i OCA], [http://pdbe.org/5b5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b5i RCSB], [http://www.ebi.ac.uk/pdbsum/5b5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b5i ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CHH1_PENJP CHH1_PENJP]] Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Nagata, K]]
		+	[[Category: Tsutsui, N]]
		+	[[Category: Crustacea]]
		+	[[Category: Hormone]]
		+	[[Category: Hyperglycemic]]
		+	[[Category: Neuropeptide]]

OCA: Protected "5b5i" [edit=sysop:move=sysop]

OCA — Wed, 01 Jun 2016 09:35:37 GMT

Protected "5b5i" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:35, 1 June 2016

OCA: New page: '''Unreleased structure''' The entry 5b5i is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Wed, 01 Jun 2016 09:35:36 GMT

New page: '''Unreleased structure''' The entry 5b5i is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5b5i is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]