5bob - Revision history

OCA at 06:01, 7 June 2023

OCA — Wed, 07 Jun 2023 06:01:47 GMT

←Older revision		Revision as of 06:01, 7 June 2023
Line 3:		Line 3:
	<StructureSection load='5bob' size='340' side='right'caption='[[5bob]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='5bob' size='340' side='right'caption='[[5bob]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bob]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Strsy Strsy~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5BOB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bob]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_suis_05ZYH33 Streptococcus suis 05ZYH33]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BOB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bob OCA], [https://pdbe.org/5bob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bob RCSB], [https://www.ebi.ac.uk/pdbsum/5bob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bob ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5boa\|5boa]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSU05_0272 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391295 STRSY])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5bob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bob OCA], [~~http~~://pdbe.org/5bob PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5bob RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5bob PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5bob ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A4VT01_STRSY A4VT01_STRSY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strsy~~]]	+	[[Category: Streptococcus suis 05ZYH33]]
-	[[Category: Jiang, Y]]	+	[[Category: Jiang Y]]
-	[[Category: Yu, Y]]	+	[[Category: Yu Y]]
-	[[Category: Zhang, C]]	+	[[Category: Zhang C]]
-	~~[[Category: Beta sandwich core]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 08:51, 11 March 2020

OCA — Wed, 11 Mar 2020 08:51:48 GMT

←Older revision		Revision as of 08:51, 11 March 2020
Line 1:		Line 1:
		+
	==Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb==		==Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb==
-	<StructureSection load='5bob' size='340' side='right' caption='[[5bob]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='5bob' size='340' side='right'caption='[[5bob]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bob]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BOB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bob]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Strsy Strsy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BOB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5boa\|5boa]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5boa\|5boa]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bob OCA], [http://pdbe.org/5bob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bob RCSB], [http://www.ebi.ac.uk/pdbsum/5bob PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSU05_0272 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391295 STRSY])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bob OCA], [http://pdbe.org/5bob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bob RCSB], [http://www.ebi.ac.uk/pdbsum/5bob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bob ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Strsy]]
	[[Category: Jiang, Y]]		[[Category: Jiang, Y]]
	[[Category: Yu, Y]]		[[Category: Yu, Y]]

OCA at 18:58, 1 December 2015

OCA — Tue, 01 Dec 2015 18:58:54 GMT

←Older revision		Revision as of 18:58, 1 December 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb==
		+	<StructureSection load='5bob' size='340' side='right' caption='[[5bob]], [[Resolution\|resolution]] 1.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5bob]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BOB FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5boa\|5boa]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bob OCA], [http://pdbe.org/5bob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bob RCSB], [http://www.ebi.ac.uk/pdbsum/5bob PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fhb is a surface virulence protein from Streptococcus suis, which could aid bacterial evasion of host innate immune defense by recruiting complement regulator factor H to inactivate C3b deposited on bacterial surface in blood. Here we successfully expressed and purified the N terminal domain of Fhb (N-Fhb) and obtained crystals of the N-Fhb by sitting-drop vapor diffusion method with a resolution of 1.50 A. The crystals belong to space group C2 with unit cell parameters a = 127.1 A, b = 77.3 A, c = 131.6 A, alpha = 90 degrees , beta = 115.9 degrees , gamma = 90 degrees . The structure of N-Fhb was determined by SAD method and the core structure of N-Fhb is a beta sandwich. We speculated that binding of Fhb to human factor H may be mainly mediated by surface amino acids with negative charges.

-	~~The entry 5bob is ON HOLD until Paper Publication~~	+	Expression, purification, crystallization and structure determination of the N terminal domain of Fhb, a factor H binding protein from Streptococcus suis.,Zhang C, Yu Y, Yang M, Jiang Y Biochem Biophys Res Commun. 2015 Oct 23;466(3):413-7. doi:, 10.1016/j.bbrc.2015.09.040. Epub 2015 Sep 10. PMID:26365348<ref>PMID:26365348</ref>

-	~~Authors: Jiang~~, Y.~~, Zhang, C~~.~~, Yu, Y~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb~~	+	<div class="pdbe-citations 5bob" style="background-color:#fffaf0;"></div>
-	~~[[Category: Unreleased Structures]]~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Jiang, Y]]		[[Category: Jiang, Y]]
	[[Category: Yu, Y]]		[[Category: Yu, Y]]
	[[Category: Zhang, C]]		[[Category: Zhang, C]]
		+	[[Category: Beta sandwich core]]
		+	[[Category: Translation]]

OCA at 08:36, 9 September 2015

OCA — Wed, 09 Sep 2015 08:36:43 GMT

←Older revision		Revision as of 08:36, 9 September 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5bob is ON HOLD	+	The entry 5bob is ON HOLD until Paper Publication

	Authors: Jiang, Y., Zhang, C., Yu, Y.		Authors: Jiang, Y., Zhang, C., Yu, Y.

OCA at 12:49, 10 June 2015

OCA — Wed, 10 Jun 2015 12:49:17 GMT

←Older revision		Revision as of 12:49, 10 June 2015
Line 3:		Line 3:
	The entry 5bob is ON HOLD		The entry 5bob is ON HOLD

-	Authors: Y.J., C.Z., ~~Y.Y.~~, M.Y.	+	Authors: Jiang, Y., Zhang, C., Yu, Y.

	Description: Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb		Description: Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~C.Z]]~~	+	[[Category: Jiang, Y]]
-	~~[[Category:~~ Y.J]]	+	[[Category: Yu, Y]]
-	[[Category: Y.Y]]	+	[[Category: Zhang, C]]
-	[[Category: ~~M.Y~~]]	+

OCA: Protected "5bob" [edit=sysop:move=sysop]

OCA — Wed, 03 Jun 2015 11:42:37 GMT

Protected "5bob" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:42, 3 June 2015

OCA: New page: '''Unreleased structure''' The entry 5bob is ON HOLD Authors: Y.J., C.Z., Y.Y., M.Y. Description: Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb [[Categor...

OCA — Wed, 03 Jun 2015 11:42:36 GMT

New page: '''Unreleased structure''' The entry 5bob is ON HOLD Authors: Y.J., C.Z., Y.Y., M.Y. Description: Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb [[Categor...

New page

'''Unreleased structure'''

The entry 5bob is ON HOLD

Authors: Y.J., C.Z., Y.Y., M.Y.

Description: Crystal Structure of the Meningitis Pathogen Streptococcus suis adhesion Fhb
[[Category: Unreleased Structures]]
[[Category: C.Z]]
[[Category: Y.J]]
[[Category: Y.Y]]
[[Category: M.Y]]