5bz2 - Revision history

OCA at 11:17, 10 January 2024

OCA — Wed, 10 Jan 2024 11:17:38 GMT

←Older revision		Revision as of 11:17, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [https://pdbe.org/5bz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bz2 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.7Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [https://pdbe.org/5bz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bz2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:13, 7 June 2023

OCA — Wed, 07 Jun 2023 06:13:16 GMT

←Older revision		Revision as of 06:13, 7 June 2023
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	<StructureSection load='5bz2' size='340' side='right'caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>		<StructureSection load='5bz2' size='340' side='right'caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TT_C1108 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [https://pdbe.org/5bz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bz2 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [~~http~~://pdbe.org/5bz2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5bz2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5bz2 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5SIA2_THET8 Q5SIA2_THET8]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cameron, A]]	+	[[Category: Thermus thermophilus]]
-	[[Category: Coincon, M]]	+	[[Category: Cameron A]]
-	[[Category: Drew, D]]	+	[[Category: Coincon M]]
-	[[Category: Uzdavinys, P]]	+	[[Category: Drew D]]
-	~~[[Category: Cystein crosslink]]~~	+	[[Category: Uzdavinys P]]
-	~~[[Category: Inward-facing]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 11:04, 18 March 2020

OCA — Wed, 18 Mar 2020 11:04:45 GMT

←Older revision		Revision as of 11:04, 18 March 2020
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	==CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION==		==CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION==
-	<StructureSection load='5bz2' size='340' side='right' caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>	+	<StructureSection load='5bz2' size='340' side='right'caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [http://pdbe.org/5bz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bz2 PDBsum]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TT_C1108 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 "Flavobacterium thermophilum" Yoshida and Oshima 1971])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [http://pdbe.org/5bz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bz2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
		+	[[Category: Large Structures]]
	[[Category: Cameron, A]]		[[Category: Cameron, A]]
	[[Category: Coincon, M]]		[[Category: Coincon, M]]

OCA at 19:44, 9 March 2016

OCA — Wed, 09 Mar 2016 19:44:07 GMT

←Older revision		Revision as of 19:44, 9 March 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION==		==CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION==
	<StructureSection load='5bz2' size='340' side='right' caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>		<StructureSection load='5bz2' size='340' side='right' caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>

OCA at 08:58, 10 February 2016

OCA — Wed, 10 Feb 2016 08:58:38 GMT

←Older revision		Revision as of 08:58, 10 February 2016
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	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [http://pdbe.org/5bz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bz2 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [http://pdbe.org/5bz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bz2 PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To fully understand the transport mechanism of Na+/H+ exchangers, it is necessary to clearly establish the global rearrangements required to facilitate ion translocation. Currently, two different transport models have been proposed. Some reports have suggested that structural isomerization is achieved through large elevator-like rearrangements similar to those seen in the structurally unrelated sodium-coupled glutamate-transporter homolog GltPh. Others have proposed that only small domain movements are required for ion exchange, and a conventional rocking-bundle model has been proposed instead. Here, to resolve these differences, we report atomic-resolution structures of the same Na+/H+ antiporter (NapA from Thermus thermophilus) in both outward- and inward-facing conformations. These data combined with cross-linking, molecular dynamics simulations and isothermal calorimetry suggest that Na+/H+ antiporters provide alternating access to the ion-binding site by using elevator-like structural transitions.
		+
		+	Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.,Coincon M, Uzdavinys P, Nji E, Dotson DL, Winkelmann I, Abdul-Hussein S, Cameron AD, Beckstein O, Drew D Nat Struct Mol Biol. 2016 Feb 1. doi: 10.1038/nsmb.3164. PMID:26828964<ref>PMID:26828964</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5bz2" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:16, 20 January 2016

OCA — Wed, 20 Jan 2016 17:16:57 GMT

←Older revision		Revision as of 17:16, 20 January 2016
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-	'''~~Unreleased structure~~'''	+	==CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION==
-		+	<StructureSection load='5bz2' size='340' side='right' caption='[[5bz2]], [[Resolution\|resolution]] 3.70Å' scene=''>
-	~~The entry~~ 5bz2 is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5bz2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZ2 FirstGlance]. <br>
-	~~Authors~~: ~~Coincon, M~~.~~, Uzdavinys, P~~.~~, Cameron, A~~.~~, Drew, D~~.	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bz2 OCA], [http://pdbe.org/5bz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bz2 PDBsum]</span></td></tr>
-		+	</table>
-	~~Description~~: ~~CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER~~, ~~NAPA~~	+	__TOC__
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</StructureSection>
	[[Category: Cameron, A]]		[[Category: Cameron, A]]
	[[Category: Coincon, M]]		[[Category: Coincon, M]]
-	[[Category: Uzdavinys, P]]
	[[Category: Drew, D]]		[[Category: Drew, D]]
		+	[[Category: Uzdavinys, P]]
		+	[[Category: Cystein crosslink]]
		+	[[Category: Inward-facing]]
		+	[[Category: Transport protein]]

OCA: Protected "5bz2" [edit=sysop:move=sysop]

OCA — Wed, 17 Jun 2015 14:05:59 GMT

Protected "5bz2" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:05, 17 June 2015

OCA: New page: '''Unreleased structure''' The entry 5bz2 is ON HOLD Authors: Coincon, M., Uzdavinys, P., Cameron, A., Drew, D. Description: CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER, NAPA [[C...

OCA — Wed, 17 Jun 2015 14:05:58 GMT

New page: '''Unreleased structure''' The entry 5bz2 is ON HOLD Authors: Coincon, M., Uzdavinys, P., Cameron, A., Drew, D. Description: CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER, NAPA [[C...

New page

'''Unreleased structure'''

The entry 5bz2 is ON HOLD

Authors: Coincon, M., Uzdavinys, P., Cameron, A., Drew, D.

Description: CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER, NAPA
[[Category: Unreleased Structures]]
[[Category: Cameron, A]]
[[Category: Coincon, M]]
[[Category: Uzdavinys, P]]
[[Category: Drew, D]]