5c7o - Revision history

OCA at 08:35, 27 September 2023

OCA — Wed, 27 Sep 2023 08:35:32 GMT

←Older revision		Revision as of 08:35, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C7O FirstGlance]. <br>		<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C7O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.729Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [https://pdbe.org/5c7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [https://www.ebi.ac.uk/pdbsum/5c7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [https://pdbe.org/5c7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [https://www.ebi.ac.uk/pdbsum/5c7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7o ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:23, 7 June 2023

OCA — Wed, 07 Jun 2023 06:23:11 GMT

←Older revision		Revision as of 06:23, 7 June 2023
Line 3:		Line 3:
	<StructureSection load='5c7o' size='340' side='right'caption='[[5c7o]], [[Resolution\|resolution]] 1.73Å' scene=''>		<StructureSection load='5c7o' size='340' side='right'caption='[[5c7o]], [[Resolution\|resolution]] 1.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5C7O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C7O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=~~SO4~~:~~SULFATE~~+~~ION~~'>~~SO4~~</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~OCS~~:~~CYSTEINESULFONIC~~+~~ACID~~'>~~OCS~~</scene~~></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [https://pdbe.org/5c7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [https://www.ebi.ac.uk/pdbsum/5c7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7o ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5c7l\|5c7l]]</td></tr>~~	+
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAPDHS, GAPD2, GAPDH2, GAPDS, HSD-35, HSD35 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [~~http~~://pdbe.org/5c7o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5c7o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7o ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/G3PT_HUMAN G3PT_HUMAN]] May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).	+	[https://www.uniprot.org/uniprot/G3PT_HUMAN G3PT_HUMAN] May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 29:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Betts, L]]	+	[[Category: Betts L]]
-	~~[[Category: Brien, D O~~]]	+	[[Category: Danshina P]]
-	[[Category: Danshina, P]]	+	[[Category: Machius M]]
-	[[Category: Machius, M]]	+	[[Category: O'Brien D]]
-	[[Category: ~~Human sperm gapdh metabolic enzyme sperm specific with nad+ cofactor]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 11:15, 18 March 2020

OCA — Wed, 18 Mar 2020 11:15:01 GMT

←Older revision		Revision as of 11:15, 18 March 2020
Line 1:		Line 1:

	==Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+==		==Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+==
-	<StructureSection load='5c7o' size='340' side='right' caption='[[5c7o]], [[Resolution\|resolution]] 1.73Å' scene=''>	+	<StructureSection load='5c7o' size='340' side='right'caption='[[5c7o]], [[Resolution\|resolution]] 1.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7O FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5c7l\|5c7l]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5c7l\|5c7l]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GAPDHS, GAPD2, GAPDH2, GAPDS, HSD-35, HSD35 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [http://pdbe.org/5c7o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [http://www.ebi.ac.uk/pdbsum/5c7o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [http://pdbe.org/5c7o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [http://www.ebi.ac.uk/pdbsum/5c7o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 22:
	</div>		</div>
	<div class="pdbe-citations 5c7o" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5c7o" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures\|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Betts, L]]		[[Category: Betts, L]]
	[[Category: Brien, D O]]		[[Category: Brien, D O]]

OCA at 03:35, 10 March 2016

OCA — Thu, 10 Mar 2016 03:35:43 GMT

←Older revision		Revision as of 03:35, 10 March 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5c7o is ~~ON HOLD until Paper~~ Publication	+	==Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+==
		+	<StructureSection load='5c7o' size='340' side='right' caption='[[5c7o]], [[Resolution\|resolution]] 1.73Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5c7o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7O FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5c7l\|5c7l]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7o OCA], [http://pdbe.org/5c7o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c7o RCSB], [http://www.ebi.ac.uk/pdbsum/5c7o PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/G3PT_HUMAN G3PT_HUMAN]] May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	STUDY HYPOTHESIS: Detailed structural comparisons of sperm-specific glyceraldehyde 3-phosphate dehydrogenase, spermatogenic (GAPDHS) and the somatic glyceraldehyde 3-phosphate dehydrogenase (GAPDH) isozyme should facilitate the identification of selective GAPDHS inhibitors for contraceptive development. STUDY FINDING: This study identified a small-molecule GAPDHS inhibitor with micromolar potency and >10-fold selectivity that exerts the expected inhibitory effects on sperm glycolysis and motility. WHAT IS KNOWN ALREADY: Glycolytic ATP production is required for sperm motility and male fertility in many mammalian species. Selective inhibition of GAPDHS, one of the glycolytic isozymes with restricted expression during spermatogenesis, is a potential strategy for the development of a non-hormonal contraceptive that directly blocks sperm function. STUDY DESIGN, SAMPLES/MATERIALS, METHODS: Homology modeling and x-ray crystallography were used to identify structural features that are conserved in GAPDHS orthologs in mouse and human sperm, but distinct from the GAPDH orthologs present in somatic tissues. We identified three binding pockets surrounding the substrate and cofactor in these isozymes and conducted a virtual screen to identify small-molecule compounds predicted to bind more tightly to GAPDHS than to GAPDH. Following the production of recombinant human and mouse GAPDHS, candidate compounds were tested in dose-response enzyme assays to identify inhibitors that blocked the activity of GAPDHS more effectively than GAPDH. The effects of a selective inhibitor on the motility of mouse and human sperm were monitored by computer-assisted sperm analysis, and sperm lactate production was measured to assess inhibition of glycolysis in the target cell. MAIN RESULTS AND THE ROLE OF CHANCE: Our studies produced the first apoenzyme crystal structures for human and mouse GAPDHS and a 1.73 A crystal structure for NAD+-bound human GAPDHS, facilitating the identification of unique structural features of this sperm isozyme. In dose-response assays T0501_7749 inhibited human GAPDHS with an IC50 of 1.2 microM compared to an IC50 of 38.5 microM for the somatic isozyme. This compound caused significant reductions in mouse sperm lactate production (P=0.017 for 100 microM T0501_7749 versus control) and in the percentage of motile mouse and human sperm (P values from<0.05 to<0.0001, depending on incubation conditions). LIMITATIONS, REASONS FOR CAUTION: The chemical properties of T0501_7749, including limited solubility and nonspecific protein binding, are not optimal for drug development. WIDER IMPLICATIONS OF THE FINDINGS: This study provides proof-of-principle evidence that GAPDHS can be selectively inhibited, causing significant reductions in sperm glycolysis and motility. These results highlight the utility of structure-based drug design and support further exploration of GAPDHS, and perhaps other sperm-specific isozymes in the glycolytic pathway, as contraceptive targets. LARGE SCALE DATA: None. Coordinates and data files for three GAPDHS crystal structures were deposited in the RCSB Protein Data Bank (http://www.rcsb.org). STUDY FUNDING AND COMPETING INTERESTS: This work was supported by grants from the National Institutes of Health (NIH), USA, including U01 HD060481 and cooperative agreement U54 HD35041 as part of the Specialized Cooperative Centers Program in Reproduction and Infertility Research from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and TW/HD00627 from the NIH Fogarty International Center. Additional support was provided by subproject CIG-05-109 from CICCR, a program of CONRAD, Eastern Virginia Medical School, USA. There are no conflicts of interest.

-	~~Authors: Betts~~, L., ~~Machius~~, M., ~~Danshina~~, P., O'Brien~~, D~~.	+	Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.,Danshina PV, Qu W, Temple BR, Rojas RJ, Miley MJ, Machius M, Betts L, O'Brien DA Mol Hum Reprod. 2016 Feb 26. pii: gaw016. PMID:26921398<ref>PMID:26921398</ref>

-	~~Description: Structure~~ of ~~human testis~~-~~specific glyceraldehyde~~-~~3-phosphate dehydrogenase holo form with NAD+~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	~~[[Category: O'Brien, D]]~~	+	<div class="pdbe-citations 5c7o" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Betts, L]]		[[Category: Betts, L]]
		+	[[Category: Brien, D O]]
	[[Category: Danshina, P]]		[[Category: Danshina, P]]
	[[Category: Machius, M]]		[[Category: Machius, M]]
		+	[[Category: Human sperm gapdh metabolic enzyme sperm specific with nad+ cofactor]]
		+	[[Category: Oxidoreductase]]

OCA at 12:54, 12 August 2015

OCA — Wed, 12 Aug 2015 12:54:01 GMT

←Older revision		Revision as of 12:54, 12 August 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5c7o is ON HOLD	+	The entry 5c7o is ON HOLD until Paper Publication

	Authors: Betts, L., Machius, M., Danshina, P., O'Brien, D.		Authors: Betts, L., Machius, M., Danshina, P., O'Brien, D.

OCA at 13:47, 8 July 2015

OCA — Wed, 08 Jul 2015 13:47:59 GMT

←Older revision		Revision as of 13:47, 8 July 2015
Line 3:		Line 3:
	The entry 5c7o is ON HOLD		The entry 5c7o is ON HOLD

-	Authors: Betts, L., Machius, M, Danshina, P, O'Brien D	+	Authors: Betts, L., Machius, M., Danshina, P., O'Brien, D.

	Description: Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+		Description: Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: O'Brien, D]]
	[[Category: Betts, L]]		[[Category: Betts, L]]
-	[[Category: ~~Machius, M,~~ Danshina, P, ~~O'Brien D~~]]	+	[[Category: Danshina, P]]
		+	[[Category: Machius, M]]

OCA: Protected "5c7o" [edit=sysop:move=sysop]

OCA — Wed, 01 Jul 2015 11:15:39 GMT

Protected "5c7o" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:15, 1 July 2015

OCA: New page: '''Unreleased structure''' The entry 5c7o is ON HOLD Authors: Betts, L., Machius, M, Danshina, P, O'Brien D Description: Structure of human testis-specific glyceraldehyde-3-phosphate d...

OCA — Wed, 01 Jul 2015 11:15:38 GMT

New page: '''Unreleased structure''' The entry 5c7o is ON HOLD Authors: Betts, L., Machius, M, Danshina, P, O'Brien D Description: Structure of human testis-specific glyceraldehyde-3-phosphate d...

New page

'''Unreleased structure'''

The entry 5c7o is ON HOLD

Authors: Betts, L., Machius, M, Danshina, P, O'Brien D

Description: Structure of human testis-specific glyceraldehyde-3-phosphate dehydrogenase holo form with NAD+
[[Category: Unreleased Structures]]
[[Category: Betts, L]]
[[Category: Machius, M, Danshina, P, O'Brien D]]