5c7w - Revision history

OCA at 07:21, 1 May 2024

OCA — Wed, 01 May 2024 07:21:52 GMT

←Older revision		Revision as of 07:21, 1 May 2024
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [https://pdbe.org/5c7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [https://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [https://pdbe.org/5c7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [https://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	As one of its goals, synthetic biology seeks to increase the number of building blocks in nucleic acids. While efforts towards this goal are well advanced for DNA, they have hardly begun for RNA. Herein, we present a crystal structure for an RNA riboswitch where a stem C:G pair has been replaced by a pair between two components of an artificially expanded genetic-information system (AEGIS), Z and P, (6-amino-5-nitro-2(1H)-pyridone and 2-amino-imidazo[1,2-a]-1,3,5-triazin-4-(8H)-one). The structure shows that the Z:P pair does not greatly change the conformation of the RNA molecule nor the details of its interaction with a hypoxanthine ligand. This was confirmed in solution by in-line probing, which also measured a 3.7 nM affinity of the riboswitch for guanine. These data show that the Z:P pair mimics the natural Watson-Crick geometry in RNA in the first example of a crystal structure of an RNA molecule that contains an orthogonal added nucleobase pair.
-
-	A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.,Hernandez AR, Shao Y, Hoshika S, Yang Z, Shelke SA, Herrou J, Kim HJ, Kim MJ, Piccirilli JA, Benner SA Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9853-6. doi: 10.1002/anie.201504731., Epub 2015 Jul 16. PMID:26223188<ref>PMID:26223188</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5c7w" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Riboswitch 3D structures\|Riboswitch 3D structures]]		*[[Riboswitch 3D structures\|Riboswitch 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:35, 27 September 2023

OCA — Wed, 27 Sep 2023 08:35:43 GMT

←Older revision		Revision as of 08:35, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C7W FirstGlance]. <br>		<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C7W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.22Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [https://pdbe.org/5c7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [https://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [https://pdbe.org/5c7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [https://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:23, 7 June 2023

OCA — Wed, 07 Jun 2023 06:23:26 GMT

←Older revision		Revision as of 06:23, 7 June 2023
Line 3:		Line 3:
	<StructureSection load='5c7w' size='340' side='right'caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>		<StructureSection load='5c7w' size='340' side='right'caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5C7W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C7W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene>, <scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
-	~~<tr~~ id~~='NonStdRes'><td class~~="~~sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat~~"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [https://pdbe.org/5c7w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [https://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [~~http~~://pdbe.org/5c7w PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Benner~~, S A~~]]	+	[[Category: Synthetic construct]]
-	[[Category: Hernandez~~, A R~~]]	+	[[Category: Benner SA]]
-	[[Category: Herrou, J]]	+	[[Category: Hernandez AR]]
-	[[Category: Hoshika, S]]	+	[[Category: Herrou J]]
-	[[Category: Kim, H J]]	+	[[Category: Hoshika S]]
-	[[Category: Kim, M J]]	+	[[Category: Kim H-J]]
-	[[Category: Piccirilli~~, J A~~]]	+	[[Category: Kim M-J]]
-	[[Category: Shao, Y]]	+	[[Category: Piccirilli JA]]
-	[[Category: Shelke~~, S A~~]]	+	[[Category: Shao Y]]
-	[[Category: Yang, Z]]	+	[[Category: Shelke SA]]
-	~~[[Category: Expanded rna]]~~	+	[[Category: Yang Z]]
-	~~[[Category: Riboswitch]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Unnatural base pair~~]]	+

OCA at 08:52, 1 January 2020

OCA — Wed, 01 Jan 2020 08:52:56 GMT

←Older revision		Revision as of 08:52, 1 January 2020
Line 1:		Line 1:

	==5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.==		==5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.==
-	<StructureSection load='5c7w' size='340' side='right' caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>	+	<StructureSection load='5c7w' size='340' side='right'caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7W FirstGlance]. <br>		<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7W FirstGlance]. <br>
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[Riboswitch\|Riboswitch]]	+	*[[Riboswitch 3D structures\|Riboswitch 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Benner, S A]]		[[Category: Benner, S A]]
	[[Category: Hernandez, A R]]		[[Category: Hernandez, A R]]

OCA at 09:49, 22 November 2017

OCA — Wed, 22 Nov 2017 09:49:01 GMT

←Older revision		Revision as of 09:49, 22 November 2017
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 5c7w" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5c7w" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Riboswitch\|Riboswitch]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:12, 24 May 2017

OCA — Wed, 24 May 2017 14:12:03 GMT

←Older revision		Revision as of 14:12, 24 May 2017
Line 1:		Line 1:
		+
	==5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.==		==5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.==
	<StructureSection load='5c7w' size='340' side='right' caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>		<StructureSection load='5c7w' size='340' side='right' caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [http://www.ebi.ac.uk/pdbsum/5c7w PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [http://pdbe.org/5c7w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [http://www.ebi.ac.uk/pdbsum/5c7w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c7w ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 5c7w" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:33, 12 August 2015

OCA — Wed, 12 Aug 2015 14:33:22 GMT

←Older revision		Revision as of 14:33, 12 August 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.==
		+	<StructureSection load='5c7w' size='340' side='right' caption='[[5c7w]], [[Resolution\|resolution]] 3.22Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5c7w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7W FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=50L:[(2R,3S,4R,5R)-5-(4-AZANYL-2-OXIDANYLIDENE-1$L^{4},3,5,7-TETRAZABICYCLO[4.3.0]NONA-1(6),3,8-TRIEN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>50L</scene>, <scene name='pdbligand=50N:(1S)-1-(6-AMINO-2-HYDROXY-5-NITROPYRIDIN-3-YL)-1,4-ANHYDRO-5-O-PHOSPHONO-D-RIBITOL'>50N</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c7w RCSB], [http://www.ebi.ac.uk/pdbsum/5c7w PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	As one of its goals, synthetic biology seeks to increase the number of building blocks in nucleic acids. While efforts towards this goal are well advanced for DNA, they have hardly begun for RNA. Herein, we present a crystal structure for an RNA riboswitch where a stem C:G pair has been replaced by a pair between two components of an artificially expanded genetic-information system (AEGIS), Z and P, (6-amino-5-nitro-2(1H)-pyridone and 2-amino-imidazo[1,2-a]-1,3,5-triazin-4-(8H)-one). The structure shows that the Z:P pair does not greatly change the conformation of the RNA molecule nor the details of its interaction with a hypoxanthine ligand. This was confirmed in solution by in-line probing, which also measured a 3.7 nM affinity of the riboswitch for guanine. These data show that the Z:P pair mimics the natural Watson-Crick geometry in RNA in the first example of a crystal structure of an RNA molecule that contains an orthogonal added nucleobase pair.

-	~~The entry 5c7w is ON HOLD until Paper Publication~~	+	A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.,Hernandez AR, Shao Y, Hoshika S, Yang Z, Shelke SA, Herrou J, Kim HJ, Kim MJ, Piccirilli JA, Benner SA Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9853-6. doi: 10.1002/anie.201504731., Epub 2015 Jul 16. PMID:26223188<ref>PMID:26223188</ref>

-	~~Authors: Hernandez~~, A.~~R., Shao, Y., Hoshika,~~ S.~~, Yang, Z~~.~~, Shelke~~, S.A., Herrou, J., Kim, H.-J., Kim, M.-J., Piccirilli, J.A~~., Benner, S.A.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Benner, S A]]
		+	[[Category: Hernandez, A R]]
		+	[[Category: Herrou, J]]
		+	[[Category: Hoshika, S]]
		+	[[Category: Kim, H J]]
		+	[[Category: Kim, M J]]
		+	[[Category: Piccirilli, J A]]
		+	[[Category: Shao, Y]]
		+	[[Category: Shelke, S A]]
	[[Category: Yang, Z]]		[[Category: Yang, Z]]
-	[[Category: ~~Shao, Y~~]]	+	[[Category: Expanded rna]]
-	[[Category: ~~Piccirilli, J.A~~]]	+	[[Category: Riboswitch]]
-	[[Category: ~~Hoshika, S~~]]	+	[[Category: Rna]]
-	[[Category: ~~Kim, M.-J]]~~	+	[[Category: Unnatural base pair]]
-	~~[[Category: Shelke, S.A]]~~	+
-	~~[[Category: Herrou, J]]~~	+
-	~~[[Category: Kim, H.-J]]~~	+
-	~~[[Category: Benner, S.A]]~~	+
-	~~[[Category: Hernandez, A.R~~]]	+

OCA at 13:09, 29 July 2015

OCA — Wed, 29 Jul 2015 13:09:08 GMT

←Older revision		Revision as of 13:09, 29 July 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5c7w is ON HOLD	+	The entry 5c7w is ON HOLD until Paper Publication

	Authors: Hernandez, A.R., Shao, Y., Hoshika, S., Yang, Z., Shelke, S.A., Herrou, J., Kim, H.-J., Kim, M.-J., Piccirilli, J.A., Benner, S.A.		Authors: Hernandez, A.R., Shao, Y., Hoshika, S., Yang, Z., Shelke, S.A., Herrou, J., Kim, H.-J., Kim, M.-J., Piccirilli, J.A., Benner, S.A.

OCA at 12:15, 15 July 2015

OCA — Wed, 15 Jul 2015 12:15:13 GMT

←Older revision		Revision as of 12:15, 15 July 2015
Line 3:		Line 3:
	The entry 5c7w is ON HOLD		The entry 5c7w is ON HOLD

-	Authors: Hernandez, A.R., Shao, Y., Hoshika, S., Yang, Z., Shelke, S.A., Herrou, J., Kim, H-J., Kim, M-J., Piccirilli, J.A., Benner, S.A.	+	Authors: Hernandez, A.R., Shao, Y., Hoshika, S., Yang, Z., Shelke, S.A., Herrou, J., Kim, H.-J., Kim, M.-J., Piccirilli, J.A., Benner, S.A.

	Description: 5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.		Description: 5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.
Line 11:		Line 11:
	[[Category: Piccirilli, J.A]]		[[Category: Piccirilli, J.A]]
	[[Category: Hoshika, S]]		[[Category: Hoshika, S]]
		+	[[Category: Kim, M.-J]]
	[[Category: Shelke, S.A]]		[[Category: Shelke, S.A]]
-	[[Category: Kim, H-J]]
	[[Category: Herrou, J]]		[[Category: Herrou, J]]
		+	[[Category: Kim, H.-J]]
	[[Category: Benner, S.A]]		[[Category: Benner, S.A]]
-	[[Category: Kim, M-J]]
	[[Category: Hernandez, A.R]]		[[Category: Hernandez, A.R]]

OCA: Protected "5c7w" [edit=sysop:move=sysop]

OCA — Wed, 01 Jul 2015 11:16:48 GMT

Protected "5c7w" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:16, 1 July 2015