5c9y - Revision history

OCA at 11:19, 10 January 2024

OCA — Wed, 10 Jan 2024 11:19:23 GMT

←Older revision		Revision as of 11:19, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lupinus_luteus Lupinus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lupinus_luteus Lupinus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [https://pdbe.org/5c9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [https://www.ebi.ac.uk/pdbsum/5c9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9y ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [https://pdbe.org/5c9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [https://www.ebi.ac.uk/pdbsum/5c9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:25, 7 June 2023

OCA — Wed, 07 Jun 2023 06:25:56 GMT

←Older revision		Revision as of 06:25, 7 June 2023
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	<StructureSection load='5c9y' size='340' side='right'caption='[[5c9y]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='5c9y' size='340' side='right'caption='[[5c9y]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~European_yellow_lupine European yellow lupine~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lupinus_luteus Lupinus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LLR18A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3873 European yellow lupine])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [https://pdbe.org/5c9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [https://www.ebi.ac.uk/pdbsum/5c9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9y ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [~~http~~://pdbe.org/5c9y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5c9y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9y ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/L18A_LUPLU L18A_LUPLU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: European yellow lupine]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Jaskolski, M~~]]	+	[[Category: Lupinus luteus]]
-	[[Category: ~~Sikorski, M~~ M]]	+	[[Category: Jaskolski M]]
-	[[Category: ~~Sliwiak, J~~]]	+	[[Category: Sikorski MM]]
-	[[Category: ~~Cytokinin]]~~	+	[[Category: Sliwiak J]]
-	~~[[Category: Ligand binding]]~~	+
-	~~[[Category: Phytohormone binding protein]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Pr-10 fold]]~~	+
-	~~[[Category: Trans-zeatin~~]]	+

OCA at 12:22, 17 July 2019

OCA — Wed, 17 Jul 2019 12:22:26 GMT

←Older revision		Revision as of 12:22, 17 July 2019
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		+
	==Crystal structure of yellow lupine LlPR-10.1A protein partially saturated with trans-zeatin==		==Crystal structure of yellow lupine LlPR-10.1A protein partially saturated with trans-zeatin==
-	<StructureSection load='5c9y' size='340' side='right' caption='[[5c9y]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='5c9y' size='340' side='right'caption='[[5c9y]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_yellow_lupine European yellow lupine]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [http://pdbe.org/5c9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [http://www.ebi.ac.uk/pdbsum/5c9y PDBsum]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LLR18A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3873 European yellow lupine])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [http://pdbe.org/5c9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [http://www.ebi.ac.uk/pdbsum/5c9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9y ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: European yellow lupine]]
		+	[[Category: Large Structures]]
	[[Category: Jaskolski, M]]		[[Category: Jaskolski, M]]
	[[Category: Sikorski, M M]]		[[Category: Sikorski, M M]]

OCA at 06:22, 23 December 2015

OCA — Wed, 23 Dec 2015 06:22:32 GMT

←Older revision		Revision as of 06:22, 23 December 2015
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	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [http://pdbe.org/5c9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [http://www.ebi.ac.uk/pdbsum/5c9y PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [http://pdbe.org/5c9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [http://www.ebi.ac.uk/pdbsum/5c9y PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Plant pathogenesis-related class 10 (PR-10) proteins are a family of abundant proteins initially identified as elements of the plant defense system. The key structural feature suggesting PR-10 functionality is a huge hydrophobic cavity created in the protein interior by a scaffold composed of an extended beta-sheet wrapped around a long and flexible C-terminal alpha-helix. Several crystallographic and NMR studies have shown that the cavity can accommodate a variety of small molecule ligands, including phytohormones. The article describes approximately 1.3A resolution crystal structures of a Lupinus luteus PR-10 isoform LlPR-10.1A, in its free form and in complex with trans-zeatin, a naturally occurring plant hormone belonging to the cytokinin group. Moreover we present the structure of the same protein where the saturation with zeatin is not complete. This set of three crystal structures allows us to track the structural adaptation of the protein upon trans-zeatin docking, as well as the sequence of the ligand-binding events, step-by-step. In addition, titration of LlPR-10.1A with trans-zeatin monitored in solution by CD spectra, confirmed the pattern of structural adaptations deduced from the crystallographic studies. The ligand-biding mode shows no similarity to other zeatin complexes of PR-10 proteins. The present work, which describes the first atomic models of the same PR-10 protein with and without a physiological ligand, reveals that the conformation of LlPR-10.1A undergoes a significant structural rearrangement upon trans-zeatin binding.
		+
		+	Crystallographic and CD probing of ligand-induced conformational changes in a plant PR-10 protein.,Sliwiak J, Dolot R, Michalska K, Szpotkowski K, Bujacz G, Sikorski M, Jaskolski M J Struct Biol. 2015 Nov 28. pii: S1047-8477(15)30105-2. doi:, 10.1016/j.jsb.2015.11.008. PMID:26644353<ref>PMID:26644353</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5c9y" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:48, 9 December 2015

OCA — Wed, 09 Dec 2015 13:48:28 GMT

←Older revision		Revision as of 13:48, 9 December 2015
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	==Crystal structure of yellow lupine LlPR-10.1A protein partially saturated with trans-zeatin==
-		+	<StructureSection load='5c9y' size='340' side='right' caption='[[5c9y]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~The entry 5c9y is ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5c9y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C9Y FirstGlance]. <br>
-	~~Authors: Sliwiak, J., Sikorski, M.M., Jaskolski, M.~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9y OCA], [http://pdbe.org/5c9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c9y RCSB], [http://www.ebi.ac.uk/pdbsum/5c9y PDBsum]</span></td></tr>
-		+	</table>
-	~~Description: Structure~~ of ~~LLPR~~-10.1A protein partially saturated with trans-zeatin.	+	__TOC__
-	[[~~Category: Unreleased Structures~~]]	+	</StructureSection>
-	[[~~Category~~: ~~Sliwiak, J~~]]	+
-	[[~~Category~~: ~~Sikorski~~, M.M]]	+
	[[Category: Jaskolski, M]]		[[Category: Jaskolski, M]]
		+	[[Category: Sikorski, M M]]
		+	[[Category: Sliwiak, J]]
		+	[[Category: Cytokinin]]
		+	[[Category: Ligand binding]]
		+	[[Category: Phytohormone binding protein]]
		+	[[Category: Plant protein]]
		+	[[Category: Pr-10 fold]]
		+	[[Category: Trans-zeatin]]

OCA at 10:34, 20 August 2015

OCA — Thu, 20 Aug 2015 10:34:20 GMT

←Older revision		Revision as of 10:34, 20 August 2015
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5c9y is ON HOLD	+	The entry 5c9y is ON HOLD until Paper Publication

	Authors: Sliwiak, J., Sikorski, M.M., Jaskolski, M.		Authors: Sliwiak, J., Sikorski, M.M., Jaskolski, M.

OCA: Protected "5c9y" [edit=sysop:move=sysop]

OCA — Wed, 08 Jul 2015 13:53:27 GMT

Protected "5c9y" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:53, 8 July 2015

OCA: New page: '''Unreleased structure''' The entry 5c9y is ON HOLD Authors: Sliwiak, J., Sikorski, M.M., Jaskolski, M. Description: Structure of LLPR-10.1A protein partially saturated with trans-zea...

OCA — Wed, 08 Jul 2015 13:53:26 GMT

New page: '''Unreleased structure''' The entry 5c9y is ON HOLD Authors: Sliwiak, J., Sikorski, M.M., Jaskolski, M. Description: Structure of LLPR-10.1A protein partially saturated with trans-zea...

New page

'''Unreleased structure'''

The entry 5c9y is ON HOLD

Authors: Sliwiak, J., Sikorski, M.M., Jaskolski, M.

Description: Structure of LLPR-10.1A protein partially saturated with trans-zeatin.
[[Category: Unreleased Structures]]
[[Category: Sliwiak, J]]
[[Category: Sikorski, M.M]]
[[Category: Jaskolski, M]]