5coj - Revision history

OCA at 11:45, 9 May 2024

OCA — Thu, 09 May 2024 11:45:10 GMT

←Older revision		Revision as of 11:45, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5COJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5COJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [https://pdbe.org/5coj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [https://www.ebi.ac.uk/pdbsum/5coj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5coj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [https://pdbe.org/5coj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [https://www.ebi.ac.uk/pdbsum/5coj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5coj ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:20, 14 June 2023

OCA — Wed, 14 Jun 2023 12:20:21 GMT

←Older revision		Revision as of 12:20, 14 June 2023
Line 3:		Line 3:
	<StructureSection load='5coj' size='340' side='right'caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5coj' size='340' side='right'caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus~~ aureus~~" (rosenbach 1884) zopf 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5COJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5COJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cm5\|5cm5]], [[5gca\|5gca]], [[5cge\|5cge]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [https://pdbe.org/5coj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [https://www.ebi.ac.uk/pdbsum/5coj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5coj ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">thiM, SAR2181 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.50 2.7.1.50] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [~~http~~://pdbe.org/5coj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5coj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5coj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/THIM_STAAR THIM_STAAR]] Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).	+	[https://www.uniprot.org/uniprot/THIM_STAAR THIM_STAAR] Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Transferase~~]]	+	[[Category: Staphylococcus aureus]]
-	[[Category: Betzel, C]]	+	[[Category: Betzel C]]
-	[[Category: Cang, H]]	+	[[Category: Cang H]]
-	[[Category: Drebes, J]]	+	[[Category: Drebes J]]
-	[[Category: Eberle~~, R J~~]]	+	[[Category: Eberle RJ]]
-	[[Category: Kuenz, M]]	+	[[Category: Kuenz M]]
-	[[Category: Oberthuer, D]]	+	[[Category: Oberthuer D]]
-	[[Category: Wrenger, C]]	+	[[Category: Wrenger C]]
-	~~[[Category: Bacterial thiamine biosynthesis]]~~	+
-	~~[[Category: Hydroxyethylthiazole kinase~~]]	+

OCA at 06:08, 10 July 2019

OCA — Wed, 10 Jul 2019 06:08:47 GMT

←Older revision		Revision as of 06:08, 10 July 2019
Line 1:		Line 1:

	==Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.==		==Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.==
-	<StructureSection load='5coj' size='340' side='right' caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5coj' size='340' side='right'caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5COJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5COJ FirstGlance]. <br>
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Betzel, C]]		[[Category: Betzel, C]]

OCA at 06:15, 24 October 2018

OCA — Wed, 24 Oct 2018 06:15:59 GMT

←Older revision		Revision as of 06:15, 24 October 2018
Line 3:		Line 3:
	<StructureSection load='5coj' size='340' side='right' caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5coj' size='340' side='right' caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5COJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5COJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cm5\|5cm5]], [[5gca\|5gca]], [[5cge\|5cge]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cm5\|5cm5]], [[5gca\|5gca]], [[5cge\|5cge]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">thiM, SAR2181 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.50 2.7.1.50] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.50 2.7.1.50] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [http://pdbe.org/5coj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [http://www.ebi.ac.uk/pdbsum/5coj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [http://pdbe.org/5coj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [http://www.ebi.ac.uk/pdbsum/5coj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5coj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 13:00, 11 May 2016

OCA — Wed, 11 May 2016 13:00:27 GMT

←Older revision		Revision as of 13:00, 11 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5coj is ~~ON HOLD~~	+	==Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.==
		+	<StructureSection load='5coj' size='340' side='right' caption='[[5coj]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5coj]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5COJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZE:2-(4-METHYL-THIAZOL-5-YL)-ETHANOL'>TZE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cm5\|5cm5]], [[5gca\|5gca]], [[5cge\|5cge]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.50 2.7.1.50] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5coj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5coj OCA], [http://pdbe.org/5coj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5coj RCSB], [http://www.ebi.ac.uk/pdbsum/5coj PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/THIM_STAAR THIM_STAAR]] Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Infections caused by the methicillin-resistant Staphylococcus aureus (MRSA) are today known to be a substantial threat for global health. Emerging multi-drug resistant bacteria have created a substantial need to identify and discover new drug targets and to develop novel strategies to treat bacterial infections. A promising and so far untapped antibiotic target is the biosynthesis of vitamin B1 (thiamin). Thiamin in its activated form, thiamin pyrophosphate, is an essential co-factor for all organisms. Therefore, thiamin analogous compounds, when introduced into the vitamin B1 biosynthetic pathway and further converted into non-functional co-factors by the bacterium can function as pro-drugs which thus block various co-factor dependent pathways. We characterized one of the key enzymes within the S. aureus vitamin B1 biosynthetic pathway, 5-(hydroxyethyl)-4-methylthiazole kinase (SaThiM; EC 2.7.1.50), a potential target for pro-drug compounds and analyzed the native structure of SaThiM and complexes with the natural substrate 5-(hydroxyethyl)-4-methylthiazole (THZ) and two selected substrate analogues.

-	~~Authors:~~ Drebes, J~~., Kuenz~~, M., ~~Eberle~~, ~~R.J.~~, ~~Oberthuer~~, D., Cang, H., ~~Wrenger~~, C., Betzel, C.	+	Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.,Drebes J, Kunz M, Windshugel B, Kikhney AG, Muller IB, Eberle RJ, Oberthur D, Cang H, Svergun DI, Perbandt M, Betzel C, Wrenger C Sci Rep. 2016 Mar 10;6:22871. doi: 10.1038/srep22871. PMID:26960569<ref>PMID:26960569</ref>

-	~~Description: Structure~~ of ~~Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2~~-(4-~~methyl-1~~,~~3-thiazol-5-yl)ethanol.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5coj" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Transferase]]
		+	[[Category: Betzel, C]]
		+	[[Category: Cang, H]]
	[[Category: Drebes, J]]		[[Category: Drebes, J]]
		+	[[Category: Eberle, R J]]
	[[Category: Kuenz, M]]		[[Category: Kuenz, M]]
	[[Category: Oberthuer, D]]		[[Category: Oberthuer, D]]
	[[Category: Wrenger, C]]		[[Category: Wrenger, C]]
-	[[Category: ~~Eberle, R.J~~]]	+	[[Category: Bacterial thiamine biosynthesis]]
-	[[Category: ~~Betzel, C]]~~	+	[[Category: Hydroxyethylthiazole kinase]]
-	~~[[Category: Cang, H~~]]	+

OCA at 10:39, 16 December 2015

OCA — Wed, 16 Dec 2015 10:39:14 GMT

←Older revision		Revision as of 10:39, 16 December 2015
Line 7:		Line 7:
	Description: Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.		Description: Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Drebes, J]]
	[[Category: Kuenz, M]]		[[Category: Kuenz, M]]
	[[Category: Oberthuer, D]]		[[Category: Oberthuer, D]]
	[[Category: Wrenger, C]]		[[Category: Wrenger, C]]
	[[Category: Eberle, R.J]]		[[Category: Eberle, R.J]]
-	[[Category: Cang, H]]
-	[[Category: Drebes, J]]
	[[Category: Betzel, C]]		[[Category: Betzel, C]]
		+	[[Category: Cang, H]]

OCA: Protected "5coj" [edit=sysop:move=sysop]

OCA — Wed, 29 Jul 2015 13:39:09 GMT

Protected "5coj" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:39, 29 July 2015

OCA: New page: '''Unreleased structure''' The entry 5coj is ON HOLD Authors: Drebes, J., Kuenz, M., Eberle, R.J., Oberthuer, D., Cang, H., Wrenger, C., Betzel, C. Description: Structure of Hydroxyeth...

OCA — Wed, 29 Jul 2015 13:39:08 GMT

New page: '''Unreleased structure''' The entry 5coj is ON HOLD Authors: Drebes, J., Kuenz, M., Eberle, R.J., Oberthuer, D., Cang, H., Wrenger, C., Betzel, C. Description: Structure of Hydroxyeth...

New page

'''Unreleased structure'''

The entry 5coj is ON HOLD

Authors: Drebes, J., Kuenz, M., Eberle, R.J., Oberthuer, D., Cang, H., Wrenger, C., Betzel, C.

Description: Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.
[[Category: Unreleased Structures]]
[[Category: Kuenz, M]]
[[Category: Oberthuer, D]]
[[Category: Wrenger, C]]
[[Category: Eberle, R.J]]
[[Category: Cang, H]]
[[Category: Drebes, J]]
[[Category: Betzel, C]]