5dah - Revision history

OCA at 12:23, 6 March 2024

OCA — Wed, 06 Mar 2024 12:23:29 GMT

←Older revision		Revision as of 12:23, 6 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DAH FirstGlance]. <br>		<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DAH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.611Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [https://pdbe.org/5dah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [https://www.ebi.ac.uk/pdbsum/5dah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dah ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [https://pdbe.org/5dah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [https://www.ebi.ac.uk/pdbsum/5dah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dah ProSAT]</span></td></tr>
	</table>		</table>
Line 11:		Line 12:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN] Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.<ref>PMID:17868029</ref>		[https://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN] Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.<ref>PMID:17868029</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	AF10, a DOT1L cofactor, is required for H3K79 methylation and cooperates with DOT1L in leukemogenesis. However, the molecular mechanism by which AF10 regulates DOT1L-mediated H3K79 methylation is not clear. Here we report that AF10 contains a "reader" domain that couples unmodified H3K27 recognition to H3K79 methylation. An AF10 region consisting of a PHD finger-Zn knuckle-PHD finger (PZP) folds into a single module that recognizes amino acids 22-27 of H3, and this interaction is abrogated by H3K27 modification. Structural studies reveal that H3 binding triggers rearrangement of the PZP module to form an H3(22-27)-accommodating channel and that the unmodified H3K27 side chain is encased in a compact hydrogen-bond acceptor-lined cage. In cells, PZP recognition of H3 is required for H3K79 dimethylation, expression of DOT1L-target genes, and proliferation of DOT1L-addicted leukemic cells. Together, our results uncover a pivotal role for H3K27-via readout by the AF10 PZP domain-in regulating the cancer-associated enzyme DOT1L.
-
-	The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.,Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O Mol Cell. 2015 Oct 15;60(2):319-27. doi: 10.1016/j.molcel.2015.08.019. Epub 2015 , Oct 1. PMID:26439302<ref>PMID:26439302</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5dah" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:28, 21 June 2023

OCA — Wed, 21 Jun 2023 10:28:21 GMT

←Older revision		Revision as of 10:28, 21 June 2023
Line 3:		Line 3:
	<StructureSection load='5dah' size='340' side='right'caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>		<StructureSection load='5dah' size='340' side='right'caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5DAH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DAH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dag\|5dag]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [https://pdbe.org/5dah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [https://www.ebi.ac.uk/pdbsum/5dah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dah ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MLLT10, AF10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [~~http~~://pdbe.org/5dah PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5dah PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5dah ProSAT]</span></td></tr>	+
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN]] Precursor T-cell acute lymphoblastic leukemia. A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein. A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.	+	[https://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN] Precursor T-cell acute lymphoblastic leukemia. A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein. A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN]] Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.<ref>PMID:17868029</ref>	+	[https://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN] Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.<ref>PMID:17868029</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, S]]	+	[[Category: Chen S]]
-	[[Category: Patel~~, D J]]~~	+	[[Category: Patel DJ]]
-	~~[[Category: Epigenetic]]~~	+
-	~~[[Category: H3k27 recognition]]~~	+
-	~~[[Category: Histone tail reader]]~~	+
-	~~[[Category: Peptide binding protein]]~~	+
-	~~[[Category: Phd finger~~]]	+

OCA at 11:20, 25 December 2019

OCA — Wed, 25 Dec 2019 11:20:18 GMT

←Older revision		Revision as of 11:20, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide==		==Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide==
-	<StructureSection load='5dah' size='340' side='right' caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>	+	<StructureSection load='5dah' size='340' side='right'caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DAH FirstGlance]. <br>		<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DAH FirstGlance]. <br>
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Chen, S]]		[[Category: Chen, S]]
	[[Category: Patel, D J]]		[[Category: Patel, D J]]

OCA at 16:46, 15 November 2017

OCA — Wed, 15 Nov 2017 16:46:49 GMT

←Older revision		Revision as of 16:46, 15 November 2017
Line 1:		Line 1:
		+
	==Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide==		==Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide==
	<StructureSection load='5dah' size='340' side='right' caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>		<StructureSection load='5dah' size='340' side='right' caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DAH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DAH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dag\|5dag]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dag\|5dag]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [http://pdbe.org/5dah PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [http://www.ebi.ac.uk/pdbsum/5dah PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MLLT10, AF10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [http://pdbe.org/5dah PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [http://www.ebi.ac.uk/pdbsum/5dah PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dah ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Chen, S]]		[[Category: Chen, S]]
	[[Category: Patel, D J]]		[[Category: Patel, D J]]

OCA at 05:27, 22 October 2015

OCA — Thu, 22 Oct 2015 05:27:03 GMT

←Older revision		Revision as of 05:27, 22 October 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide==
		+	<StructureSection load='5dah' size='340' side='right' caption='[[5dah]], [[Resolution\|resolution]] 2.61Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5dah]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DAH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dag\|5dag]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dah OCA], [http://pdbe.org/5dah PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dah RCSB], [http://www.ebi.ac.uk/pdbsum/5dah PDBsum]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN]] Precursor T-cell acute lymphoblastic leukemia. A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein. A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AF10_HUMAN AF10_HUMAN]] Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.<ref>PMID:17868029</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	AF10, a DOT1L cofactor, is required for H3K79 methylation and cooperates with DOT1L in leukemogenesis. However, the molecular mechanism by which AF10 regulates DOT1L-mediated H3K79 methylation is not clear. Here we report that AF10 contains a "reader" domain that couples unmodified H3K27 recognition to H3K79 methylation. An AF10 region consisting of a PHD finger-Zn knuckle-PHD finger (PZP) folds into a single module that recognizes amino acids 22-27 of H3, and this interaction is abrogated by H3K27 modification. Structural studies reveal that H3 binding triggers rearrangement of the PZP module to form an H3(22-27)-accommodating channel and that the unmodified H3K27 side chain is encased in a compact hydrogen-bond acceptor-lined cage. In cells, PZP recognition of H3 is required for H3K79 dimethylation, expression of DOT1L-target genes, and proliferation of DOT1L-addicted leukemic cells. Together, our results uncover a pivotal role for H3K27-via readout by the AF10 PZP domain-in regulating the cancer-associated enzyme DOT1L.

-	The ~~entry 5dah is ON HOLD until Paper Publication~~	+	The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.,Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O Mol Cell. 2015 Oct 15;60(2):319-27. doi: 10.1016/j.molcel.2015.08.019. Epub 2015 , Oct 1. PMID:26439302<ref>PMID:26439302</ref>

-	~~Authors: Chen~~, S.~~, Patel, D.J~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide~~	+	<div class="pdbe-citations 5dah" style="background-color:#fffaf0;"></div>
-	~~[[Category: Unreleased Structures]]~~	+	== References ==
-	~~[[Category: Patel, D.J]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Chen, S]]		[[Category: Chen, S]]
		+	[[Category: Patel, D J]]
		+	[[Category: Epigenetic]]
		+	[[Category: H3k27 recognition]]
		+	[[Category: Histone tail reader]]
		+	[[Category: Peptide binding protein]]
		+	[[Category: Phd finger]]

OCA at 11:22, 2 September 2015

OCA — Wed, 02 Sep 2015 11:22:39 GMT

←Older revision		Revision as of 11:22, 2 September 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5dah is ON HOLD	+	The entry 5dah is ON HOLD until Paper Publication

	Authors: Chen, S., Patel, D.J.		Authors: Chen, S., Patel, D.J.

OCA: Protected "5dah" [edit=sysop:move=sysop]

OCA — Wed, 26 Aug 2015 12:39:44 GMT

Protected "5dah" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:39, 26 August 2015

OCA: New page: '''Unreleased structure''' The entry 5dah is ON HOLD Authors: Chen, S., Patel, D.J. Description: Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide [[C...

OCA — Wed, 26 Aug 2015 12:39:43 GMT

New page: '''Unreleased structure''' The entry 5dah is ON HOLD Authors: Chen, S., Patel, D.J. Description: Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide [[C...

New page

'''Unreleased structure'''

The entry 5dah is ON HOLD

Authors: Chen, S., Patel, D.J.

Description: Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
[[Category: Unreleased Structures]]
[[Category: Patel, D.J]]
[[Category: Chen, S]]