5dak - Revision history

OCA at 08:44, 27 September 2023

OCA — Wed, 27 Sep 2023 08:44:50 GMT

←Older revision		Revision as of 08:44, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DAK FirstGlance]. <br>		<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DAK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.11Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [https://pdbe.org/5dak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [https://www.ebi.ac.uk/pdbsum/5dak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [https://pdbe.org/5dak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [https://www.ebi.ac.uk/pdbsum/5dak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:28, 21 June 2023

OCA — Wed, 21 Jun 2023 10:28:26 GMT

←Older revision		Revision as of 10:28, 21 June 2023
Line 3:		Line 3:
	<StructureSection load='5dak' size='340' side='right'caption='[[5dak]], [[Resolution\|resolution]] 2.11Å' scene=''>		<StructureSection load='5dak' size='340' side='right'caption='[[5dak]], [[Resolution\|resolution]] 2.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5DAK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DAK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, ~~<scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [https://pdbe.org/5dak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [https://www.ebi.ac.uk/pdbsum/5dak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dal\|5dal]]~~, ~~[[5dcg\|5dcg]], [[5ddl\|5ddl]]~~<~~/td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">GSTP1, FAEES3, GST3~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]~~)~~</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [~~http~~://pdbe.org/5dak PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5dak PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref>	+	[https://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref>

	==See Also==		==See Also==
Line 20:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Glutathione transferase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Morton~~, C J~~]]	+	[[Category: Morton CJ]]
-	[[Category: Parker~~, L J~~]]	+	[[Category: Parker LJ]]
-	[[Category: Parker~~, M W]]~~	+	[[Category: Parker MW]]
-	~~[[Category: Anti-cancer]]~~	+
-	~~[[Category: Metalloid]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:57, 8 April 2020

OCA — Wed, 08 Apr 2020 07:57:27 GMT

←Older revision		Revision as of 07:57, 8 April 2020
Line 1:		Line 1:

	==Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione==		==Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione==
-	<StructureSection load='5dak' size='340' side='right' caption='[[5dak]], [[Resolution\|resolution]] 2.11Å' scene=''>	+	<StructureSection load='5dak' size='340' side='right'caption='[[5dak]], [[Resolution\|resolution]] 2.11Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5DAK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DAK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dal\|5dal]], [[5dcg\|5dcg]], [[5ddl\|5ddl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dal\|5dal]], [[5dcg\|5dcg]], [[5ddl\|5ddl]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTP1, FAEES3, GST3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [http://pdbe.org/5dak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [http://www.ebi.ac.uk/pdbsum/5dak PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [http://pdbe.org/5dak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [http://www.ebi.ac.uk/pdbsum/5dak PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref>		[[http://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref>
		+
		+	==See Also==
		+	*[[Glutathione S-transferase 3D structures\|Glutathione S-transferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 17:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Morton, C J]]		[[Category: Morton, C J]]
	[[Category: Parker, L J]]		[[Category: Parker, L J]]

OCA at 02:06, 11 December 2016

OCA — Sun, 11 Dec 2016 02:06:46 GMT

←Older revision		Revision as of 02:06, 11 December 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5dak is ~~ON HOLD~~ ~~until Nov 23 2017~~	+	==Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione==
-		+	<StructureSection load='5dak' size='340' side='right' caption='[[5dak]], [[Resolution\|resolution]] 2.11Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5dak]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DAK FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dal\|5dal]], [[5dcg\|5dcg]], [[5ddl\|5ddl]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dak OCA], [http://pdbe.org/5dak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dak RCSB], [http://www.ebi.ac.uk/pdbsum/5dak PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dak ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Glutathione transferase]]
		+	[[Category: Morton, C J]]
		+	[[Category: Parker, L J]]
		+	[[Category: Parker, M W]]
		+	[[Category: Anti-cancer]]
		+	[[Category: Metalloid]]
		+	[[Category: Transferase]]

OCA at 10:37, 9 September 2016

OCA — Fri, 09 Sep 2016 10:37:03 GMT

←Older revision		Revision as of 10:37, 9 September 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5dak is ON HOLD until ~~Paper Publication~~	+	The entry 5dak is ON HOLD until Nov 23 2017

	Authors:		Authors:

OCA at 11:48, 15 May 2016

OCA — Sun, 15 May 2016 11:48:45 GMT

←Older revision		Revision as of 11:48, 15 May 2016
Line 3:		Line 3:
	The entry 5dak is ON HOLD until Paper Publication		The entry 5dak is ON HOLD until Paper Publication

-	Authors: ~~Parker, L.J., Parker, M.W., Morton, C.J.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Parker, M.W]]
-	[[Category: Parker, L.J]]
-	[[Category: Morton, C.J]]

OCA at 12:49, 30 September 2015

OCA — Wed, 30 Sep 2015 12:49:35 GMT

←Older revision		Revision as of 12:49, 30 September 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5dak is ON HOLD	+	The entry 5dak is ON HOLD until Paper Publication

	Authors: Parker, L.J., Parker, M.W., Morton, C.J.		Authors: Parker, L.J., Parker, M.W., Morton, C.J.

OCA at 09:59, 9 September 2015

OCA — Wed, 09 Sep 2015 09:59:03 GMT

←Older revision		Revision as of 09:59, 9 September 2015
Line 3:		Line 3:
	The entry 5dak is ON HOLD		The entry 5dak is ON HOLD

-	Authors: Parker, L.J., Parker, M.W., Morton, C. J.	+	Authors: Parker, L.J., Parker, M.W., Morton, C.J.

	Description:		Description:
Line 9:		Line 9:
	[[Category: Parker, M.W]]		[[Category: Parker, M.W]]
	[[Category: Parker, L.J]]		[[Category: Parker, L.J]]
-	[[Category: Morton, C. J]]	+	[[Category: Morton, C.J]]

OCA: Protected "5dak" [edit=sysop:move=sysop]

OCA — Wed, 26 Aug 2015 12:39:52 GMT

Protected "5dak" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:39, 26 August 2015

OCA: New page: '''Unreleased structure''' The entry 5dak is ON HOLD Authors: Parker, L.J., Parker, M.W., Morton, C. J. Description: Category: Unreleased Structures Category: Parker, M.W [[Ca...

OCA — Wed, 26 Aug 2015 12:39:50 GMT

New page: '''Unreleased structure''' The entry 5dak is ON HOLD Authors: Parker, L.J., Parker, M.W., Morton, C. J. Description: Category: Unreleased Structures Category: Parker, M.W [[Ca...

New page

'''Unreleased structure'''

The entry 5dak is ON HOLD

Authors: Parker, L.J., Parker, M.W., Morton, C. J.

Description:
[[Category: Unreleased Structures]]
[[Category: Parker, M.W]]
[[Category: Parker, L.J]]
[[Category: Morton, C. J]]