5dhb - Revision history

OCA at 12:24, 6 March 2024

OCA — Wed, 06 Mar 2024 12:24:40 GMT

←Older revision		Revision as of 12:24, 6 March 2024
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [https://pdbe.org/5dhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [https://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [https://pdbe.org/5dhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [https://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Many high-resolution crystal structures have contributed to our understanding of the reaction pathway for catalysis by DNA and RNA polymerases, but the structural basis of nonenzymatic template-directed RNA replication has not been studied in comparable detail. Here we present crystallographic studies of the binding of ribonucleotide monomers to RNA primer-template complexes, with the goal of improving our understanding of the mechanism of nonenzymatic RNA copying, and of catalysis by polymerases. To explore how activated ribonucleotides recognize and bind to RNA templates, we synthesized an unreactive phosphonate-linked pyrazole analogue of guanosine 5'-phosphoro-2-methylimidazolide (2-MeImpG), a highly activated nucleotide that has been used extensively to study nonenzymatic primer extension. We cocrystallized this analogue with structurally rigidified RNA primer-template complexes carrying single or multiple monomer binding sites, and obtained high-resolution X-ray structures of these complexes. In addition to Watson-Crick base pairing, we repeatedly observed noncanonical guanine:cytidine base pairs in our crystal structures. In most structures, the phosphate and leaving group moieties of the monomers were highly disordered, while in others the distance from O3' of the primer to the phosphorus of the incoming monomer was too great to allow for reaction. We suggest that these effects significantly influence the rate and fidelity of nonenzymatic RNA replication, and that even primitive ribozyme polymerases could enhance RNA replication by enforcing Watson-Crick base pairing between monomers and primer-template complexes, and by bringing the reactive functional groups into closer proximity.
-
-	Unusual Base-Pairing Interactions in Monomer-Template Complexes.,Zhang W, Tam CP, Wang J, Szostak JW ACS Cent Sci. 2016 Dec 28;2(12):916-926. doi: 10.1021/acscentsci.6b00278. Epub, 2016 Nov 2. PMID:28058281<ref>PMID:28058281</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5dhb" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 21:41, 28 June 2023

OCA — Wed, 28 Jun 2023 21:41:38 GMT

←Older revision		Revision as of 21:41, 28 June 2023
Line 3:		Line 3:
	<StructureSection load='5dhb' size='340' side='right'caption='[[5dhb]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='5dhb' size='340' side='right'caption='[[5dhb]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dhb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5DHB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dhb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DHB FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=5GP:GUANOSINE~~-~~5-MONOPHOSPHATE'>5GP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=LCC:[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCC</scene>, <scene name='pdbligand=LCG:[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCG</scene>, <scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=LCC:[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCC</scene>, <scene name='pdbligand=LCG:[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCG</scene>, <scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dhc\|5dhc]], [[5hbw\|5hbw]], [[5hbx\|5hbx]], [[5hby\|5hby]], [[5krg\|5krg]], [[5l00\|5l00]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [https://pdbe.org/5dhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [https://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [~~http~~://pdbe.org/5dhb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 23:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Fahrenbach, A C~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Szostak, J W~~]]	+	[[Category: Fahrenbach AC]]
-	[[Category: ~~Tam, C P~~]]	+	[[Category: Szostak JW]]
-	[[Category: ~~Zhang, W~~]]	+	[[Category: Tam CP]]
-	[[Category: ~~Cooperativity]]~~	+	[[Category: Zhang W]]
-	~~[[Category: Monomer]]~~	+
-	~~[[Category: Rna~~]]	+

OCA at 08:03, 8 April 2020

OCA — Wed, 08 Apr 2020 08:03:32 GMT

←Older revision		Revision as of 08:03, 8 April 2020
Line 1:		Line 1:

	==Cooperativity and Downstream Binding in RNA Replication==		==Cooperativity and Downstream Binding in RNA Replication==
-	<StructureSection load='5dhb' size='340' side='right' caption='[[5dhb]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='5dhb' size='340' side='right'caption='[[5dhb]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dhb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5DHB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dhb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DHB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LCC:[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCC</scene>, <scene name='pdbligand=LCG:[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCG</scene>, <scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LCC:[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCC</scene>, <scene name='pdbligand=LCG:[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCG</scene>, <scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dhc\|5dhc]], [[5hbw\|5hbw]], [[5hbx\|5hbx]], [[5hby\|5hby]], [[5krg\|5krg]], [[5l00\|5l00]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dhc\|5dhc]], [[5hbw\|5hbw]], [[5hbx\|5hbx]], [[5hby\|5hby]], [[5krg\|5krg]], [[5l00\|5l00]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [http://pdbe.org/5dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [http://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [http://pdbe.org/5dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [http://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Fahrenbach, A C]]		[[Category: Fahrenbach, A C]]
	[[Category: Szostak, J W]]		[[Category: Szostak, J W]]

OCA at 08:36, 18 January 2017

OCA — Wed, 18 Jan 2017 08:36:46 GMT

←Older revision		Revision as of 08:36, 18 January 2017
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [http://pdbe.org/5dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [http://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [http://pdbe.org/5dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [http://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Many high-resolution crystal structures have contributed to our understanding of the reaction pathway for catalysis by DNA and RNA polymerases, but the structural basis of nonenzymatic template-directed RNA replication has not been studied in comparable detail. Here we present crystallographic studies of the binding of ribonucleotide monomers to RNA primer-template complexes, with the goal of improving our understanding of the mechanism of nonenzymatic RNA copying, and of catalysis by polymerases. To explore how activated ribonucleotides recognize and bind to RNA templates, we synthesized an unreactive phosphonate-linked pyrazole analogue of guanosine 5'-phosphoro-2-methylimidazolide (2-MeImpG), a highly activated nucleotide that has been used extensively to study nonenzymatic primer extension. We cocrystallized this analogue with structurally rigidified RNA primer-template complexes carrying single or multiple monomer binding sites, and obtained high-resolution X-ray structures of these complexes. In addition to Watson-Crick base pairing, we repeatedly observed noncanonical guanine:cytidine base pairs in our crystal structures. In most structures, the phosphate and leaving group moieties of the monomers were highly disordered, while in others the distance from O3' of the primer to the phosphorus of the incoming monomer was too great to allow for reaction. We suggest that these effects significantly influence the rate and fidelity of nonenzymatic RNA replication, and that even primitive ribozyme polymerases could enhance RNA replication by enforcing Watson-Crick base pairing between monomers and primer-template complexes, and by bringing the reactive functional groups into closer proximity.
		+
		+	Unusual Base-Pairing Interactions in Monomer-Template Complexes.,Zhang W, Tam CP, Wang J, Szostak JW ACS Cent Sci. 2016 Dec 28;2(12):916-926. doi: 10.1021/acscentsci.6b00278. Epub, 2016 Nov 2. PMID:28058281<ref>PMID:28058281</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5dhb" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 02:07, 11 December 2016

OCA — Sun, 11 Dec 2016 02:07:11 GMT

←Older revision		Revision as of 02:07, 11 December 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5dhb is ~~ON HOLD until Paper Publication~~	+	==Cooperativity and Downstream Binding in RNA Replication==
-		+	<StructureSection load='5dhb' size='340' side='right' caption='[[5dhb]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~Authors~~: ~~Zhang~~, W., ~~Fahrenbach~~, A.C., ~~Tam~~, C.P., ~~Szostak~~, J.W.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5dhb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DHB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DHB FirstGlance]. <br>
-	~~Description~~: ~~Cooperativity and Downstream Binding in RNA Replication~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LCC:[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCC</scene>, <scene name='pdbligand=LCG:[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>LCG</scene>, <scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
-	[[Category: Szostak, J.W]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dhc\|5dhc]], [[5hbw\|5hbw]], [[5hbx\|5hbx]], [[5hby\|5hby]], [[5krg\|5krg]], [[5l00\|5l00]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dhb OCA], [http://pdbe.org/5dhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dhb RCSB], [http://www.ebi.ac.uk/pdbsum/5dhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dhb ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Fahrenbach, A C]]
		+	[[Category: Szostak, J W]]
		+	[[Category: Tam, C P]]
	[[Category: Zhang, W]]		[[Category: Zhang, W]]
-	[[Category: ~~Tam, C.P~~]]	+	[[Category: Cooperativity]]
-	[[Category: ~~Fahrenbach, A.C~~]]	+	[[Category: Monomer]]
		+	[[Category: Rna]]

OCA at 11:09, 16 December 2015

OCA — Wed, 16 Dec 2015 11:09:15 GMT

←Older revision		Revision as of 11:09, 16 December 2015
Line 7:		Line 7:
	Description: Cooperativity and Downstream Binding in RNA Replication		Description: Cooperativity and Downstream Binding in RNA Replication
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Zhang, W]]
-	[[Category: Fahrenbach, A.C]]
	[[Category: Szostak, J.W]]		[[Category: Szostak, J.W]]
		+	[[Category: Zhang, W]]
	[[Category: Tam, C.P]]		[[Category: Tam, C.P]]
		+	[[Category: Fahrenbach, A.C]]

OCA at 03:45, 22 October 2015

OCA — Thu, 22 Oct 2015 03:45:52 GMT

←Older revision		Revision as of 03:45, 22 October 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5dhb is ON HOLD	+	The entry 5dhb is ON HOLD until Paper Publication

	Authors: Zhang, W., Fahrenbach, A.C., Tam, C.P., Szostak, J.W.		Authors: Zhang, W., Fahrenbach, A.C., Tam, C.P., Szostak, J.W.

OCA: Protected "5dhb" [edit=sysop:move=sysop]

OCA — Wed, 09 Sep 2015 10:12:01 GMT

Protected "5dhb" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:12, 9 September 2015

OCA: New page: '''Unreleased structure''' The entry 5dhb is ON HOLD Authors: Zhang, W., Fahrenbach, A.C., Tam, C.P., Szostak, J.W. Description: Cooperativity and Downstream Binding in RNA Replication...

OCA — Wed, 09 Sep 2015 10:11:58 GMT

New page: '''Unreleased structure''' The entry 5dhb is ON HOLD Authors: Zhang, W., Fahrenbach, A.C., Tam, C.P., Szostak, J.W. Description: Cooperativity and Downstream Binding in RNA Replication...

New page

'''Unreleased structure'''

The entry 5dhb is ON HOLD

Authors: Zhang, W., Fahrenbach, A.C., Tam, C.P., Szostak, J.W.

Description: Cooperativity and Downstream Binding in RNA Replication
[[Category: Unreleased Structures]]
[[Category: Zhang, W]]
[[Category: Fahrenbach, A.C]]
[[Category: Szostak, J.W]]
[[Category: Tam, C.P]]