5dip - Revision history

OCA at 21:43, 28 June 2023

OCA — Wed, 28 Jun 2023 21:43:14 GMT

←Older revision		Revision as of 21:43, 28 June 2023
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	<StructureSection load='5dip' size='340' side='right'caption='[[5dip]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='5dip' size='340' side='right'caption='[[5dip]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dip]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_33152 Atcc 33152~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5DIP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dip]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DIP FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.097Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:]]</b></td><td class="sblockDat">[[5dik\|5dik~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>lptwr_00386, lpymg_00422 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~446 ATCC 33152])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dip OCA], [https://pdbe.org/5dip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dip RCSB], [https://www.ebi.ac.uk/pdbsum/5dip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dip ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dip OCA], [~~http~~://pdbe.org/5dip PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5dip RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5dip PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5dip ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/A0A0C9P2U2_LEGPN A0A0C9P2U2_LEGPN]] Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.[SAAS:SAAS00088543]	+	[https://www.uniprot.org/uniprot/Q5ZYG6_LEGPH Q5ZYG6_LEGPH]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 33152]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Peroxiredoxin~~]]	+	[[Category: Legionella pneumophila]]
-	[[Category: Chen, X]]	+	[[Category: Chen X]]
-	[[Category: Ge, H]]	+	[[Category: Ge H]]
-	[[Category: Gong, X]]	+	[[Category: Gong X]]
-	[[Category: Zhang, N]]	+	[[Category: Zhang N]]
-	~~[[Category: Alkylhydroperoxidase]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 08:05, 8 April 2020

OCA — Wed, 08 Apr 2020 08:05:26 GMT

←Older revision		Revision as of 08:05, 8 April 2020
Line 1:		Line 1:
		+
	==Crystal structure of lpg0406 in reduced form from Legionella pneumophila==		==Crystal structure of lpg0406 in reduced form from Legionella pneumophila==
-	<StructureSection load='5dip' size='340' side='right' caption='[[5dip]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='5dip' size='340' side='right'caption='[[5dip]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5dip]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIP OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5DIP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5dip]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33152 Atcc 33152]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DIP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dik\|5dik]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dik\|5dik]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lptwr_00386, lpymg_00422 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=446 ATCC 33152])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dip OCA], [http://pdbe.org/5dip PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dip RCSB], [http://www.ebi.ac.uk/pdbsum/5dip PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dip OCA], [http://pdbe.org/5dip PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dip RCSB], [http://www.ebi.ac.uk/pdbsum/5dip PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dip ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 33152]]
		+	[[Category: Large Structures]]
	[[Category: Peroxiredoxin]]		[[Category: Peroxiredoxin]]
	[[Category: Chen, X]]		[[Category: Chen, X]]

OCA at 03:51, 16 October 2015

OCA — Fri, 16 Oct 2015 03:51:41 GMT

←Older revision		Revision as of 03:51, 16 October 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of lpg0406 in reduced form from Legionella pneumophila==
		+	<StructureSection load='5dip' size='340' side='right' caption='[[5dip]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5dip]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DIP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5dik\|5dik]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dip OCA], [http://pdbe.org/5dip PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dip RCSB], [http://www.ebi.ac.uk/pdbsum/5dip PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A0C9P2U2_LEGPN A0A0C9P2U2_LEGPN]] Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.[SAAS:SAAS00088543]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Lpg0406, a hypothetical protein from Legionella pneumophila, belongs to carboxymuconolactone decarboxylase (CMD) family. We determined the crystal structure of lpg0406 both in its apo and reduced form. The structures reveal that lpg0406 forms a hexamer and have disulfide exchange properties. The protein has an all-helical fold with a conserved thioredoxin-like active site CXXC motif and a proton relay system similar to that of alkylhydroperoxidase from Mycobacterium tuberculosis (MtAhpD), suggesting that lpg0406 might function as an enzyme with peroxidase activity and involved in antioxidant defense. A comparison of the size and the surface topology of the putative substrate-binding region between lpg0406 and MtAhpD indicates that the two enzymes accommodate the different substrate preferences. The structural findings will enhance understanding of the CMD family protein structure and its various functions.

-	~~The entry 5dip is ON HOLD~~	+	Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila.,Chen X, Hu Y, Yang B, Gong X, Zhang N, Niu L, Wu Y, Ge H Protein Sci. 2015 Sep 24. doi: 10.1002/pro.2811. PMID:26402328<ref>PMID:26402328</ref>

-	~~Authors: Chen~~, X.~~, Gong, X~~.~~, Zhang, N., Ge, H~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of lpg0406 in reduced form from Legionella pneumophila~~	+	<div class="pdbe-citations 5dip" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Peroxiredoxin]]
		+	[[Category: Chen, X]]
		+	[[Category: Ge, H]]
	[[Category: Gong, X]]		[[Category: Gong, X]]
-	[[Category: Ge, H]]
-	[[Category: Chen, X]]
	[[Category: Zhang, N]]		[[Category: Zhang, N]]
		+	[[Category: Alkylhydroperoxidase]]
		+	[[Category: Oxidoreductase]]

OCA: Protected "5dip" [edit=sysop:move=sysop]

OCA — Wed, 09 Sep 2015 10:16:21 GMT

Protected "5dip" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:16, 9 September 2015

OCA: New page: '''Unreleased structure''' The entry 5dip is ON HOLD Authors: Chen, X., Gong, X., Zhang, N., Ge, H. Description: Crystal structure of lpg0406 in reduced form from Legionella pneumophil...

OCA — Wed, 09 Sep 2015 10:16:19 GMT

New page: '''Unreleased structure''' The entry 5dip is ON HOLD Authors: Chen, X., Gong, X., Zhang, N., Ge, H. Description: Crystal structure of lpg0406 in reduced form from Legionella pneumophil...

New page

'''Unreleased structure'''

The entry 5dip is ON HOLD

Authors: Chen, X., Gong, X., Zhang, N., Ge, H.

Description: Crystal structure of lpg0406 in reduced form from Legionella pneumophila
[[Category: Unreleased Structures]]
[[Category: Gong, X]]
[[Category: Ge, H]]
[[Category: Chen, X]]
[[Category: Zhang, N]]