5ekq - Revision history

OCA at 06:32, 5 July 2023

OCA — Wed, 05 Jul 2023 06:32:15 GMT

←Older revision		Revision as of 06:32, 5 July 2023
Line 3:		Line 3:
	<StructureSection load='5ekq' size='340' side='right'caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>		<StructureSection load='5ekq' size='340' side='right'caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>bamA, yaeT, yzzN, yzzY, b0177, JW0172 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~83333 ECOLI])~~, ~~bamD, yfiO, b2595, JW2577 (~~[~~http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), bamC, dapX, nlpB, b2477, JW2462 (~~[~~http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI~~]~~), bamE, smpA, b2617, JW2598 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=83333 ECOLI])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.392Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ekq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekq OCA], [~~http~~://pdbe.org/5ekq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ekq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ekq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ekq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ekq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekq OCA], [https://pdbe.org/5ekq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ekq RCSB], [https://www.ebi.ac.uk/pdbsum/5ekq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ekq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/BAME_ECOLI BAME_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. May modulate the conformation of BamA, likely through interactions with BamD.<ref>PMID:17404237</ref> <ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:22178970</ref> <ref>PMID:21207987</ref> <ref>PMID:21586578</ref> [[http://www.uniprot.org/uniprot/BAMA_ECOLI BAMA_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.<ref>PMID:15951436</ref> <ref>PMID:16102012</ref> <ref>PMID:16824102</ref> <ref>PMID:20378773</ref> <ref>PMID:21823654</ref> [[http://www.uniprot.org/uniprot/BAMC_ECOLI BAMC_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD.[HAMAP-Rule:MF_00924]<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:22178970</ref> [[http://www.uniprot.org/uniprot/BAMD_ECOLI BAMD_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. Probably involved in transient protein interactions.[HAMAP-Rule:MF_00922]<ref>PMID:16824102</ref> <ref>PMID:20378773</ref> <ref>PMID:21586578</ref> <ref>PMID:21823654</ref> <ref>PMID:22281737</ref>	+	[https://www.uniprot.org/uniprot/BAMA_ECOLI BAMA_ECOLI] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.<ref>PMID:15951436</ref> <ref>PMID:16102012</ref> <ref>PMID:16824102</ref> <ref>PMID:20378773</ref> <ref>PMID:21823654</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bakelar, J]]	+	[[Category: Bakelar J]]
-	[[Category: Buchanan~~, S K~~]]	+	[[Category: Buchanan SK]]
-	[[Category: Noinaj, N]]	+	[[Category: Noinaj N]]
-	~~[[Category: Beta-barrel]]~~	+
-	~~[[Category: Insertase]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Outer membrane protein~~]]	+

OCA at 16:07, 11 December 2019

OCA — Wed, 11 Dec 2019 16:07:26 GMT

←Older revision		Revision as of 16:07, 11 December 2019
Line 1:		Line 1:

	==The structure of the BamACDE subcomplex from E. coli==		==The structure of the BamACDE subcomplex from E. coli==
-	<StructureSection load='5ekq' size='340' side='right' caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>	+	<StructureSection load='5ekq' size='340' side='right'caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 5ekq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ekq" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Bam complex 3D structures\|Bam complex 3D structures]]
		+	*[[Insertase\|Insertase]]
	== References ==		== References ==
	<references/>		<references/>
Line 23:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Bakelar, J]]		[[Category: Bakelar, J]]
	[[Category: Buchanan, S K]]		[[Category: Buchanan, S K]]

OCA at 12:38, 6 November 2017

OCA — Mon, 06 Nov 2017 12:38:41 GMT

←Older revision		Revision as of 12:38, 6 November 2017
Line 1:		Line 1:
		+
	==The structure of the BamACDE subcomplex from E. coli==		==The structure of the BamACDE subcomplex from E. coli==
	<StructureSection load='5ekq' size='340' side='right' caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>		<StructureSection load='5ekq' size='340' side='right' caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ekq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekq OCA], [http://pdbe.org/5ekq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ekq RCSB], [http://www.ebi.ac.uk/pdbsum/5ekq PDBsum]</span></td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bamA, yaeT, yzzN, yzzY, b0177, JW0172 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), bamD, yfiO, b2595, JW2577 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), bamC, dapX, nlpB, b2477, JW2462 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), bamE, smpA, b2617, JW2598 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ekq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekq OCA], [http://pdbe.org/5ekq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ekq RCSB], [http://www.ebi.ac.uk/pdbsum/5ekq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ekq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 20:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecoli]]
	[[Category: Bakelar, J]]		[[Category: Bakelar, J]]
	[[Category: Buchanan, S K]]		[[Category: Buchanan, S K]]

OCA at 17:01, 20 January 2016

OCA — Wed, 20 Jan 2016 17:01:17 GMT

←Older revision		Revision as of 17:01, 20 January 2016
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==The structure of the BamACDE subcomplex from E. coli==
		+	<StructureSection load='5ekq' size='340' side='right' caption='[[5ekq]], [[Resolution\|resolution]] 3.39Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5ekq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EKQ FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ekq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ekq OCA], [http://pdbe.org/5ekq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ekq RCSB], [http://www.ebi.ac.uk/pdbsum/5ekq PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BAME_ECOLI BAME_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. May modulate the conformation of BamA, likely through interactions with BamD.<ref>PMID:17404237</ref> <ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:22178970</ref> <ref>PMID:21207987</ref> <ref>PMID:21586578</ref> [[http://www.uniprot.org/uniprot/BAMA_ECOLI BAMA_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.<ref>PMID:15951436</ref> <ref>PMID:16102012</ref> <ref>PMID:16824102</ref> <ref>PMID:20378773</ref> <ref>PMID:21823654</ref> [[http://www.uniprot.org/uniprot/BAMC_ECOLI BAMC_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD.[HAMAP-Rule:MF_00924]<ref>PMID:20378773</ref> <ref>PMID:21823654</ref> <ref>PMID:22178970</ref> [[http://www.uniprot.org/uniprot/BAMD_ECOLI BAMD_ECOLI]] Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. Probably involved in transient protein interactions.[HAMAP-Rule:MF_00922]<ref>PMID:16824102</ref> <ref>PMID:20378773</ref> <ref>PMID:21586578</ref> <ref>PMID:21823654</ref> <ref>PMID:22281737</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	beta-Barrel outer membrane proteins (OMPs) are found in the outer membranes of Gram-negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200-kilodalton five-component complex called the beta-barrel assembly machinery (BAM) complex has been implicated in the biogenesis of OMPs. We report the structure of the BAM complex from Escherichia coli, revealing that binding of BamCDE modulates the conformation of BamA, the central component, which may serve to regulate the BAM complex. The periplasmic domain of BamA was in a closed state that prevents access to the barrel lumen, which indicates substrate OMPs may not be threaded through the barrel during biogenesis. Further, conformational shifts in the barrel domain lead to opening of the exit pore and rearrangement at the lateral gate.

-	The ~~entry 5ekq is ON HOLD until Paper Publication~~	+	The structure of the beta-barrel assembly machinery complex.,Bakelar J, Buchanan SK, Noinaj N Science. 2016 Jan 8;351(6269):180-6. doi: 10.1126/science.aad3460. PMID:26744406<ref>PMID:26744406</ref>

-	~~Authors: Bakelar~~, J.~~, Buchanan,~~ S.~~K., Noinaj, N~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~:	+	<div class="pdbe-citations 5ekq" style="background-color:#fffaf0;"></div>
-	~~[[Category: Unreleased Structures]]~~	+	== References ==
-	~~[[Category: Buchanan, S.K]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bakelar, J]]		[[Category: Bakelar, J]]
		+	[[Category: Buchanan, S K]]
	[[Category: Noinaj, N]]		[[Category: Noinaj, N]]
		+	[[Category: Beta-barrel]]
		+	[[Category: Insertase]]
		+	[[Category: Membrane protein]]
		+	[[Category: Outer membrane protein]]

OCA at 17:18, 13 January 2016

OCA — Wed, 13 Jan 2016 17:18:07 GMT

←Older revision		Revision as of 17:18, 13 January 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5ekq is ON HOLD	+	The entry 5ekq is ON HOLD until Paper Publication

	Authors: Bakelar, J., Buchanan, S.K., Noinaj, N.		Authors: Bakelar, J., Buchanan, S.K., Noinaj, N.

OCA: Protected "5ekq" [edit=sysop:move=sysop]

OCA — Tue, 01 Dec 2015 02:59:26 GMT

Protected "5ekq" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:59, 1 December 2015

OCA: New page: '''Unreleased structure''' The entry 5ekq is ON HOLD Authors: Bakelar, J., Buchanan, S.K., Noinaj, N. Description: Category: Unreleased Structures Category: Buchanan, S.K [[Ca...

OCA — Tue, 01 Dec 2015 02:59:24 GMT

New page: '''Unreleased structure''' The entry 5ekq is ON HOLD Authors: Bakelar, J., Buchanan, S.K., Noinaj, N. Description: Category: Unreleased Structures Category: Buchanan, S.K [[Ca...

New page

'''Unreleased structure'''

The entry 5ekq is ON HOLD

Authors: Bakelar, J., Buchanan, S.K., Noinaj, N.

Description:
[[Category: Unreleased Structures]]
[[Category: Buchanan, S.K]]
[[Category: Bakelar, J]]
[[Category: Noinaj, N]]