5eua - Revision history

OCA at 08:24, 12 July 2023

OCA — Wed, 12 Jul 2023 08:24:38 GMT

←Older revision		Revision as of 08:24, 12 July 2023
Line 1:		Line 1:

	==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam==		==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam==
-	<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='5eua' size='340' side='right'caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5EUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EUA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eoe\|5eoe]], [[5eoo\|5eoo]], [[5eph\|5eph]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bla(BEL1), blaBEL-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [https://pdbe.org/5eua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [https://www.ebi.ac.uk/pdbsum/5eua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [~~http~~://pdbe.org/5eua PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5eua PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q3SAW3_PSEAI Q3SAW3_PSEAI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Beta-lactamase]]~~	+	[[Category: Large Structures]]
-	~~[[Category: Benvenuti, M]]~~	+
-	~~[[Category: Docquier, J D]]~~	+
-	~~[[Category: Luca, F De]]~~	+
-	~~[[Category: Mangani, S]]~~	+
-	~~[[Category: Pozzi, C]]~~	+
-	~~[[Category: Extended-spectrum beta-lactamase]]~~	+
-	~~[[Category: Hydrolase-antibiotic complex]]~~	+
-	~~[[Category: Oxacephem antibiotic~~]]	+
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
		+	[[Category: Benvenuti M]]
		+	[[Category: De Luca F]]
		+	[[Category: Docquier JD]]
		+	[[Category: Mangani S]]
		+	[[Category: Pozzi C]]

OCA at 06:52, 31 January 2018

OCA — Wed, 31 Jan 2018 06:52:18 GMT

←Older revision		Revision as of 06:52, 31 January 2018
Line 3:		Line 3:
	<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EUA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eoe\|5eoe]], [[5eoo\|5eoo]], [[5eph\|5eph]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eoe\|5eoe]], [[5eoo\|5eoo]], [[5eph\|5eph]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bla(BEL1), blaBEL-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [http://pdbe.org/5eua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [http://www.ebi.ac.uk/pdbsum/5eua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [http://pdbe.org/5eua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [http://www.ebi.ac.uk/pdbsum/5eua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Beta-lactamase\|Beta-lactamase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:42, 9 December 2016

OCA — Fri, 09 Dec 2016 19:42:12 GMT

←Older revision		Revision as of 19:42, 9 December 2016
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactamase\|Beta-lactamase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:15, 19 October 2016

OCA — Wed, 19 Oct 2016 17:15:57 GMT

←Older revision		Revision as of 17:15, 19 October 2016
Line 3:		Line 3:
	<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxh 4mxh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EUA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eoe\|5eoe]], [[5eoo\|5eoo]], [[5eph\|5eph]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eoe\|5eoe]], [[5eoo\|5eoo]], [[5eph\|5eph]]</td></tr>

OCA at 14:28, 5 October 2016

OCA — Wed, 05 Oct 2016 14:28:36 GMT

←Older revision		Revision as of 14:28, 5 October 2016
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [http://pdbe.org/5eua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [http://www.ebi.ac.uk/pdbsum/5eua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [http://pdbe.org/5eua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [http://www.ebi.ac.uk/pdbsum/5eua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BEL-1 is an acquired class A ESBL found in P. aeruginosa clinical isolates from Belgium, which is divergent from other ESBLs (max. identity, 54% with GES-type enzymes). This enzyme is efficiently inhibited by clavulanate, imipenem and moxalactam. Crystals of BEL-1 were obtained at pH 5.6 and the structure of native BEL-1 was determined from orthorhombic and monoclinic crystal forms, at 1.60-A and 1.48 A resolution, respectively. By soaking native BEL-1 crystals, complexes with imipenem (monoclinic form, 1.79 A res.) and moxalactam (orthorhombic form, 1.85 A res.) were also obtained. In the acyl-enzyme complexes, imipenem and moxalactam differ by the position of the alpha-substituent and of the carbonyl oxygen (in or out the oxyanion hole). More surprisingly, the Omega-loop, which includes the catalytically-relevant residue Glu166, was found in different conformations in the various subunits, resulting in the Glu166 side chain to be rotated outwards the active site or even in displacements of its Calpha atom up to approx. 10 A. A BEL-1 variant showing the single Leu162Phe substitution (BEL-2) confers a higher level of resistance to CAZ, CTX and FEP and shows significantly lower KM values as compared to those of BEL-1, especially with oxyiminocephalosporins. BEL-1 Leu162 is located at the beginning of the Omega-loop, and surrounded by Phe72, Leu139, Leu148 and Leu169 (contact distances, 3.8-4.0 A). This small hydrophobic cavity could not reasonably accommodate the bulkier Phe162 found in BEL-2 without altering neighboring residues or the Omega-loop itself, thus likely causing an important alteration of the enzyme kinetic properties.
		+
		+	Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and its Complex with Moxalactam and Imipenem.,Pozzi C, De Luca F, Benvenuti M, Poirel L, Nordmann P, Rossolini GM, Mangani S, Docquier JD Antimicrob Agents Chemother. 2016 Sep 26. pii: AAC.00936-16. PMID:27671060<ref>PMID:27671060</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5eua" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:48, 21 September 2016

OCA — Wed, 21 Sep 2016 13:48:27 GMT

←Older revision		Revision as of 13:48, 21 September 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5eua is ~~ON HOLD until Paper Publication~~	+	==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam==
-		+	<StructureSection load='5eua' size='340' side='right' caption='[[5eua]], [[Resolution\|resolution]] 1.85Å' scene=''>
-	~~Authors~~: ~~Pozzi~~, C., ~~De Luca~~, F., ~~Benvenuti~~, M., ~~Docquier, J~~.D., ~~Mangani, S~~.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5eua]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EUA FirstGlance]. <br>
-	~~Description: Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Moxalactam~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3P7:(2R)-2-[(1R)-1-{[(2R)-2-CARBOXY-2-(4-HYDROXYPHENYL)ACETYL]AMINO}-1-METHOXY-2-OXOETHYL]-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>3P7</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eoe\|5eoe]], [[5eoo\|5eoo]], [[5eph\|5eph]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eua OCA], [http://pdbe.org/5eua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eua RCSB], [http://www.ebi.ac.uk/pdbsum/5eua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eua ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-lactamase]]
	[[Category: Benvenuti, M]]		[[Category: Benvenuti, M]]
-	[[Category: De Luca, F]]	+	[[Category: Docquier, J D]]
-	[[Category: ~~Docquier~~, ~~J.D~~]]	+	[[Category: Luca, F De]]
		+	[[Category: Mangani, S]]
	[[Category: Pozzi, C]]		[[Category: Pozzi, C]]
-	[[Category: ~~Mangani, S~~]]	+	[[Category: Extended-spectrum beta-lactamase]]
		+	[[Category: Hydrolase-antibiotic complex]]
		+	[[Category: Oxacephem antibiotic]]
		+	[[Category: Pseudomonas aeruginosa]]

OCA at 05:43, 14 July 2016

OCA — Thu, 14 Jul 2016 05:43:19 GMT

←Older revision		Revision as of 05:43, 14 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5eua is ON HOLD	+	The entry 5eua is ON HOLD until Paper Publication

	Authors: Pozzi, C., De Luca, F., Benvenuti, M., Docquier, J.D., Mangani, S.		Authors: Pozzi, C., De Luca, F., Benvenuti, M., Docquier, J.D., Mangani, S.

OCA at 20:37, 12 July 2016

OCA — Tue, 12 Jul 2016 20:37:02 GMT

←Older revision		Revision as of 20:37, 12 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5eua is ON HOLD ~~until Paper Publication~~	+	The entry 5eua is ON HOLD

	Authors: Pozzi, C., De Luca, F., Benvenuti, M., Docquier, J.D., Mangani, S.		Authors: Pozzi, C., De Luca, F., Benvenuti, M., Docquier, J.D., Mangani, S.

OCA at 12:35, 15 May 2016

OCA — Sun, 15 May 2016 12:35:38 GMT

←Older revision		Revision as of 12:35, 15 May 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5eua is ON HOLD	+	The entry 5eua is ON HOLD until Paper Publication

	Authors: Pozzi, C., De Luca, F., Benvenuti, M., Docquier, J.D., Mangani, S.		Authors: Pozzi, C., De Luca, F., Benvenuti, M., Docquier, J.D., Mangani, S.

OCA: Protected "5eua" [edit=sysop:move=sysop]

OCA — Tue, 01 Dec 2015 03:22:39 GMT

Protected "5eua" [edit=sysop:move=sysop]

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Revision as of 03:22, 1 December 2015