5fuq - Revision history

OCA at 00:56, 28 December 2023

OCA — Thu, 28 Dec 2023 00:56:09 GMT

←Older revision		Revision as of 00:56, 28 December 2023
Line 13:		Line 13:
	==See Also==		==See Also==
	*[[NADPH dehydrogenase\|NADPH dehydrogenase]]		*[[NADPH dehydrogenase\|NADPH dehydrogenase]]
-	*[[Quinone reductase\|Quinone reductase]]	+	*[[Quinone reductase 3D structures\|Quinone reductase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:27, 26 July 2023

OCA — Wed, 26 Jul 2023 13:27:28 GMT

←Older revision		Revision as of 13:27, 26 July 2023
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	<StructureSection load='5fuq' size='340' side='right'caption='[[5fuq]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='5fuq' size='340' side='right'caption='[[5fuq]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.04Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [~~http~~://pdbe.org/5fuq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [https://pdbe.org/5fuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [https://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.	+	[https://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

	==See Also==		==See Also==
	*[[NADPH dehydrogenase\|NADPH dehydrogenase]]		*[[NADPH dehydrogenase\|NADPH dehydrogenase]]
		+	*[[Quinone reductase\|Quinone reductase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gavira~~, J A~~]]	+	[[Category: Gavira JA]]
-	[[Category: Medina-Carmona, E]]	+	[[Category: Medina-Carmona E]]
-	[[Category: Pey~~, A L]]~~	+	[[Category: Pey AL]]
-	~~[[Category: Dicoumarol]]~~	+
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Nadph-quinone oxidoreductase 1]]~~	+
-	~~[[Category: Nqo1]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 07:38, 6 May 2020

OCA — Wed, 06 May 2020 07:38:18 GMT

←Older revision		Revision as of 07:38, 6 May 2020
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL==		==CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL==
-	<StructureSection load='5fuq' size='340' side='right' caption='[[5fuq]], [[Resolution\|resolution]] 2.04Å' scene=''>	+	<StructureSection load='5fuq' size='340' side='right'caption='[[5fuq]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [http://pdbe.org/5fuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [http://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [http://pdbe.org/5fuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [http://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.		[[http://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
		+
		+	==See Also==
		+	*[[NADPH dehydrogenase\|NADPH dehydrogenase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Gavira, J A]]		[[Category: Gavira, J A]]
	[[Category: Medina-Carmona, E]]		[[Category: Medina-Carmona, E]]

OCA at 01:30, 11 March 2017

OCA — Sat, 11 Mar 2017 01:30:41 GMT

←Older revision		Revision as of 01:30, 11 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5fuq ~~is ON HOLD until Paper Publication~~	+	==CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL==
-		+	<StructureSection load='5fuq' size='340' side='right' caption='[[5fuq]], [[Resolution\|resolution]] 2.04Å' scene=''>
-	~~Authors~~: ~~Gavira, J~~.A., ~~Medina~~-~~Carmona~~, E., ~~Pey~~, A.L.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>
-	~~Description~~: ~~CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2] </span></td></tr>
-	[[~~Category~~: ~~Gavira~~, J.A]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [http://pdbe.org/5fuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [http://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>
-	[[Category: ~~Pey~~, A.L]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Gavira, J A]]
	[[Category: Medina-Carmona, E]]		[[Category: Medina-Carmona, E]]
		+	[[Category: Pey, A L]]
		+	[[Category: Dicoumarol]]
		+	[[Category: Fad]]
		+	[[Category: Nadph-quinone oxidoreductase 1]]
		+	[[Category: Nqo1]]
		+	[[Category: Oxidoreductase]]

OCA at 00:25, 21 February 2016

OCA — Sun, 21 Feb 2016 00:25:00 GMT

←Older revision		Revision as of 00:25, 21 February 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5fuq is ON HOLD	+	The entry 5fuq is ON HOLD until Paper Publication

	Authors: Gavira, J.A., Medina-Carmona, E., Pey, A.L.		Authors: Gavira, J.A., Medina-Carmona, E., Pey, A.L.

OCA: Protected "5fuq" [edit=sysop:move=sysop]

OCA — Wed, 03 Feb 2016 13:28:37 GMT

Protected "5fuq" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:28, 3 February 2016

OCA: New page: '''Unreleased structure''' The entry 5fuq is ON HOLD Authors: Gavira, J.A., Medina-Carmona, E., Pey, A.L. Description: CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL...

OCA — Wed, 03 Feb 2016 13:28:35 GMT

New page: '''Unreleased structure''' The entry 5fuq is ON HOLD Authors: Gavira, J.A., Medina-Carmona, E., Pey, A.L. Description: CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL...

New page

'''Unreleased structure'''

The entry 5fuq is ON HOLD

Authors: Gavira, J.A., Medina-Carmona, E., Pey, A.L.

Description: CRYSTAL STRUCTURE OF THE H80R VARIANT OF NQO1 BOUND TO DICOUMAROL
[[Category: Unreleased Structures]]
[[Category: Gavira, J.A]]
[[Category: Pey, A.L]]
[[Category: Medina-Carmona, E]]