5fvw - Revision history

OCA at 13:29, 26 July 2023

OCA — Wed, 26 Jul 2023 13:29:01 GMT

←Older revision		Revision as of 13:29, 26 July 2023
Line 3:		Line 3:
	<StructureSection load='5fvw' size='340' side='right'caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='5fvw' size='340' side='right'caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5FVW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FVW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fvo\|5fvo]], [[5fvp\|5fvp]], [[5fvq\|5fvq]], [[5fvr\|5fvr]], [[5fvs\|5fvs]], [[5fvt\|5fvt]], [[5fvu\|5fvu]], [[5fvv\|5fvv]], [[5fvx\|5fvx]], [[5fvy\|5fvy]], [[5fvz\|5fvz]], [[5fw0\|5fw0]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [~~http~~://pdbe.org/5fvw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5fvw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5fvw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [https://pdbe.org/5fvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [https://www.ebi.ac.uk/pdbsum/5fvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fvw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NOS1_HUMAN NOS1_HUMAN]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.	+	[https://www.uniprot.org/uniprot/NOS1_HUMAN NOS1_HUMAN] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Li, H]]	+	[[Category: Li H]]
-	[[Category: Poulos~~, T L]]~~	+	[[Category: Poulos TL]]
-	~~[[Category: Nitric oxide synthase]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 07:39, 6 May 2020

OCA — Wed, 06 May 2020 07:39:45 GMT

←Older revision		Revision as of 07:39, 6 May 2020
Line 1:		Line 1:

	==Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl)ethyl) pyridin-2-amine==		==Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl)ethyl) pyridin-2-amine==
-	<StructureSection load='5fvw' size='340' side='right' caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='5fvw' size='340' side='right'caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5FVW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FVW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fvo\|5fvo]], [[5fvp\|5fvp]], [[5fvq\|5fvq]], [[5fvr\|5fvr]], [[5fvs\|5fvs]], [[5fvt\|5fvt]], [[5fvu\|5fvu]], [[5fvv\|5fvv]], [[5fvx\|5fvx]], [[5fvy\|5fvy]], [[5fvz\|5fvz]], [[5fw0\|5fw0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fvo\|5fvo]], [[5fvp\|5fvp]], [[5fvq\|5fvq]], [[5fvr\|5fvr]], [[5fvs\|5fvs]], [[5fvt\|5fvt]], [[5fvu\|5fvu]], [[5fvv\|5fvv]], [[5fvx\|5fvx]], [[5fvy\|5fvy]], [[5fvz\|5fvz]], [[5fw0\|5fw0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [http://pdbe.org/5fvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [http://www.ebi.ac.uk/pdbsum/5fvw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fvw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [http://pdbe.org/5fvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [http://www.ebi.ac.uk/pdbsum/5fvw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fvw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5fvw" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5fvw" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Nitric Oxide Synthase 3D structures\|Nitric Oxide Synthase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Li, H]]		[[Category: Li, H]]
	[[Category: Poulos, T L]]		[[Category: Poulos, T L]]
	[[Category: Nitric oxide synthase]]		[[Category: Nitric oxide synthase]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 12:38, 16 November 2017

OCA — Thu, 16 Nov 2017 12:38:18 GMT

←Older revision		Revision as of 12:38, 16 November 2017
Line 3:		Line 3:
	<StructureSection load='5fvw' size='340' side='right' caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='5fvw' size='340' side='right' caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FVW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FVW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fvo\|5fvo]], [[5fvp\|5fvp]], [[5fvq\|5fvq]], [[5fvr\|5fvr]], [[5fvs\|5fvs]], [[5fvt\|5fvt]], [[5fvu\|5fvu]], [[5fvv\|5fvv]], [[5fvx\|5fvx]], [[5fvy\|5fvy]], [[5fvz\|5fvz]], [[5fw0\|5fw0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fvo\|5fvo]], [[5fvp\|5fvp]], [[5fvq\|5fvq]], [[5fvr\|5fvr]], [[5fvs\|5fvs]], [[5fvt\|5fvt]], [[5fvu\|5fvu]], [[5fvv\|5fvv]], [[5fvx\|5fvx]], [[5fvy\|5fvy]], [[5fvz\|5fvz]], [[5fw0\|5fw0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [http://pdbe.org/5fvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [http://www.ebi.ac.uk/pdbsum/5fvw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [http://pdbe.org/5fvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [http://www.ebi.ac.uk/pdbsum/5fvw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fvw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Li, H]]		[[Category: Li, H]]
	[[Category: Poulos, T L]]		[[Category: Poulos, T L]]
	[[Category: Nitric oxide synthase]]		[[Category: Nitric oxide synthase]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 18:45, 12 May 2016

OCA — Thu, 12 May 2016 18:45:52 GMT

←Older revision		Revision as of 18:45, 12 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5fvw is ~~ON HOLD until Paper~~ Publication	+	==Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl)ethyl) pyridin-2-amine==
		+	<StructureSection load='5fvw' size='340' side='right' caption='[[5fvw]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5fvw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FVW FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=W66:4-METHYL-6-(2-(5-(3-(METHYLAMINO)PROPYL)PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE'>W66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fvo\|5fvo]], [[5fvp\|5fvp]], [[5fvq\|5fvq]], [[5fvr\|5fvr]], [[5fvs\|5fvs]], [[5fvt\|5fvt]], [[5fvu\|5fvu]], [[5fvv\|5fvv]], [[5fvx\|5fvx]], [[5fvy\|5fvy]], [[5fvz\|5fvz]], [[5fw0\|5fw0]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fvw OCA], [http://pdbe.org/5fvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fvw RCSB], [http://www.ebi.ac.uk/pdbsum/5fvw PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NOS1_HUMAN NOS1_HUMAN]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Neuronal nitric oxide synthase (nNOS) is an important therapeutic target for the treatment of various neurodegenerative disorders. A major challenge in the design of nNOS inhibitors focuses on potency in humans and selectivity over other NOS isoforms. Here we report potent and selective human nNOS inhibitors based on the 2-aminopyridine scaffold with a central pyridine linker. Compound 14j, the most promising inhibitor in this study, exhibits excellent potency for rat nNOS (Ki = 16 nM) with 828-fold n/e and 118-fold n/i selectivity with a Ki value of 13 nM against human nNOS with 1761-fold human n/e selectivity. Compound 14j also displayed good metabolic stability in human liver microsomes, low plasma protein binding, and minimal binding to cytochromes P450 (CYPs), although it had little to no Caco-2 permeability.

-	~~Authors: Li~~, H., Poulos, T.L.	+	Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.,Wang HY, Qin Y, Li H, Roman LJ, Martasek P, Poulos TL, Silverman RB J Med Chem. 2016 Apr 20. PMID:27050842<ref>PMID:27050842</ref>

-	~~Description: Structure~~ of ~~human nNOS R354A G357D mutant heme domain in complex with 4~~-~~methyl~~-~~6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl)ethyl) pyridin-2-amine~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	~~[[Category: Poulos, T.L]]~~	+	<div class="pdbe-citations 5fvw" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Li, H]]		[[Category: Li, H]]
		+	[[Category: Poulos, T L]]
		+	[[Category: Nitric oxide synthase]]
		+	[[Category: Oxidoreductase]]

OCA at 12:15, 2 March 2016

OCA — Wed, 02 Mar 2016 12:15:36 GMT

←Older revision		Revision as of 12:15, 2 March 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5fvw is ON HOLD	+	The entry 5fvw is ON HOLD until Paper Publication

	Authors: Li, H., Poulos, T.L.		Authors: Li, H., Poulos, T.L.

OCA: Protected "5fvw" [edit=sysop:move=sysop]

OCA — Sun, 21 Feb 2016 00:28:44 GMT

Protected "5fvw" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:28, 21 February 2016

OCA: New page: '''Unreleased structure''' The entry 5fvw is ON HOLD Authors: Li, H., Poulos, T.L. Description: Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-...

OCA — Sun, 21 Feb 2016 00:28:43 GMT

New page: '''Unreleased structure''' The entry 5fvw is ON HOLD Authors: Li, H., Poulos, T.L. Description: Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-...

New page

'''Unreleased structure'''

The entry 5fvw is ON HOLD

Authors: Li, H., Poulos, T.L.

Description: Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl)ethyl) pyridin-2-amine
[[Category: Unreleased Structures]]
[[Category: Poulos, T.L]]
[[Category: Li, H]]