5fwz - Revision history

OCA at 13:30, 26 July 2023

OCA — Wed, 26 Jul 2023 13:30:05 GMT

←Older revision		Revision as of 13:30, 26 July 2023
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	<StructureSection load='5fwz' size='340' side='right'caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5fwz' size='340' side='right'caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Fashe Fashe~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fasciola_hepatica Fasciola hepatica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[5fx0\|5fx0]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [~~http~~://pdbe.org/5fwz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5fwz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [https://pdbe.org/5fwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [https://www.ebi.ac.uk/pdbsum/5fwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A0B5GUS3_FASHE A0A0B5GUS3_FASHE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Fashe~~]]	+	[[Category: Fasciola hepatica]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Nguyen~~, T H]]~~	+	[[Category: Nguyen TH]]
-	~~[[Category: Raaij, M J.van~~]]	+	[[Category: Thomas CM]]
-	[[Category: Thomas~~, C M~~]]	+	[[Category: Timson DJ]]
-	[[Category: Timson~~, D J~~]]	+	[[Category: Van Raaij MJ]]
-	[[Category: ~~Calcium-binding protein~~]]	+

OCA at 07:41, 6 May 2020

OCA — Wed, 06 May 2020 07:41:04 GMT

←Older revision		Revision as of 07:41, 6 May 2020
Line 1:		Line 1:

	==Fasciola hepatica calcium binding protein FhCaBP2: Structure of the dynein light chain-like domain. P41212 mercury derivative.==		==Fasciola hepatica calcium binding protein FhCaBP2: Structure of the dynein light chain-like domain. P41212 mercury derivative.==
-	<StructureSection load='5fwz' size='340' side='right' caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='5fwz' size='340' side='right'caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fashe Fashe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fashe Fashe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [http://pdbe.org/5fwz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [http://www.ebi.ac.uk/pdbsum/5fwz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [http://pdbe.org/5fwz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [http://www.ebi.ac.uk/pdbsum/5fwz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Fashe]]		[[Category: Fashe]]
		+	[[Category: Large Structures]]
	[[Category: Nguyen, T H]]		[[Category: Nguyen, T H]]
	[[Category: Raaij, M J.van]]		[[Category: Raaij, M J.van]]

OCA at 20:31, 24 January 2018

OCA — Wed, 24 Jan 2018 20:31:20 GMT

←Older revision		Revision as of 20:31, 24 January 2018
Line 3:		Line 3:
	<StructureSection load='5fwz' size='340' side='right' caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='5fwz' size='340' side='right' caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fashe Fashe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Fashe]]
	[[Category: Nguyen, T H]]		[[Category: Nguyen, T H]]
	[[Category: Raaij, M J.van]]		[[Category: Raaij, M J.van]]

OCA at 18:43, 12 July 2016

OCA — Tue, 12 Jul 2016 18:43:08 GMT

←Older revision		Revision as of 18:43, 12 July 2016
Line 6:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [http://pdbe.org/5fwz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [http://www.ebi.ac.uk/pdbsum/5fwz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [http://pdbe.org/5fwz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [http://www.ebi.ac.uk/pdbsum/5fwz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:05, 13 May 2016

OCA — Fri, 13 May 2016 12:05:10 GMT

←Older revision		Revision as of 12:05, 13 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5fwz is ~~ON HOLD until Paper~~ Publication	+	==Fasciola hepatica calcium binding protein FhCaBP2: Structure of the dynein light chain-like domain. P41212 mercury derivative.==
		+	<StructureSection load='5fwz' size='340' side='right' caption='[[5fwz]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5fwz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FWZ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fx0\|5fx0]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwz OCA], [http://pdbe.org/5fwz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwz RCSB], [http://www.ebi.ac.uk/pdbsum/5fwz PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The common liver fluke Fasciola hepatica causes an increasing burden on human and animal health, partly because of the spread of drug-resistant isolates. As a consequence, there is considerable interest in developing new drugs to combat liver fluke infections. A group of potential targets is a family of calcium-binding proteins which combine an N-terminal domain with two EF-hand motifs and a C-terminal domain with predicted similarity to dynein light chains (DLC-like domain). The function of these proteins is unknown, although in several species, they have been localised to the tegument, an important structure at the host-parasite interface. Here, we report the X-ray crystal structure of the DLC-like domain of F. hepatica calcium-binding protein 2 (FhCaBP2), solved using single-wavelength anomalous diffraction and refined at 2.3 A resolution in two different crystal forms. The FhCaBP2 DLC-like domain has a structure similar to other DLC domains, with an anti-parallel beta-sheet packed against an alpha-helical hairpin. Like other DLC domains, it dimerises through its beta2-strand, which extends in an arch and forms the fifth strand in an extended beta-sheet of the other monomer. The structure provides molecular details of the dimerisation of FhCaBP2, the first example from this family of parasite proteins.

-	~~Authors~~: Nguyen~~, T.H.~~, Thomas~~, C.M.~~, Timson~~, D.J.~~, van Raaij~~, M~~.J.	+	Fasciola hepatica calcium-binding protein FhCaBP2: structure of the dynein light chain-like domain.,Nguyen TH, Thomas CM, Timson DJ, van Raaij MJ Parasitol Res. 2016 Apr 16. PMID:27083189<ref>PMID:27083189</ref>

-	~~Description: Fasciola hepatica calcium binding protein FhCaBP2: Structure~~ of the ~~dynein light chain-like domain~~. ~~P41212 mercury derivative~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Thomas~~, C.M]]	+	<div class="pdbe-citations 5fwz" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Timson~~, ~~D.J~~]]	+	== References ==
-	[[Category: ~~Van Raaij~~, M.J]]	+	<references/>
-	[[Category: ~~Nguyen, T.H~~]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Nguyen, T H]]
		+	[[Category: Raaij, M J.van]]
		+	[[Category: Thomas, C M]]
		+	[[Category: Timson, D J]]
		+	[[Category: Calcium-binding protein]]

OCA at 00:52, 10 March 2016

OCA — Thu, 10 Mar 2016 00:52:29 GMT

←Older revision		Revision as of 00:52, 10 March 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5fwz is ON HOLD	+	The entry 5fwz is ON HOLD until Paper Publication

	Authors: Nguyen, T.H., Thomas, C.M., Timson, D.J., van Raaij, M.J.		Authors: Nguyen, T.H., Thomas, C.M., Timson, D.J., van Raaij, M.J.

OCA: Protected "5fwz" [edit=sysop:move=sysop]

OCA — Wed, 02 Mar 2016 12:18:27 GMT

Protected "5fwz" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:18, 2 March 2016

OCA: New page: '''Unreleased structure''' The entry 5fwz is ON HOLD Authors: Nguyen, T.H., Thomas, C.M., Timson, D.J., van Raaij, M.J. Description: Fasciola hepatica calcium binding protein FhCaBP2: ...

OCA — Wed, 02 Mar 2016 12:18:25 GMT

New page: '''Unreleased structure''' The entry 5fwz is ON HOLD Authors: Nguyen, T.H., Thomas, C.M., Timson, D.J., van Raaij, M.J. Description: Fasciola hepatica calcium binding protein FhCaBP2: ...

New page

'''Unreleased structure'''

The entry 5fwz is ON HOLD

Authors: Nguyen, T.H., Thomas, C.M., Timson, D.J., van Raaij, M.J.

Description: Fasciola hepatica calcium binding protein FhCaBP2: Structure of the dynein light chain-like domain. P41212 mercury derivative.
[[Category: Unreleased Structures]]
[[Category: Thomas, C.M]]
[[Category: Timson, D.J]]
[[Category: Van Raaij, M.J]]
[[Category: Nguyen, T.H]]