5fyo - Revision history

OCA at 13:32, 26 July 2023

OCA — Wed, 26 Jul 2023 13:32:10 GMT

←Older revision		Revision as of 13:32, 26 July 2023
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	<StructureSection load='5fyo' size='340' side='right'caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='5fyo' size='340' side='right'caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Achromobacter_georgiopolitanum Achromobacter georgiopolitanum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5FYO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FYO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=CA:CALCIUM+ION'>CA</scene~~>, ~~<scene name='pdbligand=EDO:~~1~~,2-ETHANEDIOL'>EDO</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[5fyp\|5fyp]]~~, ~~[[5fyr\|5fyr]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyo OCA], [~~http~~://pdbe.org/5fyo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5fyo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5fyo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyo OCA], [https://pdbe.org/5fyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fyo RCSB], [https://www.ebi.ac.uk/pdbsum/5fyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyo ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A1S4NYD4_PSESP A0A1S4NYD4_PSESP]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Achromobacter georgiopolitanum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Blagova, E]]	+	[[Category: Pseudomonas sp]]
-	[[Category: Blicher~~, T H~~]]	+	[[Category: Blagova E]]
-	[[Category: Lebedev~~, A A~~]]	+	[[Category: Blicher TH]]
-	[[Category: Moroz~~, O V~~]]	+	[[Category: Lebedev AA]]
-	[[Category: Norgaard, A]]	+	[[Category: Moroz OV]]
-	[[Category: Segura~~, D R~~]]	+	[[Category: Norgaard A]]
-	[[Category: Wilson~~, K S]]~~	+	[[Category: Segura DR]]
-	~~[[Category: Calcium-dependent]]~~	+	[[Category: Wilson KS]]
-	~~[[Category: Gram-negative]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase apo form]]~~	+
-	~~[[Category: Pi-plc~~]]	+

OCA at 13:01, 10 May 2019

OCA — Fri, 10 May 2019 13:01:20 GMT

←Older revision		Revision as of 13:01, 10 May 2019
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	==Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 1==		==Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 1==
-	<StructureSection load='5fyo' size='340' side='right' caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='5fyo' size='340' side='right'caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_georgiopolitanum Achromobacter georgiopolitanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FYO FirstGlance]. <br>		<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_georgiopolitanum Achromobacter georgiopolitanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FYO FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 5fyo" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5fyo" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Phospholipase C\|Phospholipase C]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Achromobacter georgiopolitanum]]		[[Category: Achromobacter georgiopolitanum]]
		+	[[Category: Large Structures]]
	[[Category: Blagova, E]]		[[Category: Blagova, E]]
	[[Category: Blicher, T H]]		[[Category: Blicher, T H]]

OCA at 23:07, 15 November 2017

OCA — Wed, 15 Nov 2017 23:07:06 GMT

←Older revision		Revision as of 23:07, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='5fyo' size='340' side='right' caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='5fyo' size='340' side='right' caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FYO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_georgiopolitanum Achromobacter georgiopolitanum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FYO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fyp\|5fyp]], [[5fyr\|5fyr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fyp\|5fyp]], [[5fyr\|5fyr]]</td></tr>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Achromobacter georgiopolitanum]]
	[[Category: Blagova, E]]		[[Category: Blagova, E]]
	[[Category: Blicher, T H]]		[[Category: Blicher, T H]]

OCA at 16:31, 25 January 2017

OCA — Wed, 25 Jan 2017 16:31:29 GMT

←Older revision		Revision as of 16:31, 25 January 2017
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyo OCA], [http://pdbe.org/5fyo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fyo RCSB], [http://www.ebi.ac.uk/pdbsum/5fyo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyo OCA], [http://pdbe.org/5fyo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fyo RCSB], [http://www.ebi.ac.uk/pdbsum/5fyo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyo ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial phosphoinositide-specific phospholipases C (PI-PLCs) are the smallest members of the PI-PLC family, which includes much larger mammalian enzymes responsible for signal transduction as well as enzymes from protozoan parasites, yeast and plants. Eukaryotic PI-PLCs have calcium in the active site, but this is absent in the known structures of Gram-positive bacteria, where its role is instead played by arginine. In addition to their use in a number of industrial applications, the bacterial enzymes attract special interest because they can serve as convenient models of the catalytic domains of eukaryotic enzymes for in vitro activity studies. Here, the structure of a PI-PLC from Pseudomonas sp. 62186 is reported, the first from a Gram-negative bacterium and the first of a native bacterial PI-PLC with calcium present in the active site. Solution of the structure posed particular problems owing to the low sequence identity of available homologous structures. Its dependence on calcium for catalysis makes this enzyme a better model for studies of the mammalian PI-PLCs than the previously used calcium-independent bacterial PI-PLCs.
		+
		+	The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium.,Moroz OV, Blagova E, Lebedev AA, Norgaard A, Segura DR, Blicher TH, Brask J, Wilson KS Acta Crystallogr D Struct Biol. 2017 Jan 1;73(Pt 1):32-44. doi:, 10.1107/S2059798316019616. Epub 2017 Jan 1. PMID:28045383<ref>PMID:28045383</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5fyo" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 00:38, 19 January 2017

OCA — Thu, 19 Jan 2017 00:38:25 GMT

←Older revision		Revision as of 00:38, 19 January 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5fyo is ON HOLD until Paper Publication~~	+	==Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 1==
-		+	<StructureSection load='5fyo' size='340' side='right' caption='[[5fyo]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~Authors: Moroz, O.V., Blagova, E., Lebedev, A.A., Norgaard, A., Segura, D.R., Blicher, T.H., Wilson, K.S.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5fyo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FYO FirstGlance]. <br>
-	~~Description:~~ Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 1	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fyp\|5fyp]], [[5fyr\|5fyr]]</td></tr>
-	[[~~Category~~: ~~Segura~~, D.R]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fyo OCA], [http://pdbe.org/5fyo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fyo RCSB], [http://www.ebi.ac.uk/pdbsum/5fyo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fyo ProSAT]</span></td></tr>
-	[[Category: ~~Wilson~~, ~~K.S~~]]	+	</table>
-	[[Category: Blicher, T.H]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Blagova, E]]
		+	[[Category: Blicher, T H]]
		+	[[Category: Lebedev, A A]]
		+	[[Category: Moroz, O V]]
	[[Category: Norgaard, A]]		[[Category: Norgaard, A]]
-	[[Category: ~~Lebedev~~, ~~A.A~~]]	+	[[Category: Segura, D R]]
-	[[Category: ~~Blagova~~, E]]	+	[[Category: Wilson, K S]]
-	[[Category: ~~Moroz, O.V~~]]	+	[[Category: Calcium-dependent]]
		+	[[Category: Gram-negative]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase apo form]]
		+	[[Category: Pi-plc]]

OCA: Protected "5fyo" [edit=sysop:move=sysop]

OCA — Tue, 10 May 2016 23:14:53 GMT

Protected "5fyo" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:14, 10 May 2016

OCA: New page: '''Unreleased structure''' The entry 5fyo is ON HOLD until Paper Publication Authors: Moroz, O.V., Blagova, E., Lebedev, A.A., Norgaard, A., Segura, D.R., Blicher, T.H., Wilson, K.S. D...

OCA — Tue, 10 May 2016 23:14:52 GMT

New page: '''Unreleased structure''' The entry 5fyo is ON HOLD until Paper Publication Authors: Moroz, O.V., Blagova, E., Lebedev, A.A., Norgaard, A., Segura, D.R., Blicher, T.H., Wilson, K.S. D...

New page

'''Unreleased structure'''

The entry 5fyo is ON HOLD until Paper Publication

Authors: Moroz, O.V., Blagova, E., Lebedev, A.A., Norgaard, A., Segura, D.R., Blicher, T.H., Wilson, K.S.

Description: Calcium-dependent phosphoinositol-specific phospholipase C from a Gram-negative bacterium, Pseudomonas sp, apo form, crystal form 1
[[Category: Unreleased Structures]]
[[Category: Segura, D.R]]
[[Category: Wilson, K.S]]
[[Category: Blicher, T.H]]
[[Category: Norgaard, A]]
[[Category: Lebedev, A.A]]
[[Category: Blagova, E]]
[[Category: Moroz, O.V]]