5g2a - Revision history

OCA at 13:35, 26 July 2023

OCA — Wed, 26 Jul 2023 13:35:52 GMT

←Older revision		Revision as of 13:35, 26 July 2023
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	<StructureSection load='5g2a' size='340' side='right'caption='[[5g2a]], [[Resolution\|resolution]] 2.17Å' scene=''>		<StructureSection load='5g2a' size='340' side='right'caption='[[5g2a]], [[Resolution\|resolution]] 2.17Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g2a]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Flavobacteria_bacterium_s1~~-08 ~~Flavobacteria bacterium s1~~-08]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2A OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5G2A FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g2a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nonlabens_marinus_S1-08 Nonlabens marinus S1-08]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G2A FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>~~, ~~<scene name='pdbligand=RET:RETINAL'>RET</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.17Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[5g28\|5g28]]~~, ~~[[5g29\|5g29]], [[5g2c\|5g2c]], [[5g2d\|5g2d]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5g2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2a OCA], [~~http~~://pdbe.org/5g2a PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5g2a RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5g2a PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2a ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2a OCA], [https://pdbe.org/5g2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g2a RCSB], [https://www.ebi.ac.uk/pdbsum/5g2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2a ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/W8VZW3_9FLAO W8VZW3_9FLAO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Flavobacteria bacterium s1-08]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Cha, J S~~]]	+	[[Category: Nonlabens marinus S1-08]]
-	[[Category: ~~Cho, H S~~]]	+	[[Category: Cha JS]]
-	[[Category: ~~Jun, S H~~]]	+	[[Category: Cho HS]]
-	[[Category: ~~Kim, H Y~~]]	+	[[Category: Jun SH]]
-	[[Category: Kim~~, J H~~]]	+	[[Category: Kim HY]]
-	[[Category: Kim~~, K L~~]]	+	[[Category: Kim JH]]
-	[[Category: ~~Kwon, S K~~]]	+	[[Category: Kim KL]]
-	[[Category: ~~Signaling protein~~]]	+	[[Category: Kwon SK]]

OCA at 06:36, 13 May 2020

OCA — Wed, 13 May 2020 06:36:02 GMT

←Older revision		Revision as of 06:36, 13 May 2020
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	==The crystal structure of light-driven chloride pump ClR at pH 6.0 with Bromide ion.==		==The crystal structure of light-driven chloride pump ClR at pH 6.0 with Bromide ion.==
-	<StructureSection load='5g2a' size='340' side='right' caption='[[5g2a]], [[Resolution\|resolution]] 2.17Å' scene=''>	+	<StructureSection load='5g2a' size='340' side='right'caption='[[5g2a]], [[Resolution\|resolution]] 2.17Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g2a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2A OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5G2A FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g2a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Flavobacteria_bacterium_s1-08 Flavobacteria bacterium s1-08]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5G2A FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g28\|5g28]], [[5g29\|5g29]], [[5g2c\|5g2c]], [[5g2d\|5g2d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g28\|5g28]], [[5g29\|5g29]], [[5g2c\|5g2c]], [[5g2d\|5g2d]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5g2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2a OCA], [http://pdbe.org/5g2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2a RCSB], [http://www.ebi.ac.uk/pdbsum/5g2a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2a ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5g2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2a OCA], [http://pdbe.org/5g2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2a RCSB], [http://www.ebi.ac.uk/pdbsum/5g2a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2a ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 5g2a" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5g2a" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Rhodopsin 3D structures\|Rhodopsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Flavobacteria bacterium s1-08]]
		+	[[Category: Large Structures]]
	[[Category: Cha, J S]]		[[Category: Cha, J S]]
	[[Category: Cho, H S]]		[[Category: Cho, H S]]

OCA at 17:21, 19 October 2016

OCA — Wed, 19 Oct 2016 17:21:59 GMT

←Older revision		Revision as of 17:21, 19 October 2016
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-	'''Unreleased structure'''

-	The ~~entry~~ 5g2a is ~~ON HOLD until Paper~~ Publication	+	==The crystal structure of light-driven chloride pump ClR at pH 6.0 with Bromide ion.==
		+	<StructureSection load='5g2a' size='340' side='right' caption='[[5g2a]], [[Resolution\|resolution]] 2.17Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5g2a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G2A FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g28\|5g28]], [[5g29\|5g29]], [[5g2c\|5g2c]], [[5g2d\|5g2d]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2a OCA], [http://pdbe.org/5g2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2a RCSB], [http://www.ebi.ac.uk/pdbsum/5g2a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2a ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A novel light-driven chloride-pumping rhodopsin (ClR) containing an 'NTQ motif' in its putative ion conduction pathway has been discovered and functionally characterized in a genomic analysis study of a marine bacterium. Here we report the crystal structure of ClR from the flavobacterium Nonlabens marinus S1-08(T) determined under two conditions at 2.0 and 1.56 A resolutions. The structures reveal two chloride-binding sites, one around the protonated Schiff base and the other on a cytoplasmic loop. We identify a '3 omega motif' formed by three non-consecutive aromatic amino acids that is correlated with the B-C loop orientation. Detailed ClR structural analyses with functional studies in E. coli reveal the chloride ion transduction pathway. Our results help understand the molecular mechanism and physiological role of ClR and provide a structural basis for optogenetic applications.

-	~~Authors: Kim~~, K~~.L.~~, Kwon~~, S.K.~~, Jun~~, S.H.~~, Cha~~, J.S.~~, Kim, H~~.Y.~~, Kim, J.H.~~, Cho, H~~.S.	+	Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif.,Kim K, Kwon SK, Jun SH, Cha JS, Kim H, Lee W, Kim JF, Cho HS Nat Commun. 2016 Aug 24;7:12677. doi: 10.1038/ncomms12677. PMID:27554809<ref>PMID:27554809</ref>

-	~~Description: The crystal structure~~ of ~~light-driven chloride pump ClR at pH 6~~.~~0 with Bromide ion~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Kim~~, J.H]]	+	<div class="pdbe-citations 5g2a" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Kwon~~, S.K]]	+	== References ==
-	[[Category: Kim, H.Y]]	+	<references/>
-	[[Category: Kim, ~~K.L~~]]	+	__TOC__
-	[[Category: ~~Cho~~, ~~H.S~~]]	+	</StructureSection>
-	[[Category: ~~Cha~~, J.S]]	+	[[Category: Cha, J S]]
-	[[Category: ~~Jun, S.H~~]]	+	[[Category: Cho, H S]]
		+	[[Category: Jun, S H]]
		+	[[Category: Kim, H Y]]
		+	[[Category: Kim, J H]]
		+	[[Category: Kim, K L]]
		+	[[Category: Kwon, S K]]
		+	[[Category: Signaling protein]]

OCA at 11:35, 1 June 2016

OCA — Wed, 01 Jun 2016 11:35:11 GMT

←Older revision		Revision as of 11:35, 1 June 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5g2a is ON HOLD	+	The entry 5g2a is ON HOLD until Paper Publication

	Authors: Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.		Authors: Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.

OCA: Protected "5g2a" [edit=sysop:move=sysop]

OCA — Tue, 10 May 2016 23:23:46 GMT

Protected "5g2a" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:23, 10 May 2016

OCA: New page: '''Unreleased structure''' The entry 5g2a is ON HOLD Authors: Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S. Description: The crystal structure of light-d...

OCA — Tue, 10 May 2016 23:23:44 GMT

New page: '''Unreleased structure''' The entry 5g2a is ON HOLD Authors: Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S. Description: The crystal structure of light-d...

New page

'''Unreleased structure'''

The entry 5g2a is ON HOLD

Authors: Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.

Description: The crystal structure of light-driven chloride pump ClR at pH 6.0 with Bromide ion.
[[Category: Unreleased Structures]]
[[Category: Kim, J.H]]
[[Category: Kwon, S.K]]
[[Category: Kim, H.Y]]
[[Category: Kim, K.L]]
[[Category: Cho, H.S]]
[[Category: Cha, J.S]]
[[Category: Jun, S.H]]