5g2y - Revision history

OCA at 13:36, 26 July 2023

OCA — Wed, 26 Jul 2023 13:36:50 GMT

←Older revision		Revision as of 13:36, 26 July 2023
Line 3:		Line 3:
	<SX load='5g2y' size='340' side='right' viewer='molstar' caption='[[5g2y]], [[Resolution\|resolution]] 4.50Å' scene=''>		<SX load='5g2y' size='340' side='right' viewer='molstar' caption='[[5g2y]], [[Resolution\|resolution]] 4.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5g2x\|5g2x]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 4.5Å</td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~">~~<b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>~~[~~http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase~~]~~, with EC number [http://www~~.~~brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span>~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [https://pdbe.org/5g2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [https://www.ebi.ac.uk/pdbsum/5g2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2y ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [~~http~~://pdbe.org/5g2y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5g2y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2y ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 20:
	__TOC__		__TOC__
	</SX>		</SX>
		+	[[Category: Lactococcus lactis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: RNA-directed DNA polymerase]]~~	+	[[Category: Agrawal RK]]
-	[[Category: Agrawal~~, R K~~]]	+	[[Category: Belfort M]]
-	[[Category: Belfort, M]]	+	[[Category: Kaushal PS]]
-	[[Category: Kaushal~~, P S~~]]	+	[[Category: Piazza CL]]
-	[[Category: Piazza~~, C L~~]]	+	[[Category: Qu G]]
-	[[Category: Qu, G]]	+	[[Category: Shigematsu H]]
-	[[Category: Shigematsu, H]]	+	[[Category: Wang HW]]
-	[[Category: Wang~~, H W~~]]	+	[[Category: Wang J]]
-	[[Category: Wang, J]]	+
-	~~[[Category: Group ii intron]]~~	+
-	~~[[Category: Intron-encoded protein]]~~	+
-	~~[[Category: Retrotransposons and spliceosom]]~~	+
-	~~[[Category: Ribonucleoprotein]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 20:01, 10 April 2020

OCA — Fri, 10 Apr 2020 20:01:06 GMT

←Older revision		Revision as of 20:01, 10 April 2020
Line 3:		Line 3:
	<SX load='5g2y' size='340' side='right' viewer='molstar' caption='[[5g2y]], [[Resolution\|resolution]] 4.50Å' scene=''>		<SX load='5g2y' size='340' side='right' viewer='molstar' caption='[[5g2y]], [[Resolution\|resolution]] 4.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g2x\|5g2x]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g2x\|5g2x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [http://pdbe.org/5g2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [http://www.ebi.ac.uk/pdbsum/5g2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [http://pdbe.org/5g2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [http://www.ebi.ac.uk/pdbsum/5g2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2y ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:25, 6 March 2020

OCA — Fri, 06 Mar 2020 18:25:50 GMT

←Older revision		Revision as of 18:25, 6 March 2020
Line 1:		Line 1:

	==Structure a of Group II Intron Complexed with its Reverse Transcriptase==		==Structure a of Group II Intron Complexed with its Reverse Transcriptase==
-	<~~StructureSection~~ load='5g2y' size='340' side='right' caption='[[5g2y]], [[Resolution\|resolution]] 4.50Å' scene=''>	+	<SX load='5g2y' size='340' side='right' viewer='molstar' caption='[[5g2y]], [[Resolution\|resolution]] 4.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>
Line 20:		Line 20:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: RNA-directed DNA polymerase]]		[[Category: RNA-directed DNA polymerase]]
	[[Category: Agrawal, R K]]		[[Category: Agrawal, R K]]

OCA at 02:37, 13 July 2016

OCA — Wed, 13 Jul 2016 02:37:08 GMT

←Older revision		Revision as of 02:37, 13 July 2016
Line 6:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g2x\|5g2x]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5g2x\|5g2x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [http://pdbe.org/5g2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [http://www.ebi.ac.uk/pdbsum/5g2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [http://pdbe.org/5g2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [http://www.ebi.ac.uk/pdbsum/5g2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2y ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA: Protected "5g2y" [edit=sysop:move=sysop]

OCA — Wed, 11 May 2016 05:46:17 GMT

Protected "5g2y" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:46, 11 May 2016

OCA: New page: ==Structure a of Group II Intron Complexed with its Reverse Transcriptase==
OCA — Wed, 11 May 2016 05:46:15 GMT

New page: ==Structure a of Group II Intron Complexed with its Reverse Transcriptase== <StructureSection load='5g2y' size='340' side='right' caption='5g2y, resolution 4.50Å'...

New page

==Structure a of Group II Intron Complexed with its Reverse Transcriptase==
<StructureSection load='5g2y' size='340' side='right' caption='[[5g2y]], [[Resolution|resolution]] 4.50Å' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5g2y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G2Y FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5g2x|5g2x]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2y OCA], [http://pdbe.org/5g2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g2y RCSB], [http://www.ebi.ac.uk/pdbsum/5g2y PDBsum]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Bacterial group II introns are large catalytic RNAs related to nuclear spliceosomal introns and eukaryotic retrotransposons. They self-splice, yielding mature RNA, and integrate into DNA as retroelements. A fully active group II intron forms a ribonucleoprotein complex comprising the intron ribozyme and an intron-encoded protein that performs multiple activities including reverse transcription, in which intron RNA is copied into the DNA target. Here we report cryo-EM structures of an endogenously spliced Lactococcus lactis group IIA intron in its ribonucleoprotein complex form at 3.8-A resolution and in its protein-depleted form at 4.5-A resolution, revealing functional coordination of the intron RNA with the protein. Remarkably, the protein structure reveals a close relationship between the reverse transcriptase catalytic domain and telomerase, whereas the active splicing center resembles the spliceosomal Prp8 protein. These extraordinary similarities hint at intricate ancestral relationships and provide new insights into splicing and retromobility.

Structure of a group II intron in complex with its reverse transcriptase.,Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW Nat Struct Mol Biol. 2016 May 2. doi: 10.1038/nsmb.3220. PMID:27136327<ref>PMID:27136327</ref>

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5g2y" style="background-color:#fffaf0;"></div>
== References ==
<references/>
TOC
</StructureSection>
[[Category: RNA-directed DNA polymerase]]
[[Category: Agrawal, R K]]
[[Category: Belfort, M]]
[[Category: Kaushal, P S]]
[[Category: Piazza, C L]]
[[Category: Qu, G]]
[[Category: Shigematsu, H]]
[[Category: Wang, H W]]
[[Category: Wang, J]]
[[Category: Group ii intron]]
[[Category: Intron-encoded protein]]
[[Category: Retrotransposons and spliceosom]]
[[Category: Ribonucleoprotein]]
[[Category: Transferase]]