5g5k - Revision history

OCA at 07:23, 1 May 2024

OCA — Wed, 01 May 2024 07:23:14 GMT

←Older revision		Revision as of 07:23, 1 May 2024
Line 10:		Line 10:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/NAGZ_PSEAE NAGZ_PSEAE] Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.[HAMAP-Rule:MF_00364]		[https://www.uniprot.org/uniprot/NAGZ_PSEAE NAGZ_PSEAE] Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.[HAMAP-Rule:MF_00364]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The N-acetylglucosaminidase NagZ of Pseudomonas aeruginosa catalyzes the first cytoplasmic step in recycling of muropeptides, cell-wall-derived natural products. This reaction regulates gene expression for the beta-lactam resistance enzyme, beta-lactamase. The enzyme catalyzes hydrolysis of N-acetyl-beta-d-glucosamine-(1-->4)-1,6-anhydro-N-acetyl-beta-d-muramyl-peptide (1) to N-acetyl-beta-d-glucosamine (2) and 1,6-anhydro-N-acetyl-beta-d-muramyl-peptide (3). The structural and functional aspects of catalysis by NagZ were investigated by a total of seven X-ray structures, three computational models based on the X-ray structures, molecular-dynamics simulations and mutagenesis. The structural insights came from the unbound state and complexes of NagZ with the substrate, products and a mimetic of the transient oxocarbenium species, which were prepared by synthesis. The mechanism involves a histidine as acid/base catalyst, which is unique for glycosidases. The turnover process utilizes covalent modification of D244, requiring two transition-state species and is regulated by coordination with a zinc ion. The analysis provides a seamless continuum for the catalytic cycle, incorporating large motions by four loops that surround the active site.
-
-	Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa.,Acebron I, Mahasenan KV, De Benedetti S, Lee M, Artola-Recolons C, Hesek D, Wang H, Hermoso JA, Mobashery S J Am Chem Soc. 2017 May 10. doi: 10.1021/jacs.7b01626. PMID:28482153<ref>PMID:28482153</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5g5k" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 15:
	*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]		*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]
	*[[Beta-N-acetylhexosaminidase 3D structures\|Beta-N-acetylhexosaminidase 3D structures]]		*[[Beta-N-acetylhexosaminidase 3D structures\|Beta-N-acetylhexosaminidase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:39, 26 July 2023

OCA — Wed, 26 Jul 2023 13:39:40 GMT

←Older revision		Revision as of 13:39, 26 July 2023
Line 3:		Line 3:
	<StructureSection load='5g5k' size='340' side='right'caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='5g5k' size='340' side='right'caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5G5K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G5K FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NOK:2-ACETAMIDO~~-1~~,2-DIDEOXYNOJIRMYCIN'>NOK</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>[http~~:~~//en.wikipedia.org/wiki/Beta~~-N-~~acetylhexosaminidase Beta-N-acetylhexosaminidase]~~, ~~with EC number [http://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NOK:2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN'>NOK</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5g5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g5k OCA], [~~http~~://pdbe.org/5g5k PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5g5k RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5g5k PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5g5k ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g5k OCA], [https://pdbe.org/5g5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g5k RCSB], [https://www.ebi.ac.uk/pdbsum/5g5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g5k ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/NAGZ_PSEAE NAGZ_PSEAE]] Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.[HAMAP-Rule:MF_00364]	+	[https://www.uniprot.org/uniprot/NAGZ_PSEAE NAGZ_PSEAE] Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.[HAMAP-Rule:MF_00364]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]		*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
	*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]		*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]
		+	*[[Beta-N-acetylhexosaminidase 3D structures\|Beta-N-acetylhexosaminidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Acebron, I]]	+	[[Category: Acebron I]]
-	[[Category: Artola-Recolons, C]]	+	[[Category: Artola-Recolons C]]
-	[[Category: Hermoso~~, J A~~]]	+	[[Category: Hermoso JA]]
-	[[Category: Mahasenan, K]]	+	[[Category: Mahasenan K]]
-	[[Category: Mobashery, S]]	+	[[Category: Mobashery S]]
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Beta-hexosaminidase]]~~	+
-	~~[[Category: Cell-wall recycling]]~~	+
-	~~[[Category: Glycoside hydrolase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Inhibition]]~~	+
-	~~[[Category: N-acetylglucosaminidase]]~~	+
-	~~[[Category: Peptidoglycan~~]]	+

OCA at 06:40, 13 May 2020

OCA — Wed, 13 May 2020 06:40:02 GMT

←Older revision		Revision as of 06:40, 13 May 2020
Line 1:		Line 1:

	==Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin==		==Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin==
-	<StructureSection load='5g5k' size='340' side='right' caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='5g5k' size='340' side='right'caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5G5K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5G5K FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOK:2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN'>NOK</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NOK:2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN'>NOK</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5g5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g5k OCA], [http://pdbe.org/5g5k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g5k RCSB], [http://www.ebi.ac.uk/pdbsum/5g5k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g5k ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5g5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g5k OCA], [http://pdbe.org/5g5k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g5k RCSB], [http://www.ebi.ac.uk/pdbsum/5g5k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g5k ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5g5k" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5g5k" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
		+	*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
		+	[[Category: Large Structures]]
	[[Category: Pseae]]		[[Category: Pseae]]
	[[Category: Acebron, I]]		[[Category: Acebron, I]]

OCA at 17:17, 15 November 2017

OCA — Wed, 15 Nov 2017 17:17:26 GMT

←Older revision		Revision as of 17:17, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='5g5k' size='340' side='right' caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='5g5k' size='340' side='right' caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G5K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G5K FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOK:2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN'>NOK</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOK:2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN'>NOK</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
		+	[[Category: Pseae]]
	[[Category: Acebron, I]]		[[Category: Acebron, I]]
	[[Category: Artola-Recolons, C]]		[[Category: Artola-Recolons, C]]

OCA at 15:40, 17 May 2017

OCA — Wed, 17 May 2017 15:40:35 GMT

←Older revision		Revision as of 15:40, 17 May 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5g5k is ~~ON HOLD until Paper~~ Publication	+	==Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin==
		+	<StructureSection load='5g5k' size='340' side='right' caption='[[5g5k]], [[Resolution\|resolution]] 3.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5g5k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G5K FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOK:2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN'>NOK</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g5k OCA], [http://pdbe.org/5g5k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g5k RCSB], [http://www.ebi.ac.uk/pdbsum/5g5k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g5k ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NAGZ_PSEAE NAGZ_PSEAE]] Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.[HAMAP-Rule:MF_00364]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The N-acetylglucosaminidase NagZ of Pseudomonas aeruginosa catalyzes the first cytoplasmic step in recycling of muropeptides, cell-wall-derived natural products. This reaction regulates gene expression for the beta-lactam resistance enzyme, beta-lactamase. The enzyme catalyzes hydrolysis of N-acetyl-beta-d-glucosamine-(1-->4)-1,6-anhydro-N-acetyl-beta-d-muramyl-peptide (1) to N-acetyl-beta-d-glucosamine (2) and 1,6-anhydro-N-acetyl-beta-d-muramyl-peptide (3). The structural and functional aspects of catalysis by NagZ were investigated by a total of seven X-ray structures, three computational models based on the X-ray structures, molecular-dynamics simulations and mutagenesis. The structural insights came from the unbound state and complexes of NagZ with the substrate, products and a mimetic of the transient oxocarbenium species, which were prepared by synthesis. The mechanism involves a histidine as acid/base catalyst, which is unique for glycosidases. The turnover process utilizes covalent modification of D244, requiring two transition-state species and is regulated by coordination with a zinc ion. The analysis provides a seamless continuum for the catalytic cycle, incorporating large motions by four loops that surround the active site.

-	~~Authors: Acebron~~, I., Artola-Recolons, C., ~~Mahasenan~~, ~~K., Mobashery, S.~~, Hermoso, J.A.	+	Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa.,Acebron I, Mahasenan KV, De Benedetti S, Lee M, Artola-Recolons C, Hesek D, Wang H, Hermoso JA, Mobashery S J Am Chem Soc. 2017 May 10. doi: 10.1021/jacs.7b01626. PMID:28482153<ref>PMID:28482153</ref>

-	~~Description: Crystal structure~~ of ~~NagZ from Pseudomonas aeruginosa in complex with~~ the ~~inhibitor 2~~-~~acetamido~~-~~1,2-dideoxynojirimycin~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	~~[[Category: Mobashery, S]]~~	+	<div class="pdbe-citations 5g5k" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Mahasenan, K~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Acebron, I]]		[[Category: Acebron, I]]
-	[[Category: Hermoso, J.A]]
	[[Category: Artola-Recolons, C]]		[[Category: Artola-Recolons, C]]
		+	[[Category: Hermoso, J A]]
		+	[[Category: Mahasenan, K]]
		+	[[Category: Mobashery, S]]
		+	[[Category: Antibiotic resistance]]
		+	[[Category: Beta-hexosaminidase]]
		+	[[Category: Cell-wall recycling]]
		+	[[Category: Glycoside hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibition]]
		+	[[Category: N-acetylglucosaminidase]]
		+	[[Category: Peptidoglycan]]

OCA at 06:34, 10 May 2017

OCA — Wed, 10 May 2017 06:34:06 GMT

←Older revision		Revision as of 06:34, 10 May 2017
Line 9:		Line 9:
	[[Category: Mobashery, S]]		[[Category: Mobashery, S]]
	[[Category: Mahasenan, K]]		[[Category: Mahasenan, K]]
-	[[Category: Hermoso, J.A]]
	[[Category: Acebron, I]]		[[Category: Acebron, I]]
		+	[[Category: Hermoso, J.A]]
	[[Category: Artola-Recolons, C]]		[[Category: Artola-Recolons, C]]

OCA at 08:52, 9 March 2017

OCA — Thu, 09 Mar 2017 08:52:14 GMT

←Older revision		Revision as of 08:52, 9 March 2017
Line 7:		Line 7:
	Description: Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin		Description: Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Acebron, I]]
	[[Category: Mobashery, S]]		[[Category: Mobashery, S]]
	[[Category: Mahasenan, K]]		[[Category: Mahasenan, K]]
	[[Category: Hermoso, J.A]]		[[Category: Hermoso, J.A]]
		+	[[Category: Acebron, I]]
	[[Category: Artola-Recolons, C]]		[[Category: Artola-Recolons, C]]

OCA at 11:06, 20 June 2016

OCA — Mon, 20 Jun 2016 11:06:42 GMT

←Older revision		Revision as of 11:06, 20 June 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5g5k is ON HOLD	+	The entry 5g5k is ON HOLD until Paper Publication

	Authors: Acebron, I., Artola-Recolons, C., Mahasenan, K., Mobashery, S., Hermoso, J.A.		Authors: Acebron, I., Artola-Recolons, C., Mahasenan, K., Mobashery, S., Hermoso, J.A.

OCA: Protected "5g5k" [edit=sysop:move=sysop]

OCA — Wed, 01 Jun 2016 11:43:33 GMT

Protected "5g5k" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:43, 1 June 2016

OCA: New page: '''Unreleased structure''' The entry 5g5k is ON HOLD Authors: Acebron, I., Artola-Recolons, C., Mahasenan, K., Mobashery, S., Hermoso, J.A. Description: Crystal structure of NagZ from ...

OCA — Wed, 01 Jun 2016 11:43:32 GMT

New page: '''Unreleased structure''' The entry 5g5k is ON HOLD Authors: Acebron, I., Artola-Recolons, C., Mahasenan, K., Mobashery, S., Hermoso, J.A. Description: Crystal structure of NagZ from ...

New page

'''Unreleased structure'''

The entry 5g5k is ON HOLD

Authors: Acebron, I., Artola-Recolons, C., Mahasenan, K., Mobashery, S., Hermoso, J.A.

Description: Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin
[[Category: Unreleased Structures]]
[[Category: Acebron, I]]
[[Category: Mobashery, S]]
[[Category: Mahasenan, K]]
[[Category: Hermoso, J.A]]
[[Category: Artola-Recolons, C]]