5ght - Revision history

OCA at 11:31, 2 August 2023

OCA — Wed, 02 Aug 2023 11:31:56 GMT

←Older revision		Revision as of 11:31, 2 August 2023
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	==DNA replication protein==		==DNA replication protein==
-	<StructureSection load='5ght' size='340' side='right' caption='[[5ght]], [[Resolution\|resolution]] 2.79Å' scene=''>	+	<StructureSection load='5ght' size='340' side='right'caption='[[5ght]], [[Resolution\|resolution]] 2.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ght]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pyrococcus_kodakaraensis_(strain_kod1) Pyrococcus kodakaraensis (strain kod1)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GHT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5GHT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ght]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GHT FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5ghr\|5ghr]], [[5ghs\|5ghs]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.795Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">TK1252 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=69014 Pyrococcus kodakaraensis (strain KOD1)])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ght OCA], [https://pdbe.org/5ght PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ght RCSB], [https://www.ebi.ac.uk/pdbsum/5ght PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ght ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ght OCA], [~~http~~://pdbe.org/5ght PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ght RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ght PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ght ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5JGL0_THEKO Q5JGL0_THEKO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 5ght" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5ght" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Exonuclease 3D structures\|Exonuclease 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Oyama, T~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Dna binding protein~~]]	+	[[Category: Thermococcus kodakarensis KOD1]]
-	[[Category: ~~Dna replication~~]]	+	[[Category: Oyama T]]

OCA at 07:32, 6 December 2017

OCA — Wed, 06 Dec 2017 07:32:08 GMT

←Older revision		Revision as of 07:32, 6 December 2017
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	<StructureSection load='5ght' size='340' side='right' caption='[[5ght]], [[Resolution\|resolution]] 2.79Å' scene=''>		<StructureSection load='5ght' size='340' side='right' caption='[[5ght]], [[Resolution\|resolution]] 2.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ght]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GHT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ght]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_kodakaraensis_(strain_kod1) Pyrococcus kodakaraensis (strain kod1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GHT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ghr\|5ghr]], [[5ghs\|5ghs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ghr\|5ghr]], [[5ghs\|5ghs]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TK1252 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69014 Pyrococcus kodakaraensis (strain KOD1)])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ght OCA], [http://pdbe.org/5ght PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ght RCSB], [http://www.ebi.ac.uk/pdbsum/5ght PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ght ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ght OCA], [http://pdbe.org/5ght PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ght RCSB], [http://www.ebi.ac.uk/pdbsum/5ght PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ght ProSAT]</span></td></tr>
	</table>		</table>

OCA at 17:38, 19 October 2016

OCA — Wed, 19 Oct 2016 17:38:50 GMT

←Older revision		Revision as of 17:38, 19 October 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 5ght is ~~ON HOLD until Paper~~ Publication	+	==DNA replication protein==
		+	<StructureSection load='5ght' size='340' side='right' caption='[[5ght]], [[Resolution\|resolution]] 2.79Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5ght]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GHT FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ghr\|5ghr]], [[5ghs\|5ghs]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ght OCA], [http://pdbe.org/5ght PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ght RCSB], [http://www.ebi.ac.uk/pdbsum/5ght PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ght ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In eukaryotic DNA replication initiation, hexameric MCM (mini-chromosome maintenance) unwinds the template double-stranded DNA to form the replication fork. MCM is activated by two proteins, Cdc45 and GINS, which constitute the 'CMG' unwindosome complex together with the MCM core. The archaeal DNA replication system is quite similar to that of eukaryotes, but only limited knowledge about the DNA unwinding mechanism is available, from a structural point of view. Here, we describe the crystal structure of an archaeal GAN (GINS-associated nuclease) from Thermococcus kodakaraensis, the homolog of eukaryotic Cdc45, in both the free form and the complex with the C-terminal domain of the cognate Gins51 subunit (Gins51C). This first archaeal GAN structure exhibits a unique, 'hybrid' structure between the bacterial RecJ and the eukaryotic Cdc45. GAN possesses the conserved DHH and DHH1 domains responsible for the exonuclease activity, and an inserted CID (CMG interacting domain)-like domain structurally comparable to that in Cdc45, suggesting its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. A structural comparison of the GAN-Gins51C complex with the GINS tetramer suggests that GINS uses the mobile Gins51C as a hook to bind GAN for CMG formation.

-	~~Authors:~~ Oyama, T.	+	Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication.,Oyama T, Ishino S, Shirai T, Yamagami T, Nagata M, Ogino H, Kusunoki M, Ishino Y Nucleic Acids Res. 2016 Sep 5. pii: gkw789. PMID:27599844<ref>PMID:27599844</ref>

-	~~Description: DNA replication protein~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5ght" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Oyama, T]]		[[Category: Oyama, T]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Dna replication]]

OCA at 08:16, 21 September 2016

OCA — Wed, 21 Sep 2016 08:16:07 GMT

←Older revision		Revision as of 08:16, 21 September 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5ght is ON HOLD	+	The entry 5ght is ON HOLD until Paper Publication

	Authors: Oyama, T.		Authors: Oyama, T.

OCA: Protected "5ght" [edit=sysop:move=sysop]

OCA — Tue, 12 Jul 2016 21:34:30 GMT

Protected "5ght" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:34, 12 July 2016

OCA: New page: '''Unreleased structure''' The entry 5ght is ON HOLD Authors: Oyama, T. Description: DNA replication protein Category: Unreleased Structures Category: Oyama, T

OCA — Tue, 12 Jul 2016 21:34:28 GMT

New page: '''Unreleased structure''' The entry 5ght is ON HOLD Authors: Oyama, T. Description: DNA replication protein Category: Unreleased Structures Category: Oyama, T

New page

'''Unreleased structure'''

The entry 5ght is ON HOLD

Authors: Oyama, T.

Description: DNA replication protein
[[Category: Unreleased Structures]]
[[Category: Oyama, T]]