5giz - Revision history

OCA at 11:32, 2 August 2023

OCA — Wed, 02 Aug 2023 11:32:47 GMT

←Older revision		Revision as of 11:32, 2 August 2023
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	==Periplasmic heme-binding protein BhuT in apo form==		==Periplasmic heme-binding protein BhuT in apo form==
-	<StructureSection load='5giz' size='340' side='right' caption='[[5giz]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='5giz' size='340' side='right'caption='[[5giz]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5giz]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Burcj Burcj~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5GIZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5giz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GIZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=CL:CHLORIDE+ION'>CL</scene~~>, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[5gj0\|5gj0]], [[5gj1\|5gj1]], [[5gj2\|5gj2]], [[5gj3\|5gj3]]~~<~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">hmuT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5giz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giz OCA], [https://pdbe.org/5giz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5giz RCSB], [https://www.ebi.ac.uk/pdbsum/5giz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5giz ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5giz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giz OCA], [~~http~~://pdbe.org/5giz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5giz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5giz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5giz ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B4EKB3_BURCJ B4EKB3_BURCJ]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Burcj~~]]	+	[[Category: Burkholderia cenocepacia J2315]]
-	[[Category: Nakamura, N]]	+	[[Category: Large Structures]]
-	[[Category: Naoe, Y]]	+	[[Category: Nakamura N]]
-	[[Category: Rahman~~, M M~~]]	+	[[Category: Naoe Y]]
-	[[Category: Shiro, Y]]	+	[[Category: Rahman MM]]
-	[[Category: Sugimoto, H]]	+	[[Category: Shiro Y]]
-	~~[[Category: Metal transport]]~~	+	[[Category: Sugimoto H]]
-	~~[[Category: Transport protein~~]]	+

OCA at 10:07, 15 November 2017

OCA — Wed, 15 Nov 2017 10:07:57 GMT

←Older revision		Revision as of 10:07, 15 November 2017
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	<StructureSection load='5giz' size='340' side='right' caption='[[5giz]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='5giz' size='340' side='right' caption='[[5giz]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5giz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GIZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5giz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burcj Burcj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GIZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5gj0\|5gj0]], [[5gj1\|5gj1]], [[5gj2\|5gj2]], [[5gj3\|5gj3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5gj0\|5gj0]], [[5gj1\|5gj1]], [[5gj2\|5gj2]], [[5gj3\|5gj3]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hmuT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5giz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giz OCA], [http://pdbe.org/5giz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5giz RCSB], [http://www.ebi.ac.uk/pdbsum/5giz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5giz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5giz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giz OCA], [http://pdbe.org/5giz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5giz RCSB], [http://www.ebi.ac.uk/pdbsum/5giz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5giz ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Burcj]]
	[[Category: Nakamura, N]]		[[Category: Nakamura, N]]
	[[Category: Naoe, Y]]		[[Category: Naoe, Y]]

OCA at 06:50, 11 October 2017

OCA — Wed, 11 Oct 2017 06:50:32 GMT

←Older revision		Revision as of 06:50, 11 October 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5giz is ~~ON HOLD until Paper~~ Publication	+	==Periplasmic heme-binding protein BhuT in apo form==
		+	<StructureSection load='5giz' size='340' side='right' caption='[[5giz]], [[Resolution\|resolution]] 1.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5giz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GIZ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5gj0\|5gj0]], [[5gj1\|5gj1]], [[5gj2\|5gj2]], [[5gj3\|5gj3]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5giz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giz OCA], [http://pdbe.org/5giz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5giz RCSB], [http://www.ebi.ac.uk/pdbsum/5giz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5giz ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Periplasmic heme-binding proteins (PBPs) in Gram-negative bacteria are components of the heme acquisition system. These proteins shuttle heme across the periplasmic space from outer membrane receptors to ATP-binding cassette (ABC) heme importers located in the inner-membrane. In the present study, we characterized the structures of PBPs found in the pathogen Burkholderia cenocepacia (BhuT) and in the thermophile Roseiflexus sp. RS-1 (RhuT) in the heme-free and heme-bound forms. The conserved motif, in which a well-conserved Tyr interacts with the nearby Arg coordinates on heme iron, was observed in both PBPs. The heme was recognized by its surroundings in a variety of manners including hydrophobic interactions and hydrogen bonds, which was confirmed by isothermal titration calorimetry. Furthermore, this study of 3 forms of BhuT allowed the first structural comparison and showed that the heme-binding cleft of BhuT adopts an "open" state in the heme-free and 2-heme-bound forms, and a "closed" state in the one-heme-bound form with unique conformational changes. Such a conformational change might adjust the interaction of the heme(s) with the residues in PBP and facilitate the transfer of the heme into the translocation channel of the importer.

-	~~Authors~~:	+	Structural basis for binding and transfer of heme in bacterial heme-acquisition systems.,Naoe Y, Nakamura N, Rahman MM, Tosha T, Nagatoishi S, Tsumoto K, Shiro Y, Sugimoto H Proteins. 2017 Sep 14. doi: 10.1002/prot.25386. PMID:28913898<ref>PMID:28913898</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5giz" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Nakamura, N]]
		+	[[Category: Naoe, Y]]
		+	[[Category: Rahman, M M]]
		+	[[Category: Shiro, Y]]
		+	[[Category: Sugimoto, H]]
		+	[[Category: Metal transport]]
		+	[[Category: Transport protein]]

OCA: Protected "5giz" [edit=sysop:move=sysop]

OCA — Tue, 12 Jul 2016 21:37:46 GMT

Protected "5giz" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:37, 12 July 2016

OCA: New page: '''Unreleased structure''' The entry 5giz is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

OCA — Tue, 12 Jul 2016 21:37:44 GMT

New page: '''Unreleased structure''' The entry 5giz is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5giz is ON HOLD until Paper Publication

Authors:

Description:
[[Category: Unreleased Structures]]