5gu5 - Revision history

OCA at 11:42, 2 August 2023

OCA — Wed, 02 Aug 2023 11:42:34 GMT

←Older revision		Revision as of 11:42, 2 August 2023
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	<StructureSection load='5gu5' size='340' side='right'caption='[[5gu5]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='5gu5' size='340' side='right'caption='[[5gu5]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5gu5]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5GU5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5gu5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GU5 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=BR:BROMIDE+ION'>BR</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~Tmed5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=10090 LK3 transgenic mice])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5gu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu5 OCA], [~~http~~://pdbe.org/5gu5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5gu5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5gu5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu5 OCA], [https://pdbe.org/5gu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gu5 RCSB], [https://www.ebi.ac.uk/pdbsum/5gu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/TMED5_MOUSE TMED5_MOUSE]] Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport (By similarity).	+	[https://www.uniprot.org/uniprot/TMED5_MOUSE TMED5_MOUSE] Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Nagae, M]]	+	[[Category: Nagae M]]
-	[[Category: Yamaguchi, Y]]	+	[[Category: Yamaguchi Y]]
-	~~[[Category: Gpi-anchored protein]]~~	+
-	~~[[Category: P24 protein family]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 10:10, 26 February 2020

OCA — Wed, 26 Feb 2020 10:10:19 GMT

←Older revision		Revision as of 10:10, 26 February 2020
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	==Crystal structure of p24gamma2 GOLD domain determined by sulfur-SAD==		==Crystal structure of p24gamma2 GOLD domain determined by sulfur-SAD==
-	<StructureSection load='5gu5' size='340' side='right' caption='[[5gu5]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='5gu5' size='340' side='right'caption='[[5gu5]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5gu5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GU5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5gu5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GU5 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tmed5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu5 OCA], [http://pdbe.org/5gu5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gu5 RCSB], [http://www.ebi.ac.uk/pdbsum/5gu5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu5 OCA], [http://pdbe.org/5gu5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gu5 RCSB], [http://www.ebi.ac.uk/pdbsum/5gu5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu5 ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Lk3 transgenic mice]]
	[[Category: Nagae, M]]		[[Category: Nagae, M]]
	[[Category: Yamaguchi, Y]]		[[Category: Yamaguchi, Y]]

OCA at 23:32, 25 January 2017

OCA — Wed, 25 Jan 2017 23:32:03 GMT

←Older revision		Revision as of 23:32, 25 January 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5gu5 is ~~ON HOLD~~	+	==Crystal structure of p24gamma2 GOLD domain determined by sulfur-SAD==
		+	<StructureSection load='5gu5' size='340' side='right' caption='[[5gu5]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5gu5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GU5 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gu5 OCA], [http://pdbe.org/5gu5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gu5 RCSB], [http://www.ebi.ac.uk/pdbsum/5gu5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gu5 ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TMED5_MOUSE TMED5_MOUSE]] Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The p24 family proteins form homo- and hetero-oligomeric complexes for efficient transport of cargo proteins from the endoplasmic reticulum to the Golgi apparatus. It consists of four subfamilies (p24alpha, p24beta, p24gamma, and p24delta). p24gamma2 plays crucial roles in the selective transport of glycosylphosphatidylinositol-anchored proteins. Here, we determined the crystal structure of mouse p24gamma2 Golgi dynamics (GOLD) domain at 2.8 A resolution by the single anomalous diffraction method using intrinsic sulfur atoms. In spite of low sequence identity among p24 family proteins, p24gamma2 GOLD domain assumes a beta-sandwich fold, similar to that of p24beta1 or p24delta1. An additional short alpha-helix is observed at the C-terminus of the p24gamma2 GOLD domain. Intriguingly, p24gamma2 GOLD domains crystallize as dimers, and dimer formation seems assisted by the short alpha-helix. Dimerization modes of GOLD domains are compared among p24 family proteins. Proteins 2017. (c) 2017 Wiley Periodicals, Inc.

-	~~Authors~~:	+	Crystallographic analysis of murine p24gamma2 Golgi dynamics domain.,Nagae M, Liebschner D, Yamada Y, Morita-Matsumoto K, Matsugaki N, Senda T, Fujita M, Kinoshita T, Yamaguchi Y Proteins. 2017 Jan 9. doi: 10.1002/prot.25242. PMID:28066915<ref>PMID:28066915</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5gu5" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Nagae, M]]
		+	[[Category: Yamaguchi, Y]]
		+	[[Category: Gpi-anchored protein]]
		+	[[Category: P24 protein family]]
		+	[[Category: Transport protein]]

OCA: Protected "5gu5" [edit=sysop:move=sysop]

OCA — Fri, 09 Sep 2016 12:04:55 GMT

Protected "5gu5" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:04, 9 September 2016

OCA: New page: '''Unreleased structure''' The entry 5gu5 is ON HOLD Authors: Description: Category: Unreleased Structures

OCA — Fri, 09 Sep 2016 12:04:54 GMT

New page: '''Unreleased structure''' The entry 5gu5 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 5gu5 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]