5gwe - Revision history

OCA at 11:44, 2 August 2023

OCA — Wed, 02 Aug 2023 11:44:37 GMT

←Older revision		Revision as of 11:44, 2 August 2023
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	<StructureSection load='5gwe' size='340' side='right'caption='[[5gwe]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='5gwe' size='340' side='right'caption='[[5gwe]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5gwe]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5GWE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5gwe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GWE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GWM:(4-methylphenyl)+dihydrogen+phosphate'>GWM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwe OCA], [~~http~~://pdbe.org/5gwe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5gwe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5gwe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwe ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GWM:(4-methylphenyl)+dihydrogen+phosphate'>GWM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwe OCA], [https://pdbe.org/5gwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gwe RCSB], [https://www.ebi.ac.uk/pdbsum/5gwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwe ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8NSW2_CORGL Q8NSW2_CORGL]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Corynebacterium glutamicum ATCC 13032]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dong, S]]	+	[[Category: Dong S]]
-	[[Category: Feng, Y]]	+	[[Category: Feng Y]]
-	[[Category: Wang, X]]	+	[[Category: Wang X]]
-	[[Category: Liu, X]]	+	[[Category: Liu X]]
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Cytochrome p450]]~~	+
-	~~[[Category: Electron transport~~]]	+

OCA at 06:45, 20 May 2020

OCA — Wed, 20 May 2020 06:45:03 GMT

←Older revision		Revision as of 06:45, 20 May 2020
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	==cytochrome P450 CREJ==		==cytochrome P450 CREJ==
-	<StructureSection load='5gwe' size='340' side='right' caption='[[5gwe]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='5gwe' size='340' side='right'caption='[[5gwe]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5gwe]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5GWE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5gwe]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GWE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GWM:(4-methylphenyl)+dihydrogen+phosphate'>GWM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GWM:(4-methylphenyl)+dihydrogen+phosphate'>GWM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwe OCA], [http://pdbe.org/5gwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gwe RCSB], [http://www.ebi.ac.uk/pdbsum/5gwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwe ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwe OCA], [http://pdbe.org/5gwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gwe RCSB], [http://www.ebi.ac.uk/pdbsum/5gwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwe ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 5gwe" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5gwe" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Dong, S]]		[[Category: Dong, S]]
	[[Category: Feng, Y]]		[[Category: Feng, Y]]

OCA at 10:24, 10 September 2017

OCA — Sun, 10 Sep 2017 10:24:20 GMT

←Older revision		Revision as of 10:24, 10 September 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5gwe is ~~ON HOLD until Sep 11 2018~~	+	==cytochrome P450 CREJ==
		+	<StructureSection load='5gwe' size='340' side='right' caption='[[5gwe]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5gwe]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GWE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GWM:(4-methylphenyl)+dihydrogen+phosphate'>GWM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gwe OCA], [http://pdbe.org/5gwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gwe RCSB], [http://www.ebi.ac.uk/pdbsum/5gwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gwe ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Selective oxidation of aliphatic C-H bonds in alkylphenols serves significant roles not only in generation of functionalized intermediates that can be used to synthesize diverse downstream chemical products, but also in biological degradation of these environmentally hazardous compounds. Chemo-, regio-, and stereoselectivity; controllability; and environmental impact represent the major challenges for chemical oxidation of alkylphenols. Here, we report the development of a unique chemomimetic biocatalytic system originated from the Gram-positive bacterium Corynebacterium glutamicum The system consisting of CreHI (for installation of a phosphate directing/anchoring group), CreJEF/CreG/CreC (for oxidation of alkylphenols), and CreD (for directing/anchoring group offloading) is able to selectively oxidize the aliphatic C-H bonds of p- and m-alkylated phenols in a controllable manner. Moreover, the crystal structures of the central P450 biocatalyst CreJ in complex with two representative substrates provide significant structural insights into its substrate flexibility and reaction selectivity.

-	~~Authors: Dong, S~~., ~~liu~~, X., Wang, X., ~~Feng~~, Y.	+	Selective oxidation of aliphatic C-H bonds in alkylphenols by a chemomimetic biocatalytic system.,Du L, Dong S, Zhang X, Jiang C, Chen J, Yao L, Wang X, Wan X, Liu X, Wang X, Huang S, Cui Q, Feng Y, Liu SJ, Li S Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5129-E5137. doi:, 10.1073/pnas.1702317114. Epub 2017 Jun 12. PMID:28607077<ref>PMID:28607077</ref>

-	~~Description: cytochrome P450 CREJ~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5gwe" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Dong, S]]		[[Category: Dong, S]]
-	[[Category: Liu, X]]
-	[[Category: Wang, X]]
	[[Category: Feng, Y]]		[[Category: Feng, Y]]
		+	[[Category: Wang, X]]
		+	[[Category: Liu, X]]
		+	[[Category: Complex]]
		+	[[Category: Cytochrome p450]]
		+	[[Category: Electron transport]]

OCA at 16:14, 5 October 2016

OCA — Wed, 05 Oct 2016 16:14:43 GMT

←Older revision		Revision as of 16:14, 5 October 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5gwe is ON HOLD	+	The entry 5gwe is ON HOLD until Sep 11 2018

	Authors: Dong, S., liu, X., Wang, X., Feng, Y.		Authors: Dong, S., liu, X., Wang, X., Feng, Y.

OCA at 11:30, 3 October 2016

OCA — Mon, 03 Oct 2016 11:30:07 GMT

←Older revision		Revision as of 11:30, 3 October 2016
Line 3:		Line 3:
	The entry 5gwe is ON HOLD		The entry 5gwe is ON HOLD

-	Authors: ~~Sheng~~ Dong, Xi liu, ~~Xinquan~~ Wang, ~~Yingang~~ Feng	+	Authors: Dong, S., liu, X., Wang, X., Feng, Y.

	Description: cytochrome P450 CREJ		Description: cytochrome P450 CREJ
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Sheng~~ Dong, Xi Liu, ~~Xinquan~~ Wang, ~~Yingang~~ Feng]]	+	[[Category: Dong, S]]
		+	[[Category: Liu, X]]
		+	[[Category: Wang, X]]
		+	[[Category: Feng, Y]]

OCA: Protected "5gwe" [edit=sysop:move=sysop]

OCA — Wed, 21 Sep 2016 08:42:55 GMT

Protected "5gwe" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:42, 21 September 2016

OCA: New page: '''Unreleased structure''' The entry 5gwe is ON HOLD Authors: Sheng Dong, Xi liu, Xinquan Wang, Yingang Feng Description: cytochrome P450 CREJ Category: Unreleased Structures [[Cat...

OCA — Wed, 21 Sep 2016 08:42:53 GMT

New page: '''Unreleased structure''' The entry 5gwe is ON HOLD Authors: Sheng Dong, Xi liu, Xinquan Wang, Yingang Feng Description: cytochrome P450 CREJ Category: Unreleased Structures [[Cat...

New page

'''Unreleased structure'''

The entry 5gwe is ON HOLD

Authors: Sheng Dong, Xi liu, Xinquan Wang, Yingang Feng

Description: cytochrome P450 CREJ
[[Category: Unreleased Structures]]
[[Category: Sheng Dong, Xi Liu, Xinquan Wang, Yingang Feng]]